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ClinicalTrials.gov public records Last synced Sep 6, 2026, 5:33 AM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Terminated Phase 4 Interventional Results available

Calcium Sulfate Spacer in Open Tibia Fractures

NCT03042546
View directory record Official record
Conditions
Open tíbia Fracture With Sub-segmental Bone Loss
Interventions
Calcium Sulfate, PMMA, No treatment
Drug · Other
Lead sponsor
University of Washington
Other
Eligibility
16 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 6, 2026, 5:33 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

NCT03295981
View directory record Official record
Conditions
Giant Cell Tumor of Bone
Interventions
Zoledronic Acid
Drug
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
14
States / cities
Los Angeles, California • Indianapolis, Indiana • Iowa City, Iowa + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Open-Label Study to Evaluate the Immunogenicity of Bovine Collagen in ArteFill® by Skin Testing

NCT00778089
View directory record Official record
Conditions
Hypersensitivity
Interventions
ArteFill® Skin Test
Device
Lead sponsor
Suneva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs

NCT01871519
View directory record Official record
Conditions
Compression Fracture of Vertebral Body, Osteoporosis, Cancer
Interventions
Balloon kyphoplasty
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
65 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Fremont, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Not applicable Interventional Results available

Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects

NCT02015390
View directory record Official record
Conditions
Segmental Long Bone Defects
Interventions
Autogenous RIA bone grafting, Allogeneic bone grafting
Procedure
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2021 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Antibiotic Loaded Cement After TKA

NCT05429671
View directory record Official record
Conditions
Total Knee Arthoplasty
Interventions
total knee arthroplasty, Tobramycin, Gentamicin, Antibiotic cement spacer
Procedure · Drug · Device
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Phase 1 Interventional

Pilot Immunotherapy Trial for Recurrent Malignant Gliomas

NCT01550523
View directory record Official record
Conditions
Malignant Glioma of Brain
Interventions
IGF-1R/AS ODN, biodiffusion chamber
Drug · Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Phase 2 Interventional

Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients

NCT00001311
View directory record Official record
Conditions
Cataracts
Interventions
heparin-surface modified intraocular lens
Device
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 6, 2026, 5:33 AM EDT
Withdrawn Not applicable Interventional

Phototherapy For Treatment Of Raynaud's Phenomenon

NCT04898036
View directory record Official record
Conditions
Raynaud Disease, Raynaud Phenomenon, Raynaud Syndrome
Interventions
Blue Light Therapy, Sham Light Therapy
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Sep 6, 2026, 5:33 AM EDT
Recruiting Not applicable Interventional

Transcranial Ultrasound Via Sonolucent Cranioplasty

NCT06097845
View directory record Official record
Conditions
Cranioplasty, Sonolucent Cranioplasty, Reconstructive Cranioplasty
Interventions
Transcranial Ultrasound
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 6, 2026, 5:33 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

OsseoFix™ Spinal Fracture Reduction System in Treating Spinal Compression Fracture

NCT00961714
View directory record Official record
Conditions
Vertebral Compression Fractures
Interventions
OsseoFix Spinal Fracture Reduction System
Device
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
50 Years to 105 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
11
States / cities
La Jolla, California • Boulder, Colorado • Littleton, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 6, 2026, 5:33 AM EDT
Not yet recruiting Not applicable Interventional

Clinical Outcomes of 3D Printed and Milled Complete Dentures

NCT07586774
View directory record Official record
Conditions
Edentulous Mouth, Edentulous Jaw
Interventions
Lucitone Digital Print, Lucitone Digital Fit
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Phase 4 Interventional

FREE Study - Fracture Reduction Evaluation

NCT00211211
View directory record Official record
Conditions
Osteopenia, Osteoporosis, Multiple Myeloma, Bone Neoplasms
Interventions
Balloon Kyphoplasty
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 6, 2026, 5:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

COVID-19 Testing Sample Acquisition Throughput and Efficiency

NCT04532411
View directory record Official record
Conditions
SARS-CoV Infection, Respiratory Viral Infection, Personal Protective Equipment, Covid19
Interventions
Personal Protective Testing Booth
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
28,948 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Phase 4 Interventional Results available

Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures

NCT01383616
View directory record Official record
Conditions
Vertebral Compression Fracture
Interventions
Kyphon® Balloon Kyphoplasty (Kyphon Inc; Sunnydale, CA)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 100 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 6, 2026, 5:33 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Feasibility Study for Fibroblast Autologous Skin Grafts

NCT01964859
View directory record Official record
Conditions
Wounds and Injuries
Interventions
autologous skin fibroblasts, Filler Product
Biological
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Recruiting Not applicable Interventional

Transcranial Ultrasound Via Sonolucent Cranioplasty After Minimally Invasive Intracerebral Hemorrhage Evacuation

NCT05538286
View directory record Official record
Conditions
Transcranial Ultrasound With Sonolucent Cranioplasty, TUSC
Interventions
ClearFit implant, transcranial ultrasonography through sonolucent cranioplasty
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Safety and Efficacy Study for Treatment of Painful Vertebral Compression Fractures Caused by Osteoporosis

NCT00290862
View directory record Official record
Conditions
Spinal Fractures
Interventions
Percutaneous Vertebral Augmentation of compression fractures
Device
Lead sponsor
Orthovita d/b/a Stryker
Industry
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
18
States / cities
Scottsdale, Arizona • Encinitas, California • Rancho Mirage, California + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2008 · Synced Sep 6, 2026, 5:33 AM EDT
Not yet recruiting Not applicable Interventional

Local Antibiotic Concentrations With Tissue Expanders in Breast Reconstruction

NCT07339215
View directory record Official record
Conditions
Tissue Expander Based Breast Reconstruction
Interventions
Antibiotic loaded calcium sulfate beads, Polymethylmethacrylate antibiotic disc
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Recruiting Phase 3 Interventional

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

NCT05615844
View directory record Official record
Conditions
Open tíbia Fracture
Interventions
Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy
Drug · Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
29
States / cities
Chandler, Arizona • Tucson, Arizona • Davis, California + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Phase 3 Interventional Results available

Use of Artefill® for Moderate to Severe Atrophic Acne Scar Correction

NCT01559922
View directory record Official record
Conditions
Atrophic Acne Scar
Interventions
Normal Saline, Artefill
Drug · Device
Lead sponsor
Suneva Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
10
States / cities
Beverly Hills, California • Los Angeles, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 6, 2026, 5:33 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections

NCT06428448
View directory record Official record
Conditions
Periprosthetic Joint Infection
Interventions
REMEDY Spectrum IM Spacer Nail
Combination Product
Lead sponsor
OsteoRemedies, LLC
Industry
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Lansing, Michigan • Charlotte, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 6, 2026, 5:33 AM EDT
Completed Not applicable Interventional Results available

Phaco Versus Small Incision Cataract Surgery (SICS) Health Economic Study

NCT00762606
View directory record Official record
Conditions
Cataract
Interventions
Phacoemulsification cataract extraction surgery, Small incision cataract surgery
Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 70 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2012 · Synced Sep 6, 2026, 5:33 AM EDT
Not listed Not applicable Interventional

EyeKon Medical Inc. Capsular Tension Ring Study

NCT02332369
View directory record Official record
Conditions
Cataract Extraction
Interventions
Capsular Tension Ring
Device
Lead sponsor
EyeKon Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2023
U.S. locations
3
States / cities
Venice, Florida • Washington, Missouri • Lake Jackson, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2023 · Synced Sep 6, 2026, 5:33 AM EDT