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ClinicalTrials.gov public records Last synced Nov 12, 2026, 8:44 PM EST

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Showing 25–48 of 169 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Peripheral Nerve Blockade Clear all

Conditions: Analgesia in Total Knee Arthroplasty
Interventions: Ropivicaine, Continuous Femoral Nerve Catheter, Continuous Tibial Nerve Catheter; Drug · Device
Lead sponsor: Texas Tech University Health Sciences Center, El Paso; Other
Eligibility: 18 Years to 85 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: El Paso, Texas

Conditions: Anesthesia
Interventions: Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: Female only
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
Interventions: Exparel, Peripheral Nerve Block; Drug
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: SAH (Subarachnoid Hemorrhage), Headache
Interventions: Transnasal sphenopalatine ganglion block; Combination Product
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 100 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Pain, Postoperative
Interventions: Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Total Knee Replacement Surgery, Post-operative Pain
Interventions: Suzetrigine, Placebo; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 85 Years
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain, Postoperative
Interventions: Single injection peripheral nerve block with liposomal bupivacaine (Exparel), Single injection peripheral nerve block with 0.25% bupivacaine and subsequent peripheral nerve catheter with 0.2% bupivacaine infusion via onQ pain pump; Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Postoperative Pain
Interventions: Bupivacaine; Drug
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 6 Years to 18 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Regional Block for Pain Control, Supraclavicular Block, Ultrasound Guided Block, Block Additive
Interventions: Buprenorphine; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 79 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Vertebral Compression Fracture, Facet Joint Pain
Interventions: Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates, Acetaminophen, Physical therapy, Opioids; Procedure · Drug · Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 90 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Davis, California

Conditions: Post Operative Pain
Interventions: Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel), ambIT Infusion Pump; Drug · Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Somerset, New Jersey

Conditions: Neuromuscular Blockade, Muscle Relaxation
Interventions: Train of four test; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 85 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain Control, Ureteral Reimplantation, Pediatrics, Intrathecal Morphine
Interventions: Intrathecal Morphine, Quadratus lumborum block; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Months to 11 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Anesthesia, Conduction
Interventions: Erector Spinae Plane Block, Paravertebral Block; Procedure
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older · Female only
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Continuous Femoral Nerve Blocks in Healthy Volunteers
Interventions: Catheter Anterior to the Femoral Nerve, Catheter Posterior to the Femoral Nerve; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: San Diego, California

Conditions: Foot Surgery, Ankle Surgery
Interventions: Exparel, Bupivicaine; Drug
Lead sponsor: Campbell Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Germantown, Tennessee

Conditions: Wounds and Injuries, Rib Fractures
Interventions: Ketamine, Placebo, Intercostal Nerve Block, Acetaminophen, Ibuprofen, Pantoprazole, Methocarbamol, Opioid; Drug · Procedure
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Rib Fractures
Interventions: Ropivacaine, Non steroidal anti-inflammatory drug and opioids; Drug
Lead sponsor: Zachary Warriner; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Fracture of Shoulder and Upper Arm
Interventions: 1.3% Liposomal Bupivacaine, 0.125% Bupivacaine; Drug
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Dearborn, Michigan

Conditions: Knee Osteoarthritis, Pain, Postoperative, Acupuncture
Interventions: Acupuncture, Peripheral Nerve Stimulator; Other · Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 70 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Arthropathy Shoulder
Interventions: Liposomal Bupivacaine, Bupivacaine Hydrochloride; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Reversal of Neuromuscular Blockade
Interventions: Sugammadex 2 mg/kg, Sugammadex 4 mg/kg, Sugammadex 16 mg/kg, Neostigmine + Glycopyrrolate, Rocuronium, Vecuronium; Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 20
States / cities: Birmingham, Alabama • Tucson, Arizona • Loma Linda, California + 15 more

Conditions: Anesthesia, Pediatrics, Surgery
Interventions: regional nerve block, Antiemetic; Procedure · Drug
Lead sponsor: Indiana University; Other
Eligibility: 1 Year to 18 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: ACL, Anterior Cruciate Ligament Injuries
Interventions: Genicular Nerve Block with bupivacaine and preservative free dexamethasone; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 80 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Continuous Femoral and Tibial Nerve Blocks in TKA Patients

Decreased Neuraxial Morphine After Cesarean Delivery

Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair

Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic

Duration of Analgesic Effect for Ultrasound Guided Supraclavicular Blocks With the Addition of Buprenorphine to Local Anesthetic Solution

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

Post Operative Infusion Pump Pain Study

Clinical Application of "Train of Four" Testing in the Intraoperative Monitoring Setting

ITM vs QL for Pediatric Open Lower Abdominal Procedures

Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy

Effects of Catheter Tip Location Relative to the Femoral Nerve on Sensory and Motor Function

Periarticular Injection Versus Popliteal Block

Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients

INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures

Exparel for Postoperative Pain Management in Shoulder Surgery

Acupuncture for Low-Dose Opioid for TKA Replacement

Liposomal Bupivacaine Interscalene Nerve Block in Shoulder Arthroplasty

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

Comparative Study of Superficial Cervical Plexus Block and Nerve of Arnold Block and Incidence of PONV for Inner Ear Surgery

Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery