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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:53 AM EDT

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Showing 25–48 of 878 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Placebo Surgery Control Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

EXPAREL for Minimally Invasive Supracervical Hysterectomies

NCT03769714
View directory record Official record
Conditions
Pain
Interventions
Saline Solution for Injection, Exparel
Drug
Lead sponsor
Maimonides Medical Center
Other
Eligibility
35 Years to 75 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Results available

A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery

NCT03827655
View directory record Official record
Conditions
Postoperative Gastrointestinal Dysfunction
Interventions
TAK-954 Placebo, TAK-954
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
19
States / cities
Mobile, Alabama • Los Angeles, California • Orange, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2023 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 4 Interventional Results available

Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery

NCT02512861
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine, Placebo
Drug
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
Up to 17 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient

NCT03671837
View directory record Official record
Conditions
Apneic; Oxygenation
Interventions
Oxygen, Air
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Preoperative Carbohydrate Rich Drinks on Immediate Postoperative Outcome in Total Knee Arthroplasty

NCT03380754
View directory record Official record
Conditions
Post Operative Nausea and Vomiting
Interventions
Nutricia preOp, Nestle Splash Lemon Flavor Water (Placebo)
Dietary Supplement · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Not listed Phase 1Phase 2 Interventional

Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

NCT04205656
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Biological · Other
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
16 Years to 50 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Phase 3 Interventional

QPI-1002 Phase 3 for Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for AKI Following Cardiac Surgery

NCT03510897
View directory record Official record
Conditions
Cardiac Surgery
Interventions
teprasiran, Placebo
Drug
Lead sponsor
Quark Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
1,043 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
36
States / cities
Birmingham, Alabama • Los Angeles, California • New Haven, Connecticut + 28 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 29, 2026, 4:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gabapentin Premedication for ACL Reconstruction: RCT

NCT03417479
View directory record Official record
Conditions
Anterior Cruciate Ligament (ACL) Reconstruction
Interventions
Gabapentin
Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
12 Years to 18 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Phase 3 Interventional

Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery

NCT00458276
View directory record Official record
Conditions
Heart Diseases, Hypertension, Pulmonary
Interventions
tezosentan, placebo
Drug
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
9
States / cities
Stanford, California • New York, New York • Durham, North Carolina + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Use of Human Dehydrated Umbilical Cord Allograft in Supraspinatus Tendon Repair

NCT03084068
View directory record Official record
Conditions
Shoulder Injury, Shoulder Sprain, Supraspinatus Tear
Interventions
Human dehydrated umbilical cord allograft, Placebo
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wexford, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 29, 2026, 4:53 AM EDT
Withdrawn Phase 2 Interventional

Study to Evaluate Sub-retinal Transplantation of Retinal Pigmented Epithelial Cells in Patients With Dry AMD

NCT02563782
View directory record Official record
Conditions
Age-Related Macular Degeneration
Interventions
Sub-retinal transplantation of MA09-hRPE cells, tacrolimus and mycophenolate mofetil, Placebo tacrolimus and mycophenolate mofetil, Sham Surgery
Biological · Drug · Procedure
Lead sponsor
Astellas Institute for Regenerative Medicine
Industry
Eligibility
50 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 26, 2017 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 4 Interventional Results available

Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery

NCT03287089
View directory record Official record
Conditions
Catheter-Associated Urinary Tract Infection
Interventions
Nitrofurantoin 100 MG, Placebo Oral Tablet
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty

NCT01037985
View directory record Official record
Conditions
Scar Prevention
Interventions
EXC 001, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 45 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
6
States / cities
La Jolla, California • Chicago, Illinois • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Phase 3 Interventional

Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery

NCT06843538
View directory record Official record
Conditions
Postoperative Urinary Retention (POUR)
Interventions
Tamsulosin, Placebo
Drug
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 4 Interventional Results available

Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?

NCT01714336
View directory record Official record
Conditions
Hip Fracture
Interventions
tranexamic acid, placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Acetaminophen for Post Surgical Dental Pain

NCT04018612
View directory record Official record
Conditions
Pain, Postoperative, Dental Pain
Interventions
Acetaminophen, Placebo
Drug · Other
Lead sponsor
Nevakar, Inc.
Industry
Eligibility
17 Years to 55 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Phase 4 Interventional Results available

Serratus Plane Block for Postoperative Pain Control

NCT02865928
View directory record Official record
Conditions
Outpatient Breast Surgery, Mastopexy, Augmentation, Revision
Interventions
Bupivicaine HCl, Normal Saline
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Gabapentin for Perioperative Pain Relief in Surgical Abortion

NCT04292171
View directory record Official record
Conditions
Pain Control
Interventions
Gabapentin, Placebos
Drug
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older · Female only
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery

NCT04554693
View directory record Official record
Conditions
Endometriosis, Endometriosis-related Pain
Interventions
Metronidazole Oral, Placebo
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

NSAIDS Following Elective Lumbar Spine Fusion

NCT07743606
View directory record Official record
Conditions
NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion, Ketorolac, Postoperative Pain
Interventions
Ketorolac, Naproxen, Standard Postoperative Pain Management
Drug · Other
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
428 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Not listed Phase 2 Interventional

Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery

NCT00353964
View directory record Official record
Conditions
Ocular Inflammation
Interventions
rEV131, Prenisolone sodium phosphate 1.0%, rEV131 vehicle
Drug
Lead sponsor
Evolutec Group
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
North Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2006 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products

NCT06979804
View directory record Official record
Conditions
ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
Interventions
Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
Device
Lead sponsor
Illinois Center for Orthopaedic Research and Education
Other
Eligibility
16 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Westmont, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Phase 2 Interventional

A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE)

NCT06602453
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
GDC-8264, Placebo
Drug
Lead sponsor
Genentech, Inc.
Industry
Eligibility
40 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Stanford, California • Tampa, Florida • Lutherville, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Results available

Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Adult Participants Undergoing Open-chest Cardiac Surgery (NOVA)

NCT03779841
View directory record Official record
Conditions
Post-Operative Atrial Fibrillation
Interventions
AGN-151607, Placebo
Drug
Lead sponsor
AbbVie
Industry
Eligibility
55 Years to 90 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
19
States / cities
Stanford, California • New Haven, Connecticut • Washington D.C., District of Columbia + 16 more
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 29, 2026, 4:53 AM EDT