- Conditions
- Paget's Disease of Bone
- Interventions
- zoledronic acid, placebo to zoledronic acid, Risedronate, Placebo to risedronate, Calcium and vitamin D supplements
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 30 Years and older
- Enrollment
- 185 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2011
- U.S. locations
- 10
- States / cities
- Tucson, Arizona • Colorado Springs, Colorado • Indianapolis, Indiana + 7 more
Search Results
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Showing 25–43
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- Conditions
- Paget's Disease of Bone
- Interventions
- Zoledronic Acid, Risedronate, Placebo to Risedronate, Placebo to Zoledronic Acid, Calcium and Vitamin D
- Drug · Dietary Supplement
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 30 Years and older
- Enrollment
- 172 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2011
- U.S. locations
- 12
- States / cities
- Santa Monica, California • Lakewood, Colorado • Boca Raton, Florida + 9 more
- Conditions
- Bone Loss
- Interventions
- zoledronic acid, placebo
- Drug
- Lead sponsor
- Thomas J. Schnitzer
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Spinal Cord Injury, Acute Spinal Cord Injury, Bone Loss, Osteoporosis
- Interventions
- Zoledronic acid, Placebo
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 2
- States / cities
- Chicago, Illinois
- Conditions
- Osteoporosis, Bone Loss, Fragility Fractures
- Interventions
- Intravenous zoledronic acid, Vitamin D 800 IU/daily, Calcium 1200 mg/daily
- Drug · Dietary Supplement
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 65 Years and older · Female only
- Enrollment
- 181 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2014
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Prostate Cancer
- Interventions
- zoledronic acid
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 44
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Anchorage, Alaska + 38 more
- Conditions
- Post Menopausal Osteoporosis
- Interventions
- Denosumab, Zoledronic Acid, Placebo to Denosumab, Placebo to Zoledronic Acid
- Biological · Drug
- Lead sponsor
- Amgen
- Industry
- Eligibility
- 55 Years and older · Female only
- Enrollment
- 643 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 9
- States / cities
- Santa Monica, California • Lakewood, Colorado • Longmont, Colorado + 6 more
- Conditions
- Osteoporosis, Post-menopausal
- Interventions
- Teriparatide, Zoledronic Acid
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 55 Years to 89 Years · Female only
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 9
- States / cities
- Lakewood, Colorado • Atlanta, Georgia • Gainesville, Georgia + 6 more
- Conditions
- Post-menopausal Osteoporosis
- Interventions
- Placebo, Zoledronic acid
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 65 Years and older · Female only
- Enrollment
- 190 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 10
- States / cities
- San Diego, California • Lakewood, Colorado • Gainesville, Georgia + 7 more
- Conditions
- Pain, Bone Neoplasm, Neoplasm Metastasis
- Interventions
- ibandronate [Bondronat], zoledronic acid
- Drug
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 163 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 26
- States / cities
- Birmingham, Alabama • Sedona, Arizona • Ocoee, Florida + 22 more
- Conditions
- Sickle Cell Disease
- Interventions
- Placebo, Zoledronic Acid
- Drug
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Cervical Cancer, Precancerous Condition
- Interventions
- Zoledronate, Placebo (Saline)
- Drug · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 120 Years · Female only
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- HIV Infections, Osteopenia, Osteoporosis
- Interventions
- Zoledronate, Zoledronate placebo
- Drug
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Hypercalcemia of Malignancy, Lung Cancer, Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Interventions
- zoledronic acid, quality-of-life assessment
- Drug · Procedure
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2001
- U.S. locations
- 55
- States / cities
- Birmingham, Alabama • Springdale, Arkansas • Gilroy, California + 48 more
- Conditions
- Renal Insufficiency
- Interventions
- Zoledronic Acid, Calcium with vitamin D, Alendronate
- Drug · Combination Product
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2014
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Osteoporosis
- Interventions
- Placebo, Acetaminophen, Fluvastatin
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 45 Years to 79 Years · Female only
- Enrollment
- 793 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- Http://www.osteoporosisclinicalresearch.com, New Jersey
- Conditions
- Bone Loss, Prostate Cancer
- Interventions
- Zoledronic acid, Placebo
- Drug · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2003
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Osteoporosis
- Interventions
- Raloxifene, Zoledronic acid, Placebo oral pills, Placebo intravenous (i.v.) infusion
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 45 Years to 80 Years · Female only
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 17
- States / cities
- Phoenix, Arizona • Buena Park, California • Washington D.C., District of Columbia + 12 more
- Conditions
- Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone Lesions
- Interventions
- Denosumab, Zoledronic acid, Placebo to Denosumab, Placebo to zoledronic acid, Denosumab (for the open-label treatment phase)
- Drug
- Lead sponsor
- Amgen
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,718 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2019
- U.S. locations
- 79
- States / cities
- Tucson, Arizona • Fayetteville, Arkansas • Anaheim, California + 67 more