- Conditions
- Hidradenitis Suppurativa (HS)
- Interventions
- Botulinum Toxin A (Allergan, Inc, Irvine CA), Placebo
- Drug
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 13 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
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Showing 25–48
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- Conditions
- Neuromuscular Agents, Peripheral Nervous System Agents, Physiological Effects of Drugs, Acetylcholine Release Inhibitors, Membrane Transport Modulators, Molecular Mechanisms of Pharmacological Action, Cholinergic Agents, Neurotransmitter Agents, incobotulinumtoxinA, Botulinum Toxins, Type A
- Interventions
- NT 201, NT 201 Placebo
- Drug
- Lead sponsor
- Merz North America, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 27
- States / cities
- Scottsdale, Arizona • Encino, California • Los Angeles, California + 22 more
- Conditions
- Scleroderma, Raynaud's Syndrome
- Interventions
- Onabotulinumtoxin A, sterile saline solution
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Forehead Rhytides, Glabellar Rhytides
- Interventions
- OnabotulinumtoxinA, Normal Saline
- Biological · Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 421 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 9
- States / cities
- Birmingham, Alabama • Glendale, Arizona • Santa Monica, California + 6 more
- Conditions
- Moderate to Severe Glabellar Frown Lines
- Interventions
- IncobotulinumtoxinA (Xeomin) (20 Units), Placebo
- Drug
- Lead sponsor
- Merz Pharmaceuticals GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 271 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 8
- States / cities
- Englewood, Colorado • Aventura, Florida • Coral Gables, Florida + 5 more
- Conditions
- Overactive Bladder
- Interventions
- botulinum toxin Type A, Normal Saline (Placebo)
- Biological · Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Glabellar Lines
- Interventions
- AGN-151586, OnabotulinumtoxinA, Placebo
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 8
- States / cities
- Scottsdale, Arizona • Newport Beach, California • Redondo Beach, California + 5 more
- Conditions
- Urinary Incontinence
- Interventions
- Botox, Placebo
- Drug
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 21 Years to 90 Years · Female only
- Enrollment
- 31 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2011
- U.S. locations
- 3
- States / cities
- Sacramento, California • Boston, Massachusetts • Durham, North Carolina
- Conditions
- Stroke With Hemiparesis
- Interventions
- Botulinum Toxin commonly known as BOTOX®, Placebo
- Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Moderate to Severe Glabellar Frown Lines
- Interventions
- IncobotulinumtoxinA (Xeomin) (20 Units), Placebo
- Drug
- Lead sponsor
- Merz Pharmaceuticals GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 276 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Meatrie, Louisiana • Chestnut Hill, Massachusetts + 2 more
- Conditions
- Platysmal Bands
- Interventions
- AbobotulinumtoxinA dose 1, Placebo, AbobotulinumtoxinA dose 2, AbobotulinumtoxinA dose 3
- Biological · Other
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 8
- States / cities
- Encinitas, California • Encino, California • Boynton Beach, Florida + 4 more
- Conditions
- Hallux Abducto Valgus
- Interventions
- Botulinum toxin type A, Placebo
- Biological · Drug
- Lead sponsor
- Ipsen
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 186 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 29
- States / cities
- Jonesboro, Arkansas • Little Rock, Arkansas • Castro Valley, California + 25 more
- Conditions
- Glabellar Rhytides
- Interventions
- Preservative-free Saline, Mentor Purified Toxin
- Drug
- Lead sponsor
- Mentor Worldwide, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 402 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Santa Barbara, California
- Conditions
- Cervical Dystonia
- Interventions
- Botulinum toxin type A, Placebo
- Biological · Drug
- Lead sponsor
- Ipsen
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 18
- States / cities
- Phoenix, Arizona • Fountain Valley, California • Los Angeles, California + 14 more
- Conditions
- Post-Operative Atrial Fibrillation
- Interventions
- AGN-151607, Placebo
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 55 Years to 90 Years
- Enrollment
- 323 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 19
- States / cities
- Stanford, California • New Haven, Connecticut • Washington D.C., District of Columbia + 16 more
- Conditions
- Endometriosis, Chronic Pelvic Pain, Pelvic Muscle Spasm, Quality of Life
- Interventions
- Botulinum toxin (BoNT), Placebo
- Drug
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 18 Years to 55 Years · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Ventral Hernia, Abdominal Hernia
- Interventions
- BOTOX Dose A, Placebo for BOTOX, BOTOX Dose B, BOTOX Dose C
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 18 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 2
- States / cities
- Mineola, New York • Charlotte, North Carolina
- Conditions
- Skin Aging
- Interventions
- Botulinum toxin type A, Placebo comparator
- Biological
- Lead sponsor
- Revance Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Coral Gables, Florida
- Conditions
- Upper Limb Spasticity
- Interventions
- ABBV-950, BOTOX, Placebo for ABBV-950
- Biological · Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 9
- States / cities
- Carlsbad, California • Downey, California • Fresno, California + 6 more
- Conditions
- Pain
- Interventions
- Botulinum Toxin Type A, Saline
- Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Spasticity
- Interventions
- Corabotase, Placebo, Dysport
- Biological · Drug
- Lead sponsor
- Ipsen
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2029
- U.S. locations
- 5
- States / cities
- Downey, California • Overland Park, Kansas • Farmington Hills, Michigan + 2 more
- Conditions
- Chronic Migraine
- Interventions
- Xeomin, Placebo
- Drug
- Lead sponsor
- Merz Therapeutics GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 780 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 48
- States / cities
- Chandler, Arizona • Phoenix, Arizona • Little Rock, Arkansas + 42 more
- Conditions
- Stroke, Muscle Spasticity
- Interventions
- Botox (botulinum toxin)
- Drug
- Lead sponsor
- New York Presbyterian Hospital
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cervical Dystonia
- Interventions
- ABP-450, Placebo
- Drug
- Lead sponsor
- AEON Biopharma, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 21
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Fountain Valley, California + 17 more