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ClinicalTrials.gov public records Last synced Oct 28, 2026, 4:15 AM EDT

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Showing 673–696 of 1,719 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Positive control Clear all
Completed Phase 1Phase 2 Interventional Results available

Sirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer

NCT00311623
View directory record Official record
Conditions
Prostate Cancer
Interventions
Rapamycin 3mg, Rapamycin 6mg, Radical prostatectomy
Drug · Procedure
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Baltimore, Maryland • Ann Arbor, Michigan • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 28, 2026, 4:15 AM EDT
Active, not recruiting Not applicable Interventional

A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors

NCT06153797
View directory record Official record
Conditions
Hematologic Malignancy, Caregiver
Interventions
PATH-C
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional

A Comparison of Interventions to Teach Melanoma Patients Skin Self-examination

NCT01432860
View directory record Official record
Conditions
Melanoma
Interventions
In-person counseling, Workbook, Tablet Computer-Based Education
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional Results available

High Flow Therapy for the Treatment of Respiratory Failure in the ED

NCT02236559
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Noninvasive positive pressure ventilation (NIPPV), Vapotherm
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
5
States / cities
Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Early Phase 1 Interventional Results available

Role of Methane in Glycemic Control

NCT01638429
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Neomycin, Rifaximin
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional

Diabetes Survival Skills + (DSS+) Training Intervention for Incarcerated Persons Transitioning to the Community (TTC)

NCT05510531
View directory record Official record
Conditions
Diabetes
Interventions
Diabetes Survival Skills Training
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older · Male only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Phase 1 Interventional

Autologous Dendritic Cells Pulsed With Autologous Apoptotic Tumor Cells Administered to Patients With Brain Tumors

NCT00893945
View directory record Official record
Conditions
Brain Tumors
Interventions
DC/AAT, DC/AAT-Flu, DC/KLH
Drug
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2014 · Synced Oct 28, 2026, 4:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth

NCT06109766
View directory record Official record
Conditions
Parenting, Parent-Child Relations, Child Behavior, Child Maltreatment
Interventions
Promoting First Relationships
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Phase 2 Interventional Results available

A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection

NCT03576066
View directory record Official record
Conditions
Chronic Hepatitis B
Interventions
ABI-H0731, SOC NUC, Placebo Oral Tablet
Drug
Lead sponsor
Assembly Biosciences
Industry
Eligibility
18 Years to 70 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
17
States / cities
Beverly Hills, California • Coronado, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional

Contingency Management for Drug Use: Does Age Matter?

NCT05521854
View directory record Official record
Conditions
Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
Interventions
DynamiCare app (app-based contingency management), Sham control
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Active, not recruiting Not applicable Interventional

Culturally Adapted RUBI for Spanish-Speaking Families in Texas and Mexico

NCT07185737
View directory record Official record
Conditions
Autism
Interventions
Adapted RUBI-Telehealth
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Assess the Cardiac Safety of Oritavancin in Healthy Participants

NCT01762839
View directory record Official record
Conditions
Healthy
Interventions
Single-Dose IV Oritavancin Diphosphate, Placebo, Moxifloxacin
Drug
Lead sponsor
Melinta Therapeutics, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 28, 2026, 4:15 AM EDT
Not listed Not applicable Interventional

Extralevator Versus Standard Abdominoperineal Resection For Rectal Adenocarcinoma

NCT01702116
View directory record Official record
Conditions
Rectal Adenocarcinoma
Interventions
extralevator APR, APR
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Oct 28, 2026, 4:15 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

SV2 PET Imaging With [11C]APP311

NCT03995121
View directory record Official record
Conditions
Schizophrenia and Other Psychotic Disorders, Cannabis Use Disorder, Healthy
Interventions
[11C]APP311
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

NCT03488927
View directory record Official record
Conditions
Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression, Alcohol Abuse, Drinking, College, Alcohol Drinking, Alcohol; Harmful Use, Social Stigma, Social Norms, Social Responsibility, Social Behavior, Empathy, Coping Skills, Coping Behavior
Interventions
Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 24 Years
Enrollment
1,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 28, 2026, 4:15 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Testing Ultra-processed Warning Labels and Not-Ultra-processed Labels in United States

NCT07863570
View directory record Official record
Conditions
Ultra-processed Labels
Interventions
NIB: Label exposure in mock-up UPF and Not-UPF products, NIB+UPFWL: Label exposure in mock-up UPF and Not-UPF products, NIB+Not-UPF Black: Label exposure in mock-up UPF and Not-UPF products, NIB+Not-UPF Green: Label exposure in mock-up UPF and Not-UPF products
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
12,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining Variation in the Impact of School-Wide Positive Behavioral Interventions and Supports (PBIS)

NCT01583127
View directory record Official record
Conditions
Problem Behavior
Interventions
Positive Behavioral Interventions & Supports
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
5 Years and older
Enrollment
32,986 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 28, 2026, 4:15 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)

NCT04845542
View directory record Official record
Conditions
Stroke, Depression, Anxiety, Coping Skills, Couples
Interventions
ReStoreD
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Safety Study of Hepatitis E Vaccine (HEV239)

NCT03827395
View directory record Official record
Conditions
Hepatitis E, Immunisation
Interventions
HEV 239, Placebo
Biological · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Melanoma Simulation Model With Smartphone Devices: Training Physicians for Early Detection of Melanoma

NCT01859845
View directory record Official record
Conditions
Melanoma
Interventions
Smartphone
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 28, 2026, 4:15 AM EDT
Recruiting Phase 3 Interventional

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

NCT04678154
View directory record Official record
Conditions
Post Operative Surgical Site Infection
Interventions
Standard of care, Vancomycin and Tobramycin
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 64 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
31
States / cities
Redwood City, California • San Francisco, California • Aurora, Colorado + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study of Valortim® (MDX-1303) and Its Selected Formulation Components Percutaneous Use

NCT01204866
View directory record Official record
Conditions
Allergic Reactions
Interventions
Valortim and selected Components, Valortim and Selected Components
Biological · Drug
Lead sponsor
PharmAthene, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2010 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Phase 3 Interventional Results available

Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase Inhibitor

NCT01610284
View directory record Official record
Conditions
Breast Cancer
Interventions
Fulvestrant, BKM120, BKM120 matching placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
61
States / cities
Mobile, Alabama • Phoenix, Arizona • Fayetteville, Arkansas + 51 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 28, 2026, 4:15 AM EDT
Completed Not applicable Interventional

Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing

NCT02514798
View directory record Official record
Conditions
COPD
Interventions
Esophageal and gastric balloons, Respiratory Inductance Plethysmography (RIP) system, Sentec transcutaneous monitoring system, High-flow humidified nasal oxygen delivery system, CPAP (Positive Control)
Other · Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 28, 2026, 4:15 AM EDT