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ClinicalTrials.gov public records Last synced Nov 8, 2026, 4:35 AM EST

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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Regional manual therapy Clear all

Conditions: Post Traumatic Stress Disorder
Interventions: Active rTMS, Sham rTMS, Cognitive Processing Therapy; Device · Behavioral
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 60 Years
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 3
States / cities: Tallahassee, Florida • Addison, Texas • Dallas, Texas

Conditions: Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke
Interventions: Beating the Blues (BtB), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Usual Care; Behavioral · Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 50 Years and older
Enrollment: 216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Cystic Fibrosis
Interventions: BMI and lean mass index from DXA, Anthropometric Measurements, Hand-grip strength, Six-minute walk Test, Sit-to-Stand Test, Short physical performance battery (SPPB), BIA Sub-study, Accelerometry to assess physical activity, Gastrointestinal (GI) and nutrition questionnaires:, Psychosocial questionnaire: PHQ-8, Psychosocial questionnaire: GAD-7, Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ), Psychosocial questionnaire: CF Fatalism Scale, Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA), 12-month Questionnaire, Oral glucose tolerance testing (OGTT), Continuous glucose monitoring (CGM), Chest CT scans (When available within the past 6 months in medical records), Hologic Dual X-Ray Absorptiometry (DXA), Ultrasound Sub-study of assessment of appendage muscles using ultrasound, Psychosocial questionnaire: Hunger Vital Sign questionnaire, Respiratory symptom questionnaire: CRISS, Spirometry, Psychosocial questionnaire: Additional Health Questionnaire, CF Management Questionnaire, Food Frequency Questionnaire; Diagnostic Test · Other · Device
Lead sponsor: Jaeb Center for Health Research; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 23
States / cities: Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more

Conditions: Urinary Incontinence
Interventions: UI-Assist, Partnership Building; Behavioral · Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 3
States / cities: San Diego, California • Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Shoulder Adhesive Capsulitis
Interventions: Home based FES in combination with usual therapy; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Gastroesophageal-junction Cancer, Esophageal Cancer
Interventions: EORTC QLQ-C30 questionnaire, QLQ-OGS25 questionnaire; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Use, Sexual Risk Behaviors
Interventions: Risk Reduction Therapy for Adolescents, Usual services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Knee Osteoarthritis
Interventions: Duloxetine, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices; Drug · Combination Product · Procedure + 2 more
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1,937 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 24
States / cities: Sacramento, California • San Diego, California • Aurora, Colorado + 19 more

Conditions: Persistent Pregnancy of Unknown Location, Ectopic Pregnancy
Interventions: Methotrexate, Uterine Evacuation, Expectant Management; Drug · Procedure · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 255 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 17
States / cities: San Francisco, California • Denver, Colorado • New Haven, Connecticut + 13 more

Conditions: Pain, Spasticity, Muscle, Quality of Life
Interventions: Counterstrain manual manipulative treatment; Other
Lead sponsor: William Carey University; Other
Eligibility: 21 Years to 70 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Hattiesburg, Mississippi

Conditions: Persistent Pregnancy of Unknown Location, Ectopic Pregnancy
Interventions: Methotrexate, Uterine Evacuation, Expectant Management; Drug · Procedure · Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older · Female only
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Greenville, South Carolina

Conditions: Lymphedema, Breast Cancer
Interventions: Surgical Intervention, Conservative Complex Physical Decongestion Therapy; Procedure
Lead sponsor: University Hospital, Basel, Switzerland; Other
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2036
U.S. locations: 4
States / cities: New Haven, Connecticut • Boston, Massachusetts • Rochester, Minnesota + 1 more

Conditions: Chronic Tendinopathy
Interventions: Adipose Stem/Stromal Cells for Enthesis/Tendon Therapy (ASSET) Injection; Procedure
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Pelvic Pain, Chronic Pain, Muscle Tightness
Interventions: Orthopedic Physical Therapy Intervention, Dry Needling; Procedure · Device
Lead sponsor: Texas Woman's University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Lee's Summit, Missouri

Conditions: Shoulder Pain
Interventions: First Rib Mobilization, Sham Comparator; Other
Lead sponsor: Andrews University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Annville, Pennsylvania

Conditions: Neck Pain, Back Pain
Interventions: Indocyanine green (ICG) dye, NIRF-LI imaging, Neuroglide pad; Drug · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Stage IB2 Cervical Cancer FIGO 2018, Stage IB3 Cervical Cancer FIGO 2018, Stage II Cervical Cancer FIGO 2018, Stage IIA Cervical Cancer FIGO 2018, Stage IIA1 Cervical Cancer FIGO 2018, Stage IIA2 Cervical Cancer FIGO 2018, Stage IIB Cervical Cancer FIGO 2018, Stage IIIA Cervical Cancer FIGO 2018, Stage IIIB Cervical Cancer FIGO 2018
Interventions: Media Intervention, Quality-of-Life Assessment, Questionnaire Administration, Survey Administration, Yoga; Other · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Soft Tissue Approximation, Elevation of Subdermis, Elevation of Underlying Muscle
Interventions: MyEllevate Procedure; Device
Lead sponsor: Cynosure, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Montclair, New Jersey • Staten Island, New York

Conditions: Rheumatoid Arthritis, Arthritis
Interventions: Yoga; Behavioral
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Elbow Injuries and Disorders, Neuritis, Ulnar, Neuritis, Brachial, Neuritis; Nerve Root, Neuritis Median Nerve
Interventions: Rehabiltiation using exercise and manual therapy; Other
Lead sponsor: Timothy Uhl; Other
Eligibility: 15 Years to 50 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Lumbar Spinal Stenosis
Interventions: NSAIDs; adjunctive analgesics; adjunctive anti-depressants, Lumbar epidural injection, Joint Mobilizations (spine, sacroiliac, hip), Individualized exercises: clinical setting, Group Exercise: community setting; Drug · Procedure · Other
Lead sponsor: Michael Schneider, DC, PhD; Other
Eligibility: 60 Years and older
Enrollment: 259 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Tissue Pain
Interventions: Soft tissue manipulation; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Low Back Pain
Interventions: Patient Education, Manual therapy of the thoracolumbosacral spine and hips, Motor control exercises, Treatment-Based Classification intervention; Behavioral · Procedure
Lead sponsor: Hendricks Regional Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Plainfield, Indiana

Conditions: Depression
Interventions: Enhanced BHL Program Services, Standard BHL Program Services; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 65 Years and older
Enrollment: 2,432 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Search by objective public record fields.

Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD

eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients

Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF

WI-INTUIT: Bridging Community Based Continence Promotion and Primary Care

Feasibility, Usability and Preliminary Efficacy of Home-based FES Fro Adhesive Capsulitis

Registry for Esophageal and Gastroesophageal Junction Cancer

Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth

A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

Optimal Treatment for Women With a Persisting Pregnancy of Unknown Location

Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI

RCT for Women With a Persisting Pregnancy of Unknown Location

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

Autologous Fat Grafting for the Treatment of Chronic Tendinopathy

The Effect of an Individualized Impairment-based, Orthopedic Physical Therapy Intervention (IOI), on Muscle Stiffness, Pelvic Floor Function, and Pain in Women With Chronic Pelvic Pain

The Immediate Effects of First Rib Mobilization on Pain and Range of Motion in Patients With Shoulder Pain

Near-infrared Fluorescence Lymphatic Imaging Assessment of Lymphatic Response to Pneumatic Back/Neck Lymphatic Drainage Delivered by a Pneumatic Manual Lymphatic Drainage Device

Yoga Therapy During Chemotherapy and Radiation Treatment for the Improvement of Physical and Emotional Well-Being in Patients With Stage IB2-IIIB Cervical Cancer

Study To Evaluate The Safety And Efficacy Of The MyEllevate® Procedure

Yoga as Self-Care for Arthritis in Minority Communities

Physical Therapy on Non-structural Medial Elbow Pain

Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)

Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness

A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain

The PACE/PACENET Behavioral Health Laboratory Project