Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 5, 2026, 4:39 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 589 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: SIGNAL Clear all

Conditions: Metastatic Castration Sensitive Prostate Cancer
Interventions: Luteinizing Hormone-Releasing Hormone (LHRH) analog, Androgen Receptor Signal Inhibitor (ARSI), Docetaxel; Drug
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older · Male only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: BRAF V600E Mutation
Interventions: Dabrafenib Mesylate, Trametinib Dimethyl Sulfoxide; Drug
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Heart Failure, Medication Compliance
Interventions: PROTEUS-SENSOR; Device
Lead sponsor: Scripps Translational Science Institute; Other
Eligibility: Not listed
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: IDH Wild Type Glioblastoma
Interventions: ¹⁸F-Fluoromisonidazole, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Oxygen Therapy, Ferumoxytol, Gadolinium; Drug · Procedure
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2030
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Attention Deficit Hyperactivity Disorder (ADHD), Sleep, Physical Activity
Interventions: Go/No-Go Task, Delay discounting task, Mirror Tracing Persistence Task, Spatial Span, Stop Signal Task, Flanker task; Behavioral
Lead sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; Other
Eligibility: 8 Years to 12 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2031
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Postoperative Nausea and Vomiting, Bariatric Sleeve Gastrectomy
Interventions: Wearable Transcutaneous electrical Nerve Stimulation unit to mitigate postoperative nausea and vomiting (PONV) in the Bariatric Surgical Patient, A sham device that will mimic the active wearable device. It will look the same, and buzz but will not actually admit a low-leve electric current that would stimulate the nerves.; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Plainsboro, New Jersey

Conditions: Speech Sound Disorder
Interventions: Visual-acoustic biofeedback, Motor-based treatment; Behavioral
Lead sponsor: New York University; Other
Eligibility: 9 Years to 15 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Bloomfield, New Jersey • Syracuse, New York

Conditions: Spinal Cord Injuries, Respiratory Complication
Interventions: Jamboxx Respiratory Therapy Device, Jamboxx Musical Device; Device
Lead sponsor: My Music Machines Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Albany, New York

Conditions: Atrial Fibrillation, Afib, ECG
Interventions: ECG co-measurement; Device
Lead sponsor: TriVirum, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: San Diego, California

Conditions: Attention Deficit Hyperactivity Disorder
Interventions: Adaptive Inhibitory Control Training, Non-adaptive Inhibitory Control Training; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 8 Years to 11 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Knee
Interventions: Orthofix Physio-Stim Model 3315OA; Device
Lead sponsor: Orthofix Inc.; Industry
Eligibility: 40 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Baltimore, Maryland • Cleveland, Ohio

Conditions: Lymphoma
Interventions: rituximab, clofarabine, DNA methylation analysis, gene expression analysis, microarray analysis, polymerase chain reaction, high performance liquid chromatography, laboratory biomarker analysis; Biological · Drug · Genetic + 1 more
Lead sponsor: OHSU Knight Cancer Institute; Other
Eligibility: 18 Years to 89 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Carotid Stenosis
Interventions: Bilateral carotid Doppler signal acquisition (Vibrant Stroke Detection Technology); Device
Lead sponsor: Vibrant Medical Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Electrode Site Reaction
Interventions: RM Electrode, ERG Jet Electrode; Device
Lead sponsor: RetMap, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Stroke, Hand Weakness
Interventions: NoNo, occupational therapy - self directed; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Stroke
Interventions: IpsiHand Device; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 88 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Brain Concussion, Mild Traumatic Brain Injury
Interventions: BrainPulse; Device
Lead sponsor: Jan Medical, Inc.; Industry
Eligibility: 5 Years and older
Enrollment: 406 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 3
States / cities: Boston, Massachusetts • Cincinnati, Ohio • Johnson City, Tennessee

Conditions: Withdrawal Symptoms, Opioid Use Disorder, Opioid Use
Interventions: Transcutaneous Cervical Vagal Nerve Stimulation, Sham Stimulation, [F-18]Fallypride; Device · Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 6
States / cities: Atlanta, Georgia

Conditions: Chronic Insomnia
Interventions: Not listed
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Knee Injuries, Shoulder Injuries, Pain, Postoperative
Interventions: Endonovo SofPulse; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Chronic Stroke
Interventions: motor learning based therapy, MyoPro, Home Exercise Program; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Metastatic Melanoma, Squamous Cell Carcinoma of the Head and Neck, Non-small Cell Lung Cancer
Interventions: Lifileucel, LN-145, Pembrolizumab, LN-145-S1, Ipilimumab, Nivolumab, Nivolumab-relatlimab, Cisplatin, Carboplatin, Paclitaxel, Nab paclitaxel, Pemetrexed; Biological · Drug
Lead sponsor: Iovance Biotherapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 20
States / cities: La Jolla, California • Los Angeles, California • Denver, Colorado + 15 more

Conditions: Atrial Fibrillation
Interventions: Facial video of detection of cardiac disease; Diagnostic Test
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Spinal Cord Injury
Interventions: Exoskeleton-Assisted Walking (EAW), Sham Transcutaneous Spinal Cord Stimulation (tSCS), Active Transcutaneous Spinal Cord Stimulation (tSCS); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 60 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 2
States / cities: West Orange, New Jersey • The Bronx, New York

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Adaptive Androgen Deprivation and Docetaxel in Metastatic Castration Sensitive Prostate Cancer

Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

Monitoring Medication Adherence in Left Ventricular Assist Device Recipients

Feasibility of FMISO in Brain Tumors

Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD

Use of Transcutaneous Electrical Nerve Stimulation Device, Reletex Reliefband, With Current ERAS (Enhanced Recovery After Surgery) Protocol to Further Decrease Postoperative Nausea and Vomiting in the Bariatric Surgical Patient Within the First 24 Hours Postoperatively.

Comparing Traditional and Biofeedback Telepractice Treatment for Residual Speech Errors

Effectiveness of Jamboxx Respiratory Therapy Device: Study 1

Clinical Performance of AFGen1

Neuroplasticity Technology for Attention-deficit/Hyperactivity Disorder (ADHD)

Efficacy and Safety of an Active Pulsed Electromagnetic Field for the Treatment of Osteoarthritis of the Knee

Clofarabine and Rituximab in Treating Patients With Relapsed Non-Hodgkin Lymphoma

A First-in-Human Feasibility Study of the Vibrant Stroke Detection Technology During Carotid Endarterectomies

Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects

Self-Administered Gaming and Exercise at Home (SAGEH)

Treatment of Chronic Stroke With IpsiHand

Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

Hyper-Arousal in Chronic Primary Insomnia

Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery

Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Video-based Detection of Atrial Fibrillation

Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.