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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:37 AM EDT

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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Screening digital breast tomosynthesis Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Early Detection of Breast Cancer Using Tomosynthesis Imaging

NCT00637598
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Mammography and tomosynthesis imaging
Radiation
Lead sponsor
Duke University
Other
Eligibility
Female only
Enrollment
385 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational

Simulated Screening Study for Breast Imaging

NCT01807754
View directory record Official record
Conditions
Breast Cysts, Breast Tumors
Interventions
X-ray and ultrasound imaging scanning, Photoacoustic imaging scans for breast cancer screening
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
30 Years to 80 Years · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational

Clinical Utility of Whole Breast Screening Ultrasound in Patients Undergoing Digital Breast Tomosynthesis

NCT02174406
View directory record Official record
Conditions
Breast Screening
Interventions
breast ultrasound, DBT (Full field digital mammography + tomosynthesis)
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
30 Years and older · Female only
Enrollment
1,494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 23, 2023 · Synced Oct 19, 2026, 10:37 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Biennial CEM in Women With a Personal History of Breast Cancer

NCT06105749
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms, Breast Cancer Female, Neoplasms
Interventions
contrast-enhanced mammography
Device
Lead sponsor
Wendie Berg
Other
Eligibility
30 Years to 79 Years · Female only
Enrollment
1,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2031
U.S. locations
6
States / cities
Bethel Park, Pennsylvania • Cranberry Township, Pennsylvania • Monroeville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Acquisition of Breast Mammography Images

NCT02156258
View directory record Official record
Conditions
Breast Cancer
Interventions
FFDM Mammography, DBT Mammography
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
5
States / cities
Scottsdale, Arizona • Iowa City, Iowa • Rochester, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Oct 19, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

Multicenter Hologic Tomosynthesis Study

NCT00971087
View directory record Official record
Conditions
Breast Cancer
Interventions
Hologic Selenia Dimensions Digital Breast Tomosynthesis System
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 110 Years · Female only
Enrollment
3,521 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
22
States / cities
Scottsdale, Arizona • Newport Beach, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multi-Reader, Multi-Case, Cross-Over, Retrospective Study to Evaluate Effectiveness of Lunit INSIGHT DBT

NCT05716958
View directory record Official record
Conditions
Breast Cancer
Interventions
Digital Breast Tomosynthesis
Radiation
Lead sponsor
Lunit Inc.
Industry
Eligibility
22 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 19, 2026, 10:37 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

B.Brilliant Revelation Comparision Study

NCT07067788
View directory record Official record
Conditions
Breast Cancer Screening
Interventions
Breast Imaging
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 19, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates

NCT01236781
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Screening Tomosynthesis, Diagnostic Tomosynthesis
Device
Lead sponsor
American College of Radiology
Other
Eligibility
25 Years and older · Female only
Enrollment
558 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Delphinus SoftVue Prospective Case Collection - ARM 1

NCT03257839
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Routine Full-Field Digital Mammography, Routine Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound
Device
Lead sponsor
Delphinus Medical Technologies, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
7,409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
10
States / cities
Los Angeles, California • Miami Beach, Florida • Savannah, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 19, 2026, 10:37 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Automated Breast Ultrasound and Digital Breast Tomosynthesis Screening Compared to Full Field Digital Mammography in Women With Dense Breasts

NCT02042456
View directory record Official record
Conditions
Breast Cancer
Interventions
Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound, Full Field Digital Mammography
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older · Female only
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational

Testing Digital Breast Tomosynthesis vs. Regular Mammogram in Detecting Breast Cancer in Women Having Screening Mammogram

NCT00535678
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 14, 2010 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational

Delphinus SoftVue Prospective Case Collection - ARM 2

NCT02977247
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Non-Interventional, Automated Whole Breast Ultrasound
Other · Device
Lead sponsor
Delphinus Medical Technologies, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
10
States / cities
Los Angeles, California • Miami Beach, Florida • Savannah, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 19, 2026, 10:37 AM EDT
Completed Early Phase 1 Interventional

A Comparison of Breast Tomosynthesis Mammography and Conventional Breast Imaging in the Characterization of Breast Masses

NCT00826488
View directory record Official record
Conditions
Fibrocystic Disease of Breast, Breast Cancer
Interventions
Digital Breast Tomosynthesis
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 80 Years · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Collection of FUJIFILM's 3Dimensional Mammograms

NCT01542814
View directory record Official record
Conditions
Breast Cancer
Interventions
3Dimensional Mammography, 2D FFDM
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
40 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
3
States / cities
Scottsdale, Arizona • Atlanta, Georgia • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 25, 2013 · Synced Oct 19, 2026, 10:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Digital Breast Tomosynthesis (DBT) in the Screening Environment

NCT01106911
View directory record Official record
Conditions
Breast Abnormalities
Interventions
tomosynthesis and screening mammography
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
35 Years to 55 Years · Female only
Enrollment
1,080 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2016 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Breast Cancer Screening for Underserved Women: Comparing Outcomes and Lowering Recall Rates With 3D- vs. 2D-mammography

NCT03979729
View directory record Official record
Conditions
Breast Cancer Screening
Interventions
Routine Screening Mammogram (3D + 2D), Routine Screening Mammogram (2D), No Screening Mammogram
Other
Lead sponsor
New Mexico Cancer Research Alliance
Other
Eligibility
40 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Oct 19, 2026, 10:37 AM EDT
Recruiting Phase 2 Interventional

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

NCT05941520
View directory record Official record
Conditions
Breast Atypical Hyperplasia, Breast Carcinoma, Breast Ductal Carcinoma In Situ, Breast Lobular Carcinoma In Situ
Interventions
Acolbifene Hydrochloride, Biospecimen Collection, Mammography, Questionnaire Administration, Random Periareolar Fine-Needle Aspiration, Tamoxifen
Drug · Procedure · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
35 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Duarte, California • Chicago, Illinois • Kansas City, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 19, 2026, 10:37 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania

NCT04085510
View directory record Official record
Conditions
Breast Cancer Female, Breast Cancer, Breast Neoplasms, Neoplasms
Interventions
Contrast-enhanced mammogram
Device
Lead sponsor
Wendie Berg
Other
Eligibility
30 Years to 85 Years · Female only
Enrollment
1,647 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
3
States / cities
Cranberry Township, Pennsylvania • Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 19, 2026, 10:37 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts

NCT02933489
View directory record Official record
Conditions
Asymptomatic
Interventions
Contrast-enhanced Magnetic Resonance Imaging, Digital Tomosynthesis Mammography, Quality-of-Life Assessment, Questionnaire Administration
Diagnostic Test · Other
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
40 Years to 75 Years · Female only
Enrollment
1,516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
67
States / cities
Gilbert, Arizona • Pasadena, California • Denver, Colorado + 54 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 19, 2026, 10:37 AM EDT
Completed No phase listed Observational

Development Of A Blood Test To Improve The Performance Of Breast Cancer Screening

NCT03372902
View directory record Official record
Conditions
Breast Cancer, Breast Benign
Interventions
Breast MRI, Breast Mammogram, Blood draw, Breast Biopsy, online participant reported questionnaire
Device · Other · Procedure + 1 more
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
628 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
7
States / cities
Hartford, Connecticut • Miami, Florida • Basking Ridge, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2025 · Synced Oct 19, 2026, 10:37 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acquisition and Clinical Image Evaluation of Fujifilm's High Resolution (HR) Digital Breast Tomosynthesis (DBT) Images.

NCT07471750
View directory record Official record
Conditions
Routine Screening Mammography
Interventions
DBT HR mode image acquisition
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
40 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 19, 2026, 10:37 AM EDT
Not listed No phase listed Observational

Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study

NCT02980848
View directory record Official record
Conditions
Breast Cancer
Interventions
Screening digital mammography, Screening digital breast tomosynthesis, Screening breast magnetic resonance imaging, Diagnostic mammography, Pre-operative breast magnetic resonance imaging
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
1,341,172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
7
States / cities
Davis, California • San Francisco, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2021 · Synced Oct 19, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

Contrast-Enhanced Mammography for Breast Cancer Staging in Patients Referred for a Second Opinion

NCT05036083
View directory record Official record
Conditions
Breast Carcinoma, Invasive Breast Carcinoma
Interventions
Contrast-Enhanced Mammography, Digital Tomosynthesis Mammography, Electronic Health Record Review, Iodinated Contrast Agent
Procedure · Other · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 19, 2026, 10:37 AM EDT