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ClinicalTrials.gov public records Last synced Nov 14, 2026, 6:11 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 457–480 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Sepsis
Interventions: PRESS Intervention; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 984 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 3
States / cities: Atlanta, Georgia • Iowa City, Iowa • St Louis, Missouri

Conditions: Severe Sepsis, Severe Sepsis Without Septic Shock
Interventions: Not listed
Lead sponsor: Beckman Coulter, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 40,000 participants
Timeline: 2021 – 2026
U.S. locations: 10
States / cities: Irvine, California • Augusta, Georgia • Indianapolis, Indiana + 6 more

Conditions: Artifical Inteligence, Cardiology, Breast Cancer, Sepsis
Interventions: AI-PERSONALIZED CLINICAL DECISION SUPPORT; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older
Enrollment: 300,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Severe Sepsis
Interventions: Talactoferrin alfa, Placebo; Drug
Lead sponsor: Agennix; Industry
Eligibility: 18 Years and older
Enrollment: 1,280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 34
States / cities: Birmingham, Alabama • Mobile, Alabama • Maricopa, Arizona + 31 more

Conditions: Maternal Sepsis, Infections
Interventions: Maternal Sepsis Safety Bundle; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: Female only
Enrollment: 33,183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: New York, New York • The Bronx, New York

Conditions: Enterococcal Bacteremia
Interventions: Not listed
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 8
States / cities: Miami, Florida • Detroit, Michigan • Jackson, Mississippi + 4 more

Conditions: Infection, Bacteremia
Interventions: Telavancin; Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sepsis
Interventions: Blood sample collection; Other
Lead sponsor: University of British Columbia; Other
Eligibility: 19 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sepsis
Interventions: Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples; Procedure · Drug · Device + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Neonatal Early-onset Sepsis, Neonatal Late-onset Sepsis
Interventions: Intervention is to stop antibiotics at 24h .; Other
Lead sponsor: Yale University; Other
Eligibility: 1 Hour to 5 Months
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Sepsis, Sepsis, Severe, Septic Shock
Interventions: Sepsis care bundle; Other
Lead sponsor: HealthPartners Institute; Other
Eligibility: 18 Years to 100 Years
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Stillwater, Minnesota

Conditions: Severe Sepsis or Septic Shock
Interventions: Calcitriol, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Staphylococcus Aureus
Interventions: AZD7760, Placebo; Drug · Other
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 242 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 40
States / cities: Huntsville, Alabama • Chula Vista, California • Glendale, California + 35 more

Conditions: Staphylococcus Aureus
Interventions: Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization; Drug
Lead sponsor: Harvard Pilgrim Health Care; Other
Eligibility: Not listed
Enrollment: 353,323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 137
States / cities: Riverside, California • San Jose, California • Thousand Oaks, California + 103 more

Conditions: Sepsis
Interventions: Muscle stimulation with Niveus medical stimulator, measurement of maximal isometric twitch strength, Muscle Biopsy, Muscle Biopsy Medication: Lidocaine, Muscle Biopsy Medication: Versed, Muscle Biopsy Medication: Fentanyl, Blood and Urine Sampling, ineffective muscle stimulation; Device · Procedure · Drug + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Sterile Catheter, Catheter-related Bloodstream Infections, Dialysis Catheter, Dialysis
Interventions: Catheter Caps Case (C3); Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Hypothermia
Interventions: placement of plastic cap during delivery room stabilization, placement of routine cap during delivery room stabilization; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: Up to 1 Hour
Enrollment: 260 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Sepsis
Interventions: Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics, Mobility Monitors; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions: Ampicillin, Gentamycin, Normal saline; Drug
Lead sponsor: Michael Morowitz; Other
Eligibility: Up to 4 Hours
Enrollment: 359 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 14
States / cities: Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more

Conditions: Trauma Injury, Sepsis, Immunosuppression, Chronic Critical Illness
Interventions: Data Collection, Bone marrow collection and blood collection, Serial interviews to complete surveys and questionnaires, Telephone follow up call; Other · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 100 Years
Enrollment: 255 participants
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Sepsis
Interventions: IVIG, Placebo; Drug
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 72 Hours
Enrollment: 2,416 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1988 – 1991
U.S. locations: 8
States / cities: Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 5 more

Conditions: Infection, Hospital
Interventions: Passive disinfection device; Device
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Maplewood, Minnesota

Conditions: Sepsis-Induced Hypotension
Interventions: REGN7544, PB; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 16
States / cities: Tucson, Arizona • New Haven, Connecticut • Atlanta, Georgia + 10 more

Conditions: Sepsis, Venous Thromboembolism, Disseminated Intravascular Coagulation
Interventions: Diagnosis of both VTE and sepsis; Other
Lead sponsor: Bayer; Industry
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Whippany, New Jersey

Search by objective public record fields.

Impact of a Prehospital Sepsis Protocol on Timely Antibiotic Administration and Subsequent Adverse Events

Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol

Safe and Explainable AI

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis

EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 1)

VENOUS: A Translational Study of Enterococcal Bacteremia

Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients

New Strategy to Predict Early Sepsis

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

A Pilot Randomized Controlled Trial for Antibiotic Exposure in Neonatal Sepsis Using Neutrophil CD64

EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock

Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Mupirocin-Iodophor ICU Decolonization Swap Out Trial

Project 4B: Lower Extremity Strength Training in ICU Patients

Dialysis Catheter Caps Case Feasibility Study

Plastic Hat Trial to Prevent Hypothermia in Preterm Newborns in the Delivery Room

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty

NICU Antibiotics and Outcomes Trial

Pathological Myeloid Activation After Sepsis and Trauma

Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection

Passive Disinfection Cap Compliance Study

A Study of REGN7544 for the Treatment in Adult Patients With Sepsis-Induced Hypotension

An Observational Study in the United States to Learn How Venous Thromboembolism, Disseminated Intravascular Coagulation, and Sepsis Are Related