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ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:42 PM EDT

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Showing 1–24 of 311 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Huntington's Disease
Interventions
intra-striatal rAAV5-miHTT, Imitation (sham) surgery
Genetic · Other
Lead sponsor
UniQure Biopharma B.V.
Industry
Eligibility
25 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
12
States / cities
Birmingham, Alabama • Tucson, Arizona • San Francisco, California + 9 more
Conditions
Macular Telangiectasia Type 2 (MacTel)
Interventions
NT-501/revakinagene taroretcel-lwey
Combination Product
Lead sponsor
Neurotech Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
23
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 19 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acupuncture for Post-Operative Pain Control for Patients Undergoing Gynecological Surgery

NCT02855567
Conditions
Post-operative Pain, Gynecological Surgery, Acupuncture
Interventions
Acupuncture needles
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Not listed Phase 4 Interventional Accepts healthy volunteers

Perioperative Mirror Therapy and Phantom Limb Pain

NCT02383979
Conditions
Phantom Limb Pain, Phantom Pain, Phantom Sensation, Pseudomelia
Interventions
Sham (Comparator) Plasma Ball, Mirror
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 30 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
San Diego, California
Conditions
Surgery
Interventions
Auricular Acupuncture, Sham Acupuncture
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Quality-of-Life Improvements Using UroShield Device

NCT06319352
Conditions
Quality of Life, Catheter-Associated Urinary Tract Infection
Interventions
Active UroShield, Sham UroShield
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Saline, Michigan
Conditions
Venous Stasis Ulcers
Interventions
PEMF therapy with a high-power PEMF device, PEMF therapy with a medium PEMF power device, PEMF therapy with a low-power PEMF device, PEMF therapy with the sham PEMF device
Device
Lead sponsor
PEMF Systems, Inc.
Industry
Eligibility
21 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)

NCT01391832
Conditions
Post Traumatic Stress Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Processing Therapy, Repetitive Transcranial Magnet Stimulation (rTMS)
Device · Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 60 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
Interventions
ACTIVE cryoneurolysis, SHAM cryoneurolysis
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
La Jolla, California
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Healing Touch on Post Operative Pediatric Patients

NCT01738308
Conditions
Surgery, Stress, Pain, Children, Post-Traumatic Stress Disorder
Interventions
Healing Touch, Healing Touch Sham Treatment
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 4 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Parkinson Disease
Interventions
embryonic dopamine cell implant surgery, placebo
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2009
U.S. locations
3
States / cities
Denver, Colorado • Manhasset, New York • New York, New York
Conditions
Episodic Memory
Interventions
Brain stimulation
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Pain, Postoperative, Opioid Use, Lumbar Spine Injury
Interventions
Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN), Sham Control Device
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Otitis Media With Effusion
Interventions
OTO-201, Sham
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low-level Laser and Lifestyle Modifications

NCT05083442
Conditions
Overweight and Obesity, Weight Loss
Interventions
Low Level Laser Therapy, Sham (placebo)
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Advanced Malignant Neoplasm
Interventions
Cordotomy, Morphine, Questionnaire Administration, Sham Intervention
Procedure · Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Conditions
Chronic Back Pain, Chronic Pain (Back / Neck)
Interventions
low intensity focused ultrasound (LIFU)
Device
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Obsessive-Compulsive Disorder
Interventions
ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Palo Alto, California • Boston, Massachusetts
Conditions
Cardiac Surgery
Interventions
Remote Ischemic Preconditioning, Sham
Procedure
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Portland, Maine • Winston-Salem, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Focused Ultrasound for the Complex Patient

NCT06453109
Conditions
Opioid Use Disorder, Chronic Back Pain, Anxiety
Interventions
low intensity focused ultrasound (LIFU)
Device
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed No phase listed Observational

Bronchial Thermoplasty 10+ Year Study

NCT03243292
Conditions
Asthma
Interventions
Bronchial Thermoplasty
Other
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
6
States / cities
Los Angeles, California • Detroit, Michigan • Saint Paul, Minnesota + 3 more
Completed Not applicable Interventional Results available

Auricular Neuromodulation for FESS

NCT06662422
Conditions
Functional Endoscopic Sinus Surgery, Vagal Nerve Stimulation, Platelet Activation
Interventions
Spark Biomedical Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN) System
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Chronic Sinusitis, Nasal Polyposis
Interventions
S8 Sinus Implant, Mometasone furoate nasal spray, Sham
Drug · Procedure
Lead sponsor
Intersect ENT
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
40
States / cities
Birmingham, Alabama • Irvine, California • Sacramento, California + 33 more
Conditions
Post Operative Delirium, Cognitive Impairment, Vagus Nerve Stimulation, Depression
Interventions
Transcutaneous vagal nerve stimulation, Sham (No Treatment)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois