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ClinicalTrials.gov public records Last synced Nov 1, 2026, 4:56 AM EST

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Showing 1513–1536 of 2,491 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal Clear all
Completed Not applicable Interventional

Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Cervicogenic Headache

NCT02373605
View directory record Official record
Conditions
Cervicogenic Headaches
Interventions
Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Nov 1, 2026, 4:56 AM EST
Completed Early Phase 1 Interventional

Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCI

NCT02370862
View directory record Official record
Conditions
Spinal Cord Injury, Neurogenic Bowel
Interventions
Neostigmine and Glycopyrrolate
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Terminated Not applicable Interventional Results available

Effects of Combined Spinal Direct Current Stimulation on Upper Limb Recovery in Acquired Brain Injury

NCT03100370
View directory record Official record
Conditions
Acquired Brain Injury
Interventions
tsDCS-Anodal Stimulation, tsDCS-Cathodal Stimulation, tsDCS-Sham Stimulation, Robotic-assisted training of arm and hand functions
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Nov 1, 2026, 4:56 AM EST
Recruiting No phase listed Observational Accepts healthy volunteers

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

NCT06034405
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Cardiac Amyloidosis, ATTR Amyloidosis Wild Type, ATTR Gene Mutation, ATTRV122I Amyloidosis, Cardiomyopathy, Hypertrophic
Interventions
Tc99-PYP or Tc99-HDMP Scan
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
50 Years and older
Enrollment
1,663 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
6
States / cities
Beverly Hills, California • Boston, Massachusetts • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Recruiting Phase 1 Interventional

A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury

NCT06841770
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injury, Acute, Spinal Cord Injury, Spinal Cord Injury, Chronic
Interventions
OPC1
Biological
Lead sponsor
Lineage Cell Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2037
U.S. locations
2
States / cities
Downey, California • La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Recruiting Phase 3 Interventional

Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery

NCT07539623
View directory record Official record
Conditions
Bariatric Surgery, Cardiac Surgery With Sternotomy, Post-operative Pain
Interventions
Suzetrigine, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 85 Years
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Completed No phase listed Observational

DuraSeal Exact Spine Sealant System Post-Approval Study

NCT01410864
View directory record Official record
Conditions
Dural Sealing
Interventions
DuraSeal Exact Spine Sealant System, Control
Device · Other
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older
Enrollment
924 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
36
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 31 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Nov 1, 2026, 4:56 AM EST
Completed Phase 1Phase 2 Interventional

Cervicogenic Headache Dose-Response

NCT01530321
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Spinal Manipulation, Light Massage
Other
Lead sponsor
University of Western States
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bloomington, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Nov 1, 2026, 4:56 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Dietary Patterns and Cardiovascular (CVD) Risk in Spinal Cord Injury (SCI) Factors In Individuals With Chronic Spinal Cord Injury

NCT01025609
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
38 Years to 55 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Nov 1, 2026, 4:56 AM EST
Completed Not applicable Interventional Results available

Safety and Effectiveness Study of the Precision SCS Systems Adapted for High-Rate Spinal Cord Stimulation

NCT02093793
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
PRECISION SCS Adapted for High-Rate SCS
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
20
States / cities
Phoenix, Arizona • Carlsbad, California • La Jolla, California + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Nov 1, 2026, 4:56 AM EST
Active, not recruiting No phase listed Observational Accepts healthy volunteers

A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals with Friedreich Ataxia (TRACK-FA)

NCT04349514
View directory record Official record
Conditions
Friedreich Ataxia
Interventions
Natural history
Other
Lead sponsor
Monash University
Other
Eligibility
5 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
Gainesville, Florida • Minneapolis, Minnesota • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Nov 1, 2026, 4:56 AM EST
Completed Not applicable Interventional

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

NCT05432999
View directory record Official record
Conditions
Spinal Cord Injuries, Spasticity, Muscle, Spastic Paraplegia, Spastic Quadriplegia, Spastic Tetraplegia, Paraplegia, Tetraplegia
Interventions
Extracorporeal Shockwave Therapy
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury

NCT02115685
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Treadmill Training
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Nov 1, 2026, 4:56 AM EST
Completed No phase listed Observational Accepts healthy volunteers Results available

Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development

NCT01736553
View directory record Official record
Conditions
Spinal Muscular Atrophy (SMA)
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
Up to 6 Months
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
15
States / cities
Davis, California • Los Angeles, California • Aurora, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Nov 1, 2026, 4:56 AM EST
Completed Not applicable Interventional

Measurement of Hemodynamic Variables Under Spinal Anesthesia With Varied Positioning

NCT02883075
View directory record Official record
Conditions
Pregnancy, Anesthesia
Interventions
Supine position, Right lateral position, Left lateral position
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2019 · Synced Nov 1, 2026, 4:56 AM EST
Completed Not applicable Interventional

Incidence of Proximal Junctional Kyphosis (PJK) in Long Posterior Spinal Fusion: A Study Comparing Traditional Open Surgery to Minimally Invasive Percutaneous Technique at the Proximal Fusion Levels

NCT00890227
View directory record Official record
Conditions
Scoliosis, Kyphosis
Interventions
Traditional technique, Minimally invasive technique
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Nov 1, 2026, 4:56 AM EST
Completed Not applicable Interventional

A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections

NCT01053273
View directory record Official record
Conditions
Low Back Pain
Interventions
Caudal Epidural Injection, percutaneous adhesiolysis
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Nov 1, 2026, 4:56 AM EST
Enrolling by invitation Not applicable Interventional

Effect of Blood Flow-restricted Exercise Frequency on Strength Recovery Following Incomplete SCI

NCT07678437
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Blood flow-restricted exercise
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Completed No phase listed Observational

Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery

NCT00984672
View directory record Official record
Conditions
Lumbar Degenerative Disease
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2022 · Synced Nov 1, 2026, 4:56 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery

NCT06570577
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Inter-semispinalis Plane Block, Opioids
Procedure · Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Recruiting No phase listed Observational

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

NCT04174157
View directory record Official record
Conditions
Spinal Muscular Atrophy (SMA)
Interventions
Prospective observational registry, Zolgensma
Other · Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2038
U.S. locations
50
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Loma Linda, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Nov 1, 2026, 4:56 AM EST
Completed No phase listed Observational

Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

NCT03539770
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent
Interventions
Posterior spinal fusion
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years to 21 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Nov 1, 2026, 4:56 AM EST
Recruiting Not applicable Interventional

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

NCT04142177
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Pain EASE, Tailored exercise, Continued Care and Active Monitoring, Cognitive Behavioral Therapy (CBT), Spinal Manipulation Therapy (SMT), Yoga
Other · Procedure · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
2,529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
19
States / cities
Phoenix, Arizona • Loma Linda, California • Long Beach, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Nov 1, 2026, 4:56 AM EST
Terminated Not applicable Interventional

Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity

NCT04742257
View directory record Official record
Conditions
Muscle Spasticity, Stroke
Interventions
MyoRegulator® device
Device
Lead sponsor
PathMaker Neurosystems Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cambridge, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Nov 1, 2026, 4:56 AM EST