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ClinicalTrials.gov public records Last synced Nov 10, 2026, 5:11 PM EST

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Showing 169–192 of 549 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Surgical Approach Clear all

Conditions: Degenerative Disc Disease
Interventions: XL TDR, Lumbar fusion surgery; Device · Other
Lead sponsor: NuVasive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 246 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 17
States / cities: Campbell, California • Thousand Oaks, California • Durango, Colorado + 14 more

Conditions: Hand Injury, Wrist Injury, Finger Injury
Interventions: 0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.; Procedure
Lead sponsor: Jose Soberon, MD; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Kidney Transplant Failure and Rejection
Interventions: Tacrolimus (TAC), Sirolimus, Alemtuzumab, Mycophenolate mofetil (MMF); Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Vestibular Schwannoma, Acoustic Neuroma, Sensorineural Hearing Loss, Asymmetric Sensorineural Hearing Loss, Cochlear Nerve Damage, Cochlear Nerve Deafness, Skull Base Neoplasms, Auditory; Nerve
Interventions: Auditory Nerve Test System; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 12 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Degenerative Disc Disease
Interventions: CALIBER; Device
Lead sponsor: Globus Medical Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Miami Beach, Florida • Charlotte, North Carolina

Conditions: Cervical Degenerative Disc Disease
Interventions: Anterior Cervical Discectomy and Fusion; Device
Lead sponsor: Synergy Spine Solutions; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 23
States / cities: Scottsdale, Arizona • Beverly Hills, California • Los Angeles, California + 20 more

Conditions: Metastatic Breast Cancer, HER2-positive Breast Cancer
Interventions: Lumpectomy or mastectomy, Radiotherapy, Trastuzumab, Pertuzumab, Paclitaxel, or a combination of these drugs; Procedure · Radiation · Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Bariatric Surgery
Interventions: Positive Psychology-Motivational Interviewing, Physical Activity Education Control; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ankle Fractures, Distal Radius Fracture
Interventions: Peripheral Nerve Block; Procedure
Lead sponsor: MaineGeneral Health; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Augusta, Maine

Conditions: S. Aureus Transmission, Surgical Site Infection
Interventions: OR PathTrac Feedback Optimization; Other
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Enrollment: 804 participants
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Georgetown, District of Columbia

Conditions: Breast Cancer Female, Early-stage Breast Cancer
Interventions: Lumpectomy, Intraoperative Radiation Therapy; Procedure · Radiation
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 55 Years and older · Female only
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2033
U.S. locations: 1
States / cities: Macon, Georgia

Conditions: Langerhans Cell Histiocytosis
Interventions: Prednisone, Vinblastine, mercaptopurine, INDOMETHACIN, Methotrexate, Cytosine Arabinoside, 2-chlorodeoxyadenosine, hematopoietic stem cell transplantation (RIC-HSCT), Intravenous immunoglobulin; Drug · Procedure · Biological
Lead sponsor: North American Consortium for Histiocytosis; Other
Eligibility: Up to 18 Years
Enrollment: 1,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2031
U.S. locations: 42
States / cities: Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 36 more

Conditions: Cataract
Interventions: TriMoxiVanc, Moxifloxacin HCl 0.5%, Ilevro, Prednisolone acetate 1%; Drug
Lead sponsor: Carolina Eyecare Physicians, LLC; Other
Eligibility: 50 Years to 80 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 4
States / cities: Bloomington, Minnesota • Stillwater, Minnesota • Garden City, New York + 1 more

Conditions: Overactive Bladder, Urinary Incontinence
Interventions: Botox; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Degenerative Disc Disease, Spondylolisthesis, Lumbar Disc Herniation
Interventions: Oblique Lateral Lumbar Fusion; Procedure
Lead sponsor: Tristate Brain and Spine Institute; Other
Eligibility: Not listed
Enrollment: 303 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2025
U.S. locations: 1
States / cities: Alexandria, Minnesota

Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: Single-Level Posterior Decompression, DIAM Spinal Stabilization, Fusion; Procedure · Device
Lead sponsor: Medtronic Spinal and Biologics; Industry
Eligibility: 35 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 9
States / cities: Fremont, California • Jacksonville, Florida • Melbourne, Florida + 6 more

Conditions: Post-surgical Pain
Interventions: In-person cognitive behavioral therapy, Virtual reality-delivered cognitive behavioral therapy; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Athletic Injuries, Sport Injuries
Interventions: Community Resiliency Model (CRM), Control; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 26 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency
Interventions: Blood Draw; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years and older
Enrollment: 378 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2020
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Lung Diseases
Interventions: lung resection with Lung Resection Marker Locator Kit; Device
Lead sponsor: Navigation Sciences, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ventral Hernia, Adhesions
Interventions: Clinically-Indicated Abdominal Re-Exploration Surgery; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 173 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 6
States / cities: Phoenix, Arizona • San Diego, California • Springfield, Massachusetts + 3 more

Conditions: Osteoarthritis of the Hip
Interventions: Anterior Approach / Posterior Approach, Anterior versus Posterior Approach for total hip replacement; Procedure
Lead sponsor: Barrett, William, M.D.; Individual
Eligibility: 20 Years to 75 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Renton, Washington

Conditions: Periodontal Diseases
Interventions: Microsurgical approach with Digital Microscope; Procedure
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 18 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Dental Implants, Ceramic Implant
Interventions: Immediate dental implants placements on fresh sockets after tooth extraction; Procedure
Lead sponsor: Swiss Dental Solutions; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Englewood Cliffs, New Jersey

Search by objective public record fields.

XL TDR® eXtreme Lateral Total Disc Replacement for the Treatment of Lumbar Degenerative Disc Disease (DDD)

Comparing Two Injection Sites of Local Anesthetic for Hand Surgery

A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression

Auditory Nerve Test System During Vestibular Schwannoma Resection

Study of an Expandable Interbody Device for the Lumbar Spine

The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery

A Study of Surgery and Radiotherapy in People With Breast Cancer

Gaining Optimism After Weight Loss Surgery (GOALS) II

Nerve Block for Pain Control After Fracture Surgery

Reducing Perioperative S. Aureus Transmission Via OR PathTrac

IORT-Breast at Medical Center Navicent Health

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

Dropless vs. Standard Drops Contralateral Eye Study

Botulinum-A Toxin Injection for Detrusor Hyperreflexia in Spinal Cord Injury: A Non-Surgical Approach.

Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion

DIAM™ Spinal Stabilization System vs. Decompression, Formerly vs. Posterolateral Fusion

Opioid Sparing Cognitive Behavioral Therapy (CBT) Intervention to Manage Acute Pain, and Pain Catastrophizing in Surgical Patients

Rise With Resilience

Biomarkers in Aortic Stenosis - B.A.S.S.

Image - Navigated Resection of Lung Nodules

Comparative Effectiveness Multicenter Trial for Adhesion Characteristics of Ventral Hernia Repair Mesh

Total Hip Arthroplasty (THA) Surgical Techniques Comparing the Direct Anterior Approach to the Posterior Approach

Microsurgery and Periodontal Healing

Zirconia Implants: Practice-based Evidence