- Conditions
- Pulmonary Infections, Pseudomonas Aeruginosa in Cystic Fibrosis
- Interventions
- TBM100
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 157 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 20
- States / cities
- Little Rock, Arkansas • Denver, Colorado • Jacksonville, Florida + 16 more
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Showing 1–19
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- Conditions
- Cystic Fibrosis
- Interventions
- Tobramycin Inhalation Powder
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 21
- States / cities
- Mobile, Alabama • Los Angeles, California • Sacramento, California + 18 more
- Conditions
- Bronchopulmonary Dysplasia
- Interventions
- Tobramycin solution for inhalation 78mg dose, Tobramycin solution for inhalation 150mg dose, Tobramycin solution for inhalation 216mg dose, Tobramycin solution for inhalation 300mg dose
- Drug
- Lead sponsor
- Erik Allen Jensen
- Other
- Eligibility
- 4 Weeks and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Cystic Fibrosis
- Interventions
- AZLI, Placebo to match AZLI, Tobramycin inhalation solution
- Drug
- Lead sponsor
- Gilead Sciences
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 107 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 71
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 62 more
- Conditions
- Cystic Fibrosis
- Interventions
- TOBIpodhaler
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Pseudomonas Aeruginosa in Cystic Fibrosis
- Interventions
- TOBI® PODHALER®, TOBI®, Bethkis®, Cayston®
- Drug
- Lead sponsor
- Mylan Inc.
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 409 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 47
- States / cities
- Anchorage, Alaska • Little Rock, Arkansas • Bellflower, California + 43 more
- Conditions
- Cystic Fibrosis
- Interventions
- Tobramycin for Inhalation
- Drug
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 6 Months to 5 Years
- Enrollment
- 98 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2002
- U.S. locations
- 9
- States / cities
- Palo Alto, California • Denver, Colorado • Baltimore, Maryland + 6 more
- Conditions
- Cystic Fibrosis
- Interventions
- Tobramycin Inhalation Powder, Tobramycin Solution for Inhalation
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 517 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 24
- States / cities
- Hartford, Connecticut • Atlanta, Georgia • Chicago, Illinois + 21 more
- Conditions
- Cystic Fibrosis
- Interventions
- azithromycin, placebo, Tobramycin solution for inhalation
- Drug
- Lead sponsor
- Bonnie Ramsey
- Other
- Eligibility
- 6 Months to 18 Years
- Enrollment
- 221 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 45
- States / cities
- Anchorage, Alaska • Tucson, Arizona • Little Rock, Arkansas + 40 more
- Conditions
- Cystic Fibrosis
- Interventions
- MP-376 (Levofloxacin Solution for Inhalation), TIS (Tobramycin Inhalation Solution)
- Drug
- Lead sponsor
- Amgen
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 282 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 99
- States / cities
- Mobile, Alabama • Anchorage, Alaska • Phoenix, Arizona + 86 more
- Conditions
- Cystic Fibrosis, Pulmonary Disease, Chronic Obstructive
- Interventions
- Tobramycin solution for inhalation (TOBI), Oral placebo, Oral ciprofloxacin
- Drug
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 1 Year to 12 Years
- Enrollment
- 304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2009
- U.S. locations
- 54
- States / cities
- Birmingham, Alabama • Los Angeles, California • Oakland, California + 49 more
- Conditions
- Cystic Fibrosis
- Interventions
- Placebo, Tobi Podhaler
- Drug · Device
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 13
- States / cities
- Phoenix, Arizona • Long Beach, California • Los Angeles, California + 9 more
- Conditions
- Chronic Sinusitis
- Interventions
- SPRC-AB01
- Drug
- Lead sponsor
- Naryx Pharma
- Industry
- Eligibility
- 16 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 43
- States / cities
- Hoover, Alabama • Jonesboro, Arkansas • Fresno, California + 40 more
- Conditions
- Cystic Fibrosis
- Interventions
- Placebo, Tobi Podhaler
- Drug · Device
- Lead sponsor
- Mylan Inc.
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 9
- States / cities
- Miami, Florida • Orlando, Florida • Pensacola, Florida + 4 more
- Conditions
- Cystic Fibrosis
- Interventions
- azithromycin, placebo (for azithromycin), inhaled tobramycin
- Drug
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 119 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 39
- States / cities
- Los Angeles, California • Palo Alto, California • San Diego, California + 33 more
- Conditions
- Cystic Fibrosis
- Interventions
- TOBI™ Podhaler™ 112 mg inhaled twice daily, Colistimethate 75 mg inhaled two times daily
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 12 Years to 75 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Cystic Fibrosis
- Interventions
- Aztreonam for Inhalation Solution (AZLI), Tobramycin Inhalation Solution (TIS)
- Drug
- Lead sponsor
- Gilead Sciences
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 29
- States / cities
- Anchorage, Alaska • Phoenix, Arizona • Tuscon, Arizona + 25 more
- Conditions
- Cystic Fibrosis
- Interventions
- FTI, AZLI, Placebo, AZLI
- Drug
- Lead sponsor
- Gilead Sciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 36
- States / cities
- Anchorage, Alaska • Phoenix, Arizona • Tucson, Arizona + 32 more
- Conditions
- Cystic Fibrosis
- Interventions
- Amiloride Solution for Inhalation
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 6 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts