Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 8, 2026, 11:28 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 653 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Total Cholesterol Clear all

Conditions: Hypertension
Interventions: CHW Intervention, Wait List Control Group; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 85 Years
Enrollment: 305 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Hypercholesterolemia
Interventions: Gamma Delta Tocotrienols - Low Dose, Gamma Delta Tocotrienols - High Dose, Sugar Pill; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 35 Years to 70 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cardiovascular Diseases, Heart Diseases
Interventions: Family Passport to Heart Health Program, General Educational Materials; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 20 Years to 79 Years
Enrollment: 501 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: New York, New York

Conditions: Hyperlipidemia
Interventions: Plant sterol, Placebo; Dietary Supplement
Lead sponsor: University of Manitoba; Other
Eligibility: 30 Years to 75 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Beltsville, Maryland

Conditions: Smith-Lemli-Opitz Syndrome
Interventions: crystalline cholesterol oil-based suspension; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Not listed
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiovascular Risk, LDL-C, Lipids, Digital Health, Implementation Science
Interventions: Corrie Lipids Digital Health Program; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Dyslipidemia
Interventions: Atorvastatin, ABT335, ER Niacin; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Autism, Asperger Disorder, PDD-NOS
Interventions: Cholesterol; Other
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 4 Years to 12 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Type 2 Diabetes
Interventions: Plant-based diet with no oxysterols, Standard ADA Diet (SADA); Behavioral
Lead sponsor: Morehouse School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Interventions: IMNN-001, Carboplatin, Paclitaxel; Biological · Drug
Lead sponsor: Imunon; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 20
States / cities: Birmingham, Alabama • Mobile, Alabama • Newport Beach, California + 17 more

Conditions: Metabolic Syndrome
Interventions: Pioglitazone, Placebo, Niacin ER, Aspirin; Drug · Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Coronary Heart Disease
Interventions: gemfibrozil, Placebo; Drug · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Up to 73 Years · Male only
Enrollment: 2,531 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1991 – 1999
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Diabetes, Metabolic Syndrome
Interventions: Cardiac CT, Usual medical care; Diagnostic Test · Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 90 Years
Enrollment: 193 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2016
U.S. locations: 1
States / cities: Orange, California

Conditions: Familial Hypercholesterolemia
Interventions: Cascade Screening; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cardiovascular Disease, Cardiomyopathy, Heart Disease, Myocardial Disease, Myocardial Ischemia
Interventions: Atorvastatin Calcium; Drug
Lead sponsor: Philip Binkley; Other
Eligibility: 18 Years to 85 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Alzheimer's Disease
Interventions: MRI, MR Spectroscopy, MR Perfusion; Device
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 45 Years to 65 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hyperlipemia, Mixed, ASCVD
Interventions: Alert; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hyperlipidemia
Interventions: Evolocumab, Ezetimibe, Placebo to Evolocumab, Placebo to Ezetimibe; Biological · Drug · Other
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 615 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 47
States / cities: Birmingham, Alabama • Chandler, Arizona • Little Rock, Arkansas + 40 more

Conditions: Healthy Volunteers
Interventions: Cardiosyn; Dietary Supplement
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 99 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cardiovascular Diseases, Lipid Testing, Primary Prevention of Cardiovascular Disease
Interventions: Mailed patient outreach intervention; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 35 Years to 75 Years
Enrollment: 480 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 3
States / cities: Flagstaff, Arizona • Chicago, Illinois

Conditions: Healthy Participants
Interventions: AZD0780, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Brooklyn, Maryland

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: Winthrop University Hospital; Other
Eligibility: 40 Years to 70 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Coronary Artery Disease, Carotid Artery Diseases, Atherosclerosis
Interventions: Atorvastatin, Niacin, Colesevelam, Placebo Niacin, Placebo Colesevelam; Drug
Lead sponsor: University of Washington; Other
Eligibility: 21 Years to 70 Years
Enrollment: 217 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2019
U.S. locations: 4
States / cities: Los Angeles, California • Boise, Idaho • Seattle, Washington + 1 more

Conditions: Cholesterol
Interventions: Standard whey, Hydrolyzed whey; Dietary Supplement
Lead sponsor: Medinutra LLC; Other
Eligibility: 21 Years to 59 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Dublin, Ohio

Search by objective public record fields.

Project IMPACT: CHW Intervention

Effects of a Supplement Derived From Palm Oil on Cholesterol Levels in the Blood

Evaluating the Effectiveness of a Family Heart Health Educational Program (The FIT-Heart Study)

Genetic Basis for Heterogeneity in Response of Plasma Lipids to Plant Sterols

Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome

Impact of the Corrie Lipids Digital Health Program on Lipid Optimization

Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study

Cholesterol in ASD: Characterization and Treatment

Dietary Oxysterols and β-Cell Function Among African Americans

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)

Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL

The VA HDL Intervention Trial (HIT): Secondary Prevention of Coronary Heart Disease in Men With Low HDL-Cholesterol and Desirable LDL-Cholesterol

Cardiac CT's Role in Asymptomatic Patients With Diabetes and Metabolic Syndrome

Equitable Implementation of Cascade Screening for Familial Hypercholesterolemia

Statin Therapy for Ischemic and Nonischemic Cardiomyopathy

Statins in Cerebral Blood Flow and Neuronal Activity--A Pilot Study

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management

Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2

Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis

Promoting Cholesterol Screening

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels

Anti-inflammatory Agents and Cholesterol Metabolism

Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication

Whey Protein Comparisons for Blood Lipid Effects