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ClinicalTrials.gov public records Last synced Nov 7, 2026, 12:38 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2593–2616 of 3,107 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Cystic Fibrosis
Interventions: Yoga treatment program; Other
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 9 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Heart Failure
Interventions: Brief Cognitive Therapy Intervention; Behavioral
Lead sponsor: Rebecca L. Dekker, PhD, RN, APRN; Other
Eligibility: 21 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Depressive Disorder, Major, Anhedonia
Interventions: Aticaprant, Placebo; Drug · Other
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 39
States / cities: Huntsville, Alabama • Phoenix, Arizona • Tucson, Arizona + 33 more

Conditions: Androgenetic Alopecia, Androgenic Alopecia, Telogen Effluvium, Thinning Hair, Hair Loss/Baldness, Hair Thinning
Interventions: ALRV5XR, ALRV5XR Shampoo, ALRV5XR Conditioner, ALRV5XR Hair Follicle Serum (Nutriment), Placebo, Placebo Shampoo, Placebo Conditioner, Placebo Hair Follicle Serum (Nutriment); Dietary Supplement · Other
Lead sponsor: Arbor Life Labs; Industry
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Treatment Resistant Depression (TRD), Major Depressive Disorder (MDD)
Interventions: Spaced Transcranial Direct Current Stimulation (tDCS), Sham Spaced tDCS; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 70 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: San Diego, California

Conditions: Loneliness, Mental Health Issue, Distress, Emotional, Depression, Anxiety, Stress
Interventions: Overcoming Loneliness three-week intervention, Overcoming Loneliness single-session intervention, Single-session "Sharing Feelings" program, The Blu Surfer program: a popular online content-based intervention for psychological distress, The Action Brings Change (ABC) Program (TEAM Lab version), Online help-seeking as usual, The Lonely Blu Surfer program: a popular online content-based intervention for loneliness, Overcoming loneliness SSI 8-minute version; Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 16 Years and older
Enrollment: 4,370 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Irvine, California

Conditions: Sleepiness, Daytime
Interventions: LED bright light treatment device; Device
Lead sponsor: Mclean Hospital; Other
Eligibility: 13 Years to 18 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Bipolar Disorder, Alcohol Dependence
Interventions: Placebo, Quetiapine; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Sleep Initiation and Maintenance Disorders, Depression
Interventions: Eszopiclone, Fluoxetine, Placebo; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Major Depressive Disorder
Interventions: Intermittent Theta Burst Stimulation (iTBS), Transcranial Alternating Current Stimulation (tACS), Psychotherapy, Sham (Placebo) Transcranial Alternating Current Stimulation (tACS); Device · Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 70 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Eating Disorders (Excluding Anorexia Nervosa), Depression
Interventions: High Intensity Strategy: Train-the-trainer, Low Intensity Strategy: Expert Consultation; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 223 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression, Anxiety Disorders and Symptoms
Interventions: Amplification of Positivity Training (6 Sessions), Stress Management Training (6 Sessions); Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 55 Years
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Cancer of Head and Neck, Breast Cancer, Prostate Cancer, Nicotine Dependence
Interventions: Transcranial Magnetic Stimulation Clinical Research System; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Major Depressive Disorder, Major Depressive Episode
Interventions: Universal Screening Arm; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: Not listed
Enrollment: 12,909 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Major Depressive Disorder
Interventions: NeuroStar TMS; Device
Lead sponsor: Neuronetics; Other
Eligibility: 18 Years to 70 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 6
States / cities: Chicago, Illinois • Baltimore, Maryland • Lincoln, Nebraska + 3 more

Conditions: Major Depressive Disorder
Interventions: saredutant (SR48968), escitalopram, placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 643 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Depression
Interventions: Behavioral Activation; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 12 Years to 18 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Parents
Interventions: CBT; Behavioral
Lead sponsor: University of Missouri, Kansas City; Other
Eligibility: 18 Months to 17 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Major Depressive Disorder, Bipolar Disorder
Interventions: Mindfulness-based cognitive therapy; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Female only
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Los Angeles, California • Boulder, Colorado

Conditions: Back Pain, Depression
Interventions: Cognitive behavioral therapy, Antidepressants, Problem solving therapy; Behavioral · Drug
Lead sponsor: Kaiser Permanente; Other
Eligibility: 25 Years to 74 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression
Interventions: S-citalopram, Cognitive behavioral therapy (CBT), TRODAT-1 single photon emission computed tomographic (SPECT) imaging; Drug · Behavioral · Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Major Depressive Disorder With Mixed Features
Interventions: Lurasidone, Placebo; Drug
Lead sponsor: Sumitomo Pharma America, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 19
States / cities: Birmingham, Alabama • Escondido, California • Garden Grove, California + 15 more

Conditions: Infant, Newborn, Hypoxia-Ischemia, Brain
Interventions: Induced hypothermia, Control; Device
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Up to 6 Hours
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2010
U.S. locations: 16
States / cities: Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more

Conditions: Major Depressive Disorder (MDD)
Interventions: Radafaxine; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 546 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 29
States / cities: Little Rock, Arkansas • Newport Beach, California • Farmington, Connecticut + 25 more

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Treatment of Anxiety/Depression and Pain Through Relaxation Yoga for Patient With Cystic Fibrosis (CF)

Helping Others Toward Positive Emotions in People With Heart Failure

A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss

Home-Based Randomized Trial of Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression

SSIs for Mental Health and Loneliness

Effects of Litebook EDGE™ Phototherapy on Academic Performance and Brain Activity

Quetiapine for Bipolar Disorder and Alcohol Dependence

Improving Sleep and Psychological Functioning in People With Depression and Insomnia

CARED : A Novel Rapid Treatment Paradigm for Depression

Implementation of Evidence-based Treatments for On-campus Eating Disorders

Amplification of Positivity to Enhance Social Connections in Anxiety and Depression

Brain Stimulation For Cancer Smokers

Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder

Maintenance NeuroStar Transcranial Magnetic Stimulation (TMS) in Patients With Major Depressive Disorder

An Eight-week Study of Saredutant and Escitalopram as Combination Treatment for Major Depressive Disorder

Activating and Connecting Teens (ACT) Study

Group CBT in Parents of Children With Food Allergy

Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders

Combined Interventions for Treating Depression and Chronic Back Pain

Effects of Antidepressant Therapy on Brain Dopamine Transporter Activity in People With Major Depression

Major Depressive Disorder (MDD) With Mixed Features - Flexible Dose

Whole-Body Cooling for Birth Asphyxia in Term Infants

An 8 Week Depression Study In Adults Diagnosed With Major Depressive Disorder