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ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:01 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 673–696 of 2,819 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: matched control group Clear all

Conditions: Valve Disease, Aortic, Mitral Regurgitation (MR), Aortic Stenosis, Valvular Heart Disease, Tricuspid Regurgitation (TR), Aortic Regurgitation
Interventions: Not listed
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Dizziness, Brain Injury
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Mountain Home, Tennessee

Conditions: Systemic Sclerosis-associated Interstitial Lung Disease
Interventions: Abituzumab 1500 mg, Abituzumab 500 mg, Placebo; Drug
Lead sponsor: EMD Serono Research & Development Institute, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 18
States / cities: Los Angeles, California • Farmington, Connecticut • Washington D.C., District of Columbia + 12 more

Conditions: Reading Disability
Interventions: GraphoLearn reading intervention, Math control intervention; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 6 Years to 11 Years
Enrollment: 315 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Self Harm, Suicidal Ideation
Interventions: tVNS Program, Phone App Program, tVNS and Phone App Program, Sham tNVS and Control App; Device · Other · Combination Product
Lead sponsor: University of Notre Dame; Other
Eligibility: 13 Years to 17 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: South Bend, Indiana • Rochester, New York

Conditions: Healthy Adults
Interventions: Body-Brain Trainer, Body Trainer, Brain Trainer, Expectancy Matched Control; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 55 Years to 80 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Multiple Sclerosis, Relapse
Interventions: Blood samples and processing; Diagnostic Test
Lead sponsor: Regina Elena Cancer Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Healthy Adult Volunteers
Interventions: BMS-986090, Placebo matching with BMS-986090, Keyhole limpet hemocyanin; Drug
Lead sponsor: Bristol-Myers Squibb; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Glendale, California • Baltimore, Maryland

Conditions: Physical Activity
Interventions: HIPP, Wellness contact control; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 50 Years to 69 Years · Female only
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Depressive Disorder
Interventions: Carbidopa/levodopa, Placebo, Exercise training, Control; Drug · Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 60 Years to 100 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Delirium, Alzheimer Disease
Interventions: Physical Exercise Intervention, Cognitive Training Intervention, Stretching Control, Cognitive Control; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 50 Years and older
Enrollment: 249 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 6
States / cities: Avon, Indiana • Carmel, Indiana • Fishers, Indiana + 1 more

Conditions: Supranuclear Palsy, Progressive
Interventions: BIIB092, Placebo; Drug
Lead sponsor: Biogen; Industry
Eligibility: 41 Years to 86 Years
Enrollment: 490 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 33
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Sun City, Arizona + 25 more

Conditions: Schizophrenia
Interventions: GSK239512, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 15
States / cities: Garden Grove, California • Los Angeles, California • National City, California + 11 more

Conditions: Diabetes Mellitus, Type 2
Interventions: Placebo, Linagliptin 5mg; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 15
States / cities: Birmingham, Alabama • Long Beach, California • North Hollywood, California + 12 more

Conditions: Metastatic Colorectal Cancer
Interventions: Regorafenib (Stivarga, BAY73-4506), Placebo, Best Supportive Care (BSC); Drug · Other
Lead sponsor: Bayer; Industry
Eligibility: 18 Years and older
Enrollment: 760 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 26
States / cities: Beverly Hills, California • Los Angeles, California • Mission Hills, California + 22 more

Conditions: Osteoarthritis, Knee
Interventions: Fisetin, Losartan, Placebo - Losartan, Placebo Fisetin; Drug
Lead sponsor: Steadman Philippon Research Institute; Other
Eligibility: 40 Years to 85 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Vail, Colorado

Conditions: Pulmonary Hypertension Associated With HFpEF
Interventions: TNX-103, Placebo; Drug
Lead sponsor: Tenax Therapeutics, Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 540 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 45
States / cities: Alexander City, Alabama • Tucson, Arizona • Sacramento, California + 40 more

Conditions: Mitochondrial Diseases, Maternally Inherited Diabetes and Deafness (MIDD), Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS), Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
Interventions: Sonlicromanol, Placebo; Drug
Lead sponsor: Khondrion BV; Industry
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Boston, Massachusetts • Cleveland, Ohio • Houston, Texas

Conditions: Major Depression, Post-Traumatic Stress Disorder
Interventions: Depression Care Quality Improvement Implementation; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Not listed
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 6
States / cities: Long Beach, California • Shreveport, Louisiana • Minneapolis, Minnesota + 3 more

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Tirasemtiv, Placebo tablets; Drug
Lead sponsor: Cytokinetics; Industry
Eligibility: 18 Years and older
Enrollment: 744 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 49
States / cities: Phoenix, Arizona • La Jolla, California • Los Angeles, California + 42 more

Conditions: Chronic Ankle Instability
Interventions: Real-world vibration feedback gait retraining; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Organ Transplant
Interventions: Mindfulness-Based Stress Reduction (MSBR), Health Education (HE), Delayed Intervention; Behavioral
Lead sponsor: National Institute of Nursing Research (NINR); NIH
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: COPD, Chronic Obstructive Pulmonary Disease, Moderate to Very Severe COPD
Interventions: Aclidinium Bromide, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 40 Years to 130 Years
Enrollment: 3,635 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 433
States / cities: Birmingham, Alabama • Florence, Alabama • Foley, Alabama + 334 more

Conditions: Cancer
Interventions: Goal-Focused Emotion-Regulation Therapy (GET), Individual Supportive Listening (ISL); Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 39 Years · Male only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Irvine, California

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DELINEATE-Prospective

Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)

Abituzumab in SSc-ILD

Neurocognitive Factors in EdTech Intervention Response

Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents

Characterizing the Synergistic Effects of Physical and Cognitive Training on Attention and Working Memory

Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis

Study to Evaluate the Safety, Tolerability, PK, and PD of BMS-986090 in Healthy Subjects

Home-based, Individually-tailored Physical Activity Print Intervention for African American Women in the Deep South

Levodopa and Exercise for Older Adults With Depression and Psychomotor Slowing

Improving the Recovery and Outcome Every Day After the ICU

Study of BIIB092 in Participants With Progressive Supranuclear Palsy

Study to Evaluate the Efficacy and Safety of GSK239512 in Schizophrenia

MARLINA - T2D : Efficacy, Safety & Modification of Albuminuria in Type 2 Diabetes Subjects With Renal Disease With LINAgliptin

Patients With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard Therapy

Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Expanding and Testing VA Collaborative Care Models for Depression

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year

The Impact of Real-World Vibration Feedback Gait Retraining on Gait Biomechanics in People With Chronic Ankle Instability

Wellness Interventions After Transplant Study

Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients.

A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer