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Showing 1–12 of 12 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Wearing-Off Period of Pharmacological Dilation and Anisocoria

NCT05238233
Conditions
Anisocoria
Interventions
Tropicamide, 1% Pilocarpine, Proparacaine Hydrochloride, Tono pen AVIA, VG4 Gonio, Reichert phoropter
Drug · Device
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Presbyopia
Interventions
Pilocarpine HCl Ophthalmic Solution, Vehicle
Drug · Other
Lead sponsor
Allergan
Industry
Eligibility
40 Years to 55 Years
Enrollment
427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
35
States / cities
Dothan, Alabama • Prescott, Arizona • Sun City, Arizona + 30 more
Conditions
Presbyopia
Interventions
AGN-190584, Vehicle
Drug
Lead sponsor
Allergan
Industry
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
32
States / cities
Dothan, Alabama • Chandler, Arizona • Glendale, California + 27 more
Conditions
Presbyopia
Interventions
Pilocarpine HCl, Vehicle
Drug
Lead sponsor
Allergan
Industry
Eligibility
40 Years to 55 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
23
States / cities
Bakersfield, California • Glendale, California • Inglewood, California + 19 more
Conditions
Presbyopia
Interventions
Pilocarpine Ophthalmic, Placebo
Drug
Lead sponsor
Eyenovia Inc.
Industry
Eligibility
40 Years to 60 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
9
States / cities
Azusa, California • Newport Beach, California • Fort Collins, Colorado + 6 more
Conditions
Presbyopia
Interventions
Pilocarpine Ophthalmic administered with the Optejet dispenser, Placebo administered with the Optejet dispenser
Combination Product
Lead sponsor
Eyenovia Inc.
Industry
Eligibility
40 Years to 55 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
9
States / cities
San Diego, California • Fairfield, Connecticut • Louisville, Kentucky + 6 more
Conditions
Presbyopia
Interventions
Vehicle, Pilocarpine HCl Ophthalmic Solution
Other · Drug
Lead sponsor
Allergan
Industry
Eligibility
40 Years to 55 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
36
States / cities
Chandler, Arizona • Scottsdale, Arizona • Beverly Hills, California + 32 more
Conditions
Presbyopia
Interventions
Phentolamine Ophthalmic Solution 0.75%, Pilocarpine, Placebo
Drug · Other
Lead sponsor
Ocuphire Pharma, Inc.
Industry
Eligibility
40 Years to 64 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
17
States / cities
Laguna Hills, California • Newport Beach, California • Crystal River, Florida + 14 more
Conditions
Glaucoma
Interventions
Pilocarpine, Prednisolone, Ofloxacin
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
30 Years to 100 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
2
States / cities
The Bronx, New York
Conditions
Presbyopia, Glasses, Dry Eye
Interventions
pilocarpine HCL ophthalmic solution
Drug
Lead sponsor
Southern College of Optometry
Other
Eligibility
45 Years to 64 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Medina, Minnesota • Memphis, Tennessee
Conditions
Presbyopia
Interventions
Phentolamine Opthalmic Solution 0.75%, Placebo, Low dose pilocarpine, Low dose pilocarpine vehicle
Drug · Other
Lead sponsor
Ocuphire Pharma, Inc.
Industry
Eligibility
40 Years to 64 Years
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
26
States / cities
Phoenix, Arizona • Azusa, California • Newport Beach, California + 23 more
Conditions
Pupil Constriction
Interventions
NV701, Pilocarpine 1.25% Eye drop
Drug
Lead sponsor
Novus Vision LLC
Industry
Eligibility
40 Years to 55 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Chandler, Arizona • Glendale, California