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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:32 AM EDT

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Showing 49–72 of 325 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: surgical wound closure Clear all
Completed Not applicable Interventional Results available

EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds

NCT03960463
View directory record Official record
Conditions
Surgical Wound, Diabetes, Amputation Wound, Incision Wound, Peripheral Arterial Disease, Breast Cancer, Diabetic Foot
Interventions
Transcu O2®
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional

SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections

NCT03816293
View directory record Official record
Conditions
Surgical Site Infection, Obesity, Diabetes, Cesarean Section Complications
Interventions
Negative Pressure Wound Therapy
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
3,680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
5
States / cities
Atlanta, Georgia • Chicago, Illinois • Iowa City, Iowa + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Results available

Evaluating Advantages of Prevena After Hip and Knee Arthroplasty

NCT01854138
View directory record Official record
Conditions
Infection of Total Hip Joint Prosthesis
Interventions
Prevena Incision Management System
Device
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2018 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Results available

Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections

NCT03021668
View directory record Official record
Conditions
Surgical Site Infection, Pancreatic Neoplasms, Pancreatic Cancer, Chemotherapy Effects, Chemoradiation, Surgical Wound, Wound Complication
Interventions
Prevena Peel & Place Dressing, Standard Closure of the Surgical Incision
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery

NCT01297959
View directory record Official record
Conditions
Infections
Interventions
E-101 Solution 300 GU/ml, Saline solution
Drug
Lead sponsor
Excited States, LLC
Industry
Eligibility
18 Years and older
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
34
States / cities
Mobile, Alabama • Los Angeles, California • Stanford, California + 29 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Oct 2, 2026, 2:32 AM EDT
Terminated Phase 4 Interventional Results available

A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy

NCT02058290
View directory record Official record
Conditions
Bowel Obstruction
Interventions
IV morphine sulfate or Sponsor-approved equivalent, EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Miami, Florida • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 14, 2014 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional

Post Operative Skin Approximation With Cyanoacrylate Based Wound Closure Adhesives

NCT07613892
View directory record Official record
Conditions
Wound Closure, Dehisced Surgical Wounds
Interventions
Evaluating wound closure products to close larger surgical site incisions, Evaluating wound closure products to close smaller surgical site incisions
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Johnstown, Colorado
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Phase 4 Interventional Results available

Subcuticular Suture for Cesarean Skin Incision Closure

NCT02459093
View directory record Official record
Conditions
Complications; Cesarean Section, Surgical Wound Infection
Interventions
poliglecaprone 25 suture, polyglactin 910 suture
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 2, 2026, 2:32 AM EDT
Terminated Phase 4 Interventional

Use of Long-acting Bupivacaine In Lower Extremity Amputation

NCT04360421
View directory record Official record
Conditions
Amputation, Anesthesia, Local, Opioid Use
Interventions
Liposomal bupivacaine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Results available

A Clinical Trial Using Spy Elite System in Planning Tissue Advancement Flaps After Ventral Hernia Repair

NCT01886963
View directory record Official record
Conditions
Ventral Hernia
Interventions
SPY - Unblinded use of SPY Elite, Control - Blinded use of SPY Elite
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intravenous Lidocaine for Cystectomy Procedures

NCT02924480
View directory record Official record
Conditions
Invasive Bladder Cancer
Interventions
Cystectomy, Lidocaine, Saline
Procedure · Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

NCT06939673
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD), Chronic Wounds, Undermined and Tunneling Wounds
Interventions
Acellular Porcine-Derived Wound Matrix
Device
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Coconut Creek, Florida • Tamarac, Florida
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Results available

Comparison of Topical Skin Adhesive to Subcuticular Suture Closure of Implantable Port Incisions

NCT02212977
View directory record Official record
Conditions
Port-A-Cath Placement, Octylcyanoacrylate
Interventions
Octylcyanoacrylate, Suture
Device · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting No phase listed Observational

Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure

NCT06871735
View directory record Official record
Conditions
Bone Graft
Interventions
Acellular matrix, Surgical closure
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Multimodal Pain Management for Cesarean Delivery

NCT02922985
View directory record Official record
Conditions
Pain
Interventions
Intravenous acetominophen, Ketorolac, intramuscular, Bupivacaine, subcutaneous, Normal saline
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Results available

Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds

NCT01050673
View directory record Official record
Conditions
Surgical Wound Dehiscence
Interventions
VERSAJET, Scalpel or blade
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Oct 2, 2026, 2:32 AM EDT
Withdrawn Phase 4 Interventional

ZIPS Study - Zip Incision Approximation vs. STAPLE

NCT02255877
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Zip Surgical Skin Closure, Steel Staples
Device
Lead sponsor
ZipLine Medical Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Oct 2, 2026, 2:32 AM EDT
Suspended Not applicable Interventional

Aesthetic Outcome of Tie-over Bolster Application in Surgical Wounds

NCT05758168
View directory record Official record
Conditions
Scarring
Interventions
Addition of Tie-Over Bolster Dressing
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Recruiting Phase 3 Interventional

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

NCT04678154
View directory record Official record
Conditions
Post Operative Surgical Site Infection
Interventions
Standard of care, Vancomycin and Tobramycin
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 64 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
31
States / cities
Redwood City, California • San Francisco, California • Aurora, Colorado + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures

NCT03891004
View directory record Official record
Conditions
Surgical Wound, Tissue Adhesion
Interventions
Subcuticular Skin Closure, Tissue Adhesives
Procedure · Device
Lead sponsor
St. John Hospital & Medical Center
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 2, 2026, 2:32 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Needle-Aspirated Compression Dressing Following Ostomy Reversal

NCT03703661
View directory record Official record
Conditions
Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
Interventions
Needle-Aspirated Negative Pressure Dressing, Control
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Phase 4 Interventional

Caldolor Versus Caldolor Plus OFIRMEV in Total Knee or Hip Arthroplasty Surgeries

NCT01773005
View directory record Official record
Conditions
Pain
Interventions
Ofirmev, Caldolor
Drug
Lead sponsor
Anita Gupta
Other
Eligibility
18 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Oct 2, 2026, 2:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Hip DAA Closure Techniques

NCT06006572
View directory record Official record
Conditions
Total Hip Replacement, Wound Complication
Interventions
wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive, wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Oct 2, 2026, 2:32 AM EDT
Completed Phase 2 Interventional Results available

Preventing Complications in Cleft Palate Repair With Antibiotics

NCT00760006
View directory record Official record
Conditions
Cleft Palates
Interventions
Unasyn, saline solution
Drug · Other
Lead sponsor
Joseph Losee
Other
Eligibility
3 Months to 18 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 1, 2018 · Synced Oct 2, 2026, 2:32 AM EDT