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ClinicalTrials.gov public records Last synced Oct 14, 2026, 7:13 PM EDT

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Showing 169–192 of 2,710 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Duke University Clear all
Active, not recruiting Not applicable Interventional Results available

Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS

NCT02926911
View directory record Official record
Conditions
DCIS, Ductal Carcinoma in Situ
Interventions
Surgery, Active Monitoring
Other
Lead sponsor
Alliance Foundation Trials, LLC.
Other
Eligibility
40 Years to 99 Years · Female only
Enrollment
997 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
141
States / cities
Anchorage, Alaska • Phoenix, Arizona • Duarte, California + 117 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Weight Poster, Multi-site Study

NCT03128112
View directory record Official record
Conditions
Childhood Obesity
Interventions
Exam room with poster
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
3 Years to 8 Years
Enrollment
965 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
7
States / cities
Huntsville, Alabama • Crestview Hills, Kentucky • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2019 · Synced Oct 14, 2026, 7:13 PM EDT
Completed No phase listed Observational

Transplantation and the Use of Raltegravir in HIV-Infected Patients

NCT01793467
View directory record Official record
Conditions
HIV Positive, Organ Transplant Recipient, Active Wait Listing for Organ Transplant
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
13 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Oct 14, 2026, 7:13 PM EDT
Recruiting Not applicable Interventional

Photon-counting CT in Chest Imaging

NCT07031336
View directory record Official record
Conditions
COPD (Chronic Obstructive Pulmonary Disease)
Interventions
Photon-counting CT, Energy-integrating CT
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Not applicable Interventional Results available

Combining Objective and Subjective Sedation Assessment Tools

NCT00734409
View directory record Official record
Conditions
Critical Illness
Interventions
Bispectral Index (BIS) Monitor
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 29, 2013 · Synced Oct 14, 2026, 7:13 PM EDT
Recruiting Not applicable Interventional

Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History

NCT05867381
View directory record Official record
Conditions
Air Pollution, Atherosclerosis
Interventions
HEPA filtration, Sham filtration
Device
Lead sponsor
University of Southern California
Other
Eligibility
65 Years to 84 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Log2Lose: Incenting Weight Loss and Dietary Self-monitoring in Real-time to Improve Weight Management Among Adults With Obesity

NCT04770909
View directory record Official record
Conditions
Obesity
Interventions
Incentives for dietary self-monitoring and weight loss, Incentives for dietary self-monitoring, Incentives for weight loss
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
706 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Durham, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2

NCT04235309
View directory record Official record
Conditions
Resilience, Aging
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
297 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
3
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 14, 2026, 7:13 PM EDT
Completed No phase listed Observational

Psychiatric Comorbidity

NCT02927652
View directory record Official record
Conditions
Otorhinolaryngologic Diseases
Interventions
Questionnaires
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
463 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer

NCT02990468
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
BMX-001, Radiation Therapy, Cisplatin
Drug · Radiation
Lead sponsor
BioMimetix JV, LLC
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
4
States / cities
San Francisco, California • Gainesville, Florida • Omaha, Nebraska + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Not applicable Interventional

Adaptation and Pilot Testing of a Mindfulness-Based Insomnia and Symptom Management Intervention for Women With Breast Cancer Receiving Treatment in Rural Medically Underserved Areas

NCT06529120
View directory record Official record
Conditions
Breast Cancer
Interventions
Mindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Prince Frederick, Maryland • Henderson, North Carolina • Laurinburg, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Terminated Phase 2 Interventional Results available

ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN

NCT04639024
View directory record Official record
Conditions
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Myeloproliferative Neoplasm (MDS/MPN)
Interventions
ADCT-301
Drug
Lead sponsor
Gwynn Long, M.D.
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Phase 4 Interventional Results available

TissueLink Study During Multi-Level Spine Surgery

NCT01300559
View directory record Official record
Conditions
Low Back Pain
Interventions
Tissuelink device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2013 · Synced Oct 14, 2026, 7:13 PM EDT
Terminated No phase listed Observational

Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip

NCT01759550
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 14, 2026, 7:13 PM EDT
Completed No phase listed Observational

Function and Scoliosis Surgery

NCT02237248
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 14, 2026, 7:13 PM EDT
Completed No phase listed Observational Results available

Patient Attitudes and Preferences for Outcomes of Inflammatory Bowel Disease Therapeutics

NCT02316678
View directory record Official record
Conditions
Colitis, Ulcerative, Inflammatory Bowel Diseases, Crohn's Disease
Interventions
No intervention
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
9,573 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2017 · Synced Oct 14, 2026, 7:13 PM EDT
Recruiting No phase listed Observational

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

NCT06625684
View directory record Official record
Conditions
Glioblastoma
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans

NCT02789241
View directory record Official record
Conditions
Healthy
Interventions
Endotoxin, Placebo
Biological · Other
Lead sponsor
Robert J Noveck, M.D.
Other
Eligibility
18 Years to 40 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Oct 14, 2026, 7:13 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

NCT03276923
View directory record Official record
Conditions
Autoimmune Diseases, Pregnancy Related, Systemic Lupus Erythematosus, Cutaneous Lupus, Rheumatoid Arthritis, Sjogren's Syndrome, Scleroderma
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 14, 2026, 7:13 PM EDT
Terminated Phase 2 Interventional Results available

Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With Bevacizumab

NCT00636805
View directory record Official record
Conditions
Brain Cancer
Interventions
Palonosetron (Aloxi) and Dexamethasone
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2014 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuroimaging Decision Making and Response Inhibition During Smoking Abstinence

NCT00672256
View directory record Official record
Conditions
Smoking
Interventions
Smoking Abstinence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Oct 14, 2026, 7:13 PM EDT
Withdrawn No phase listed Observational

Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability

NCT01028183
View directory record Official record
Conditions
Gastroesophageal Reflux, Presumed Sepsis, Patent Ductus Arteriosus, Chronic Lung Disease, Neurodevelopmental Impairment
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Up to 5 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Accuracy of the O2 MedTech PMS-3000 Monitor

NCT01418079
View directory record Official record
Conditions
Healthy
Interventions
O2 MedTech cerebral oximeter (Oxygen desaturation)
Device
Lead sponsor
O2 MedTech, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 23, 2012 · Synced Oct 14, 2026, 7:13 PM EDT
Completed Phase 1 Interventional

Immunotherapy With CEA(6D) VRP Vaccine (AVX701) in Patients With Stage III Colorectal Cancer

NCT01890213
View directory record Official record
Conditions
Stage III Colon Cancer
Interventions
AVX701
Biological
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 14, 2026, 7:13 PM EDT