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ClinicalTrials.gov public records Last synced Oct 16, 2026, 9:19 PM EDT

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Showing 1–24 of 82 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: McMaster University Clear all
Completed Not applicable Interventional Results available

Increasing the Temporal Window in Individuals With Alcohol Use Disorder

NCT04125238
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Episodic Future Thinking, Control Episodic Thinking
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years to 65 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 16, 2026, 9:19 PM EDT
Active, not recruiting Not applicable Interventional

A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients

NCT03127631
View directory record Official record
Conditions
Prostate Cancer, Cardiovascular Disease
Interventions
Nutrition, Exercise, Smoking cessation, Statin (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin), ACE inhibitor
Behavioral · Drug
Lead sponsor
McMaster University
Other
Eligibility
45 Years and older · Male only
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
4
States / cities
Augusta, Georgia • Kansas City, Kansas • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 16, 2026, 9:19 PM EDT
Completed No phase listed Observational

Incidence of Venous Thromboembolism in Patients Undergoing Major Esophageal Resection

NCT03115541
View directory record Official record
Conditions
Venous Thromboembolism, Thoracic Surgery, Esophageal Cancer
Interventions
Not listed
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Ann Arbor, Michigan • Rochester, Minnesota • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional

D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months

NCT00720915
View directory record Official record
Conditions
Deep Vein Thrombosis, Pulmonary Embolism
Interventions
Discontinue anticoagulant therapy (Negative d-dimer), Continue on anticoagulant therapy (positive d-dimer)
Other
Lead sponsor
McMaster University
Other
Eligibility
18 Years to 75 Years
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Iowa City, Iowa • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2016 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Pilot Study of PHOENIX Wound Matrix® Impact on Chronic DFU Wound Microbiome

NCT04437537
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Bioresorbable 3D electrospun synthetic matrix
Device
Lead sponsor
RenovoDerm
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Northampton, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

Decreasing the Temporal Window in Individuals With Alcohol Use Disorder

NCT04128761
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Scarcity Narrative, Neutral Narrative
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 16, 2026, 9:19 PM EDT
Terminated Phase 3 Interventional

Preemptive Therapy for SARS-Coronavirus-2 (COVID-19 PEP Canada)

NCT04421664
View directory record Official record
Conditions
Corona Virus Infection, SARS-CoV Infection, Coronavirus
Interventions
Hydroxychloroquine, Placebo oral tablet
Drug
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Phase 3 Interventional

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial

NCT03374800
View directory record Official record
Conditions
Gastrointestinal Hemorrhage (Clinically Important, Upper)
Interventions
Placebo (0.9% saline), Pantoprazole
Drug
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
4,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 16, 2026, 9:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

NCT07063732
View directory record Official record
Conditions
High Altitude Hypoxia, Exercise
Interventions
Ketone Monoester (KME), Placebo
Dietary Supplement
Lead sponsor
McMaster University
Other
Eligibility
18 Years to 35 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Bishop, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial

NCT04274530
View directory record Official record
Conditions
Pain, Postoperative, Pain, Acute, Pain, Chronic, Fractures, Closed, Fractures, Open
Interventions
Cognitive Behavioural Therapy
Behavioral
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
1,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Largo, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 16, 2026, 9:19 PM EDT
Recruiting Not applicable Interventional

Pericardiotomy in Cardiac Surgery

NCT06486636
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Cardiac Events
Interventions
Left Posterior Pericardiotomy
Procedure
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 16, 2026, 9:19 PM EDT
Completed No phase listed Observational

Perioperative Anticoagulant Use for Surgery Evaluation Study

NCT02228798
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
3,135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
Aurora, Colorado • Evanston, Illinois • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2019 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Nurse-family Partnership (NFP) Curriculum Study

NCT01372098
View directory record Official record
Conditions
Domestic Violence
Interventions
NFP + IPV intervention
Behavioral
Lead sponsor
McMaster University
Other
Eligibility
16 Years and older · Female only
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2015 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Phase 3 Interventional

Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)

NCT01479283
View directory record Official record
Conditions
Infection, Bone Neoplasms
Interventions
24-Hour Prophylactic Cefazolin* Antibiotic Regimen, 5-Days Prophylactic Cefazolin* Antibiotic Regimen
Drug
Lead sponsor
McMaster University
Other
Eligibility
12 Years and older
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
34
States / cities
Little Rock, Arkansas • Los Angeles, California • Redwood City, California + 26 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 16, 2026, 9:19 PM EDT
Recruiting Not applicable Interventional

Accelerated Flap Coverage in Severe Lower Extremity Trauma

NCT06293469
View directory record Official record
Conditions
Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
Interventions
Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
356 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
7
States / cities
Sacramento, California • Baltimore, Maryland • Largo, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Development of a Questionnaire to Evaluate Patient Expectations for Breast Reconstruction in Women With Breast Cancer or Other Conditions

NCT00471601
View directory record Official record
Conditions
Breast Cancer
Interventions
counseling intervention, questionnaire administration, psychosocial assessment and care, quality-of-life assessment
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
357 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2023
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 16, 2026, 9:19 PM EDT
Completed No phase listed Observational

Detection and Neurological Impact of CerebroVascular Events In Noncardiac Surgery PatIents: A COhort EvaluatioN

NCT01980511
View directory record Official record
Conditions
Covert Postoperative Stroke
Interventions
Not listed
Lead sponsor
McMaster University
Other
Eligibility
65 Years and older
Enrollment
1,116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Phase 3 Interventional

Canadian Oxygen Trial (COT)

NCT00637169
View directory record Official record
Conditions
Respiratory Insufficiency of Prematurity
Interventions
Titration of oxygen therapy
Other
Lead sponsor
McMaster University
Other
Eligibility
Up to 24 Hours
Enrollment
1,201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
3
States / cities
Stony Brook, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

Comparing Total Hip Arthroplasty and Hemi-Arthroplasty on Secondary Procedures and Quality of Life in Adults With Displaced Hip Fractures

NCT00556842
View directory record Official record
Conditions
Hip Fractures, Femoral Neck Fractures
Interventions
Total hip arthroplasty, Hemi-arthroplasty
Device
Lead sponsor
McMaster University
Other
Eligibility
50 Years and older
Enrollment
1,495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Phase 2 Interventional Results available

Optimal Vitamin D3 Supplementation Strategies for Acute Fracture Healing

NCT02786498
View directory record Official record
Conditions
Fracture
Interventions
Vitamin D3, Placebo
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 50 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 16, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Fluid Lavage of Open Wounds

NCT00788398
View directory record Official record
Conditions
Open Fracture Wounds
Interventions
Saline Solution, Soap solution, Gravity Flow Irrigation, Low Pressure Irrigation, High Pressure
Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
14 Years to 85 Years
Enrollment
2,540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
14
States / cities
Birmingham, Alabama • Orange, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Oct 16, 2026, 9:19 PM EDT
Recruiting Not applicable Interventional

Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

NCT06957366
View directory record Official record
Conditions
Atrial Fibrillation (AF), VTE
Interventions
PAUSE Perioperative DOAC Management, ASRA Perioperative DOAC Management
Other
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
920 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Hartford, Connecticut • Evanston, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated May 9, 2025 · Synced Oct 16, 2026, 9:19 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Bupivacaine Epiphora Trial

NCT03266081
View directory record Official record
Conditions
Epiphora, Ptosis
Interventions
0.75% bupivacaine
Drug
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 16, 2026, 9:19 PM EDT
Recruiting No phase listed Observational

Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

NCT05347238
View directory record Official record
Conditions
Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
Interventions
Dopamine, Norepinephrine
Drug
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
21 Weeks to 32 Weeks
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Phoenix, Arizona • Dayton, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 16, 2026, 9:19 PM EDT