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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:55 AM EST

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Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.

Filters: Sponsor: Medtronic Cardiovascular Clear all

Conditions: Dysfunctional RVOT Conduits in Patients With Congenital Heart Defects
Interventions: Melody Transcatheter Pulmonary Valve PB1016; Device
Lead sponsor: Medtronic Heart Valves; Industry
Eligibility: Not listed
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 5
States / cities: Los Angeles, California • Detroit, Michigan • Columbus, Ohio + 2 more

Conditions: Severe Aortic Stenosis
Interventions: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI); Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: Not listed
Enrollment: 782 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2025
U.S. locations: 43
States / cities: Phoenix, Arizona • Los Angeles, California • Palo Alto, California + 33 more

Conditions: Coronary Angiography, Transcatheter Aortic Valve Replacement
Interventions: Coronary Angiography; Diagnostic Test
Lead sponsor: University of British Columbia; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Harrisburg, Pennsylvania

Conditions: Dysfunctional Right Ventricular Outflow Tract (RVOT) Conduit
Interventions: Melody® Transcatheter Pulmonary Valve; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: Not listed
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 10
States / cities: San Diego, California • Oak Lawn, Illinois • Ann Arbor, Michigan + 7 more

Conditions: Coronary Disease, Coronary Stenosis
Interventions: FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent; Procedure · Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2024
U.S. locations: 13
States / cities: Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more

Conditions: Congenital Heart Disease, Tetralogy of Fallot
Interventions: Native Outflow Tract TPV; Device
Lead sponsor: Medtronic Heart Valves; Industry
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 2
States / cities: Boston, Massachusetts • Columbus, Ohio

Conditions: Tricuspid Regurgitation
Interventions: Intrepid™ TTVR System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2031
U.S. locations: 20
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more

Conditions: Abdominal Aortic Aneurysms
Interventions: TALENT Aortic Cuff Abdominal Stent Graft; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 50
States / cities: Montgomery, Alabama • Oakland, California • San Jose, California + 42 more

Conditions: Arteriosclerosis of Coronary Artery Bypass Graft
Interventions: Minimally invasive coronary artery bypass graft surgery; Procedure
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Staten Island, New York

Conditions: Congenital Heart Defects, Dysfunctional Right Ventricular Outflow Tract Conduits
Interventions: Transcatheter Pulmonary Valve replacement; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 5 Years and older
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2020
U.S. locations: 5
States / cities: Miami, Florida • Boston, Massachusetts • New York, New York + 2 more

Conditions: Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Interventions: Medtronic Endurant II or Endurant IIs Stent Graft System, Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 20 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2031
U.S. locations: 32
States / cities: Loma Linda, California • Newport Beach, California • Orange, California + 29 more

Conditions: Symptomatic Aortic Stenosis
Interventions: Evolut™ PRO and Evolut™ PRO+ System (Evolut™ FX System for the addendum); Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: Not listed
Enrollment: 1,127 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 37
States / cities: Birmingham, Alabama • San Francisco, California • Hartford, Connecticut + 32 more

Conditions: Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency
Interventions: Contour 3D® implant for tricuspid valve repair, Tri-Ad® implant for tricuspid valve repair; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 3
States / cities: Aventura, Florida • Ann Arbor, Michigan • Asheville, North Carolina

Conditions: Aortic Aneurysm, Thoracic, Chronic Type B Dissection
Interventions: Valiant Mona LSA Thoracic Stent Graft System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Severe Aortic Stenosis
Interventions: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI); Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: Not listed
Enrollment: 2,777 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 45
States / cities: Phoenix, Arizona • Los Angeles, California • Mountain View, California + 35 more

Conditions: Abdominal Aneurysm
Interventions: AneuRx Stent Graft; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 349 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2009
U.S. locations: 8
States / cities: Tucson, Arizona • Royal Oak, Michigan • Morristown, New Jersey + 5 more

Conditions: Severe Tricuspid Regurgitation
Interventions: Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System, Edwards EVOQUE Tricuspid Valve Replacement (TTVR) System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 1,186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2041
U.S. locations: 20
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more

Conditions: Blunt Thoracic Aortic Injury
Interventions: Valiant Thoracic Stent Graft with the Captivia Delivery System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 23
States / cities: Birmingham, Alabama • Los Angeles, California • Torrance, California + 20 more

Conditions: Congenital Heart Disease, Tetrology of Fallot, RVOT Anomaly, Pulmonary Regurgitation
Interventions: Harmony TPV System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: Not listed
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2035
U.S. locations: 19
States / cities: Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 15 more

Conditions: Bicuspid Aortic Valve
Interventions: Medtronic TAVR Systems; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 60 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2030
U.S. locations: 25
States / cities: Phoenix, Arizona • La Jolla, California • Thousand Oaks, California + 21 more

Conditions: Thoracic Aortic Aneurysms
Interventions: Talent Thoracic Stent Graft System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 349 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 26
States / cities: Los Angeles, California • Torrance, California • Washington D.C., District of Columbia + 22 more

Conditions: Abdominal Aortic Aneurysms (AAA)
Interventions: Aptus Endovascular AAA Repair System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 21 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 2
States / cities: Albany, New York • Philadelphia, Pennsylvania

Conditions: Moderate Aortic Valve Stenosis
Interventions: Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT); Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 65 Years and older
Enrollment: 650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2034
U.S. locations: 52
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 47 more

Conditions: Mitral Valve Insufficiency
Interventions: Twelve TMVR Implant, Medtronic Intrepid™ Transcatheter Transfemoral Mitral Valve Replacement System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2028
U.S. locations: 21
States / cities: Phoenix, Arizona • Los Angeles, California • Atlanta, Georgia + 12 more

Search by objective public record fields.

Melody PB1016 Surveillance Study

Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement

Coronary Access After Supra-Annular THV Implantation

Melody® Transcatheter Pulmonary Valve Post-Approval Study

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

Study of the Native Outflow Tract Transcatheter Pulmonary Valve (TPV)

TTVR Early Feasibility Study

Talent Aortic Cuff Stent Graft System Compassionate Use Registry

Graft Patency Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Via Minimally Invasive Coronary Surgery

Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort

Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

Optimize PRO Study

Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial

Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

AneuRx Post Market Study in the Treatment of AAA

Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation

Study to Determine if the Valiant Stent Graft is Safe and Effective in Treating Patients Who Have a Blunt Thoracic Aortic Injury

Harmony TPV Post-Approval Study

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)

The Pivotal Study of the Aptus Endovascular AAA Repair System

Evolut™ EXPAND TAVR II Pivotal Trial

Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System