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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:03 PM EDT

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Showing 73–96 of 298 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: AF Clear all
Not yet recruiting Not applicable Interventional

A Study to Predict Atrial Fibrillation (AF) Burden in Participants With PAF and PsAF Treated With the VARIPULSE™ PFA Catheter

NCT07788989
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
VARIPULSE Catheter System (PVI), VARIPULSE Catheter System (PVI and PWI)
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Enrolling by invitation Not applicable Interventional

Out-of-office Monitoring for Rhythms Of Normal Versus Atrial Fibrillation

NCT07582523
View directory record Official record
Conditions
Atrial Fibrillation (AF), Hypertension (HTN), High Blood Pressure
Interventions
Blood Pressure Monitor Without AFib Detection, Blood Pressure Monitor With AFib Detection
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
1,910 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Phase 3 Interventional

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Abelacimab, Placebo
Biological · Drug
Lead sponsor
Anthos Therapeutics, Inc.
Industry
Eligibility
65 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
174
States / cities
Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 143 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Not applicable Interventional

Tolerance and Efficacy of a Predigested, High Protein, High Omega 3 Fat Enteral Feeding Formula Versus a Standard Formula In Multiple Intensive Care Unit Settings

NCT01448135
View directory record Official record
Conditions
Critical Illness, Enteral Feeding
Interventions
VITAL AF, Osmolite 1.2
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Phase 2 Interventional

TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

NCT06802081
View directory record Official record
Conditions
Atrial Fibrillation, Obesity
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Phase 3 Interventional

Concomitant Treatment of Permanent Atrial Fibrillation

NCT00566787
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Surgical bipolar radiofrequency ablation using the AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
10
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Grand Rapids, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Oct 21, 2026, 2:03 PM EDT
Enrolling by invitation Not applicable Interventional

Storytelling for Reducing Gap in Anticoagulation Use in African Americans With Atrial Fibrillation

NCT05997914
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Adherence, Medication, Anticoagulants and Bleeding Disorders, Stroke, Bleeding, Narration
Interventions
Storytelling Intervention
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Jacksonville, Florida • Worcester, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed No phase listed Observational

RATE Registry - Registry of Atrial Tachyarrhythmia/Atrial Fibrillation (AT/AF) Episodes in the Cardiac Rhythm Management (CRM) Device Population

NCT00837798
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
CRM Device
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
5,379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 21, 2026, 2:03 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter

NCT01710150
View directory record Official record
Conditions
Typical Atrial Flutter, Risk Factors With Future Development of Atrial Flutter
Interventions
CTI ablation alone, CTI ablation and Pulmonary vein isolation (PVI)
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 21, 2026, 2:03 PM EDT
Terminated Phase 3 Interventional Results available

Atorvastatin Therapy for the Prevention of Atrial Fibrillation (SToP-AF)

NCT00252967
View directory record Official record
Conditions
Atrial Fibrillation, Inflammation
Interventions
Atorvastatin, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Oct 21, 2026, 2:03 PM EDT
Completed No phase listed Observational Results available

Prediction of the COBRRA AF Anticoagulant Trial in Healthcare Claims Data

NCT05256797
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Rivaroxaban, Apixaban
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 120 Years
Enrollment
353,980 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Active, not recruiting No phase listed Observational

P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation

NCT07471308
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System, Atrial Fibrillation (Paroxysmal), Pulmonary Vein Isolation
Interventions
AF Recurrence RIsk Assessment post pulmonary vein isolation
Device
Lead sponsor
CathVision ApS
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Active, not recruiting No phase listed Observational

Real-world Safety and Effectiveness Registry of Catheter Ablation of Paroxysmal Atrial Fibrillation as Initial Control Therapy With the Thermocool SmartTouch SF Catheter (A Sub-study of REAL AF Registry)

NCT07092774
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation (PAF)
Interventions
Ablation
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
Birmingham, Alabama • Ventura, California • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Terminated Not applicable Interventional

MultiPulse Therapy (MPT) for AF (US)

NCT05055921
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
Multi Pulse Therapy as delivered from the Cardialen External Stimulation System
Device
Lead sponsor
Cardialen, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
Minneapolis, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Not applicable Interventional

Prospective Remapping With Concomitant Left Atrial Appendage Occlusion to Ensure Durable Electroporation Study

NCT07620262
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Remapping Procedure
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bay Shore, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Investigate if Early Atrial Fibrillation (AF) Diagnosis Reduces Risk of Events Like Stroke in the Real-World

NCT04276441
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Heart healthy Engagement Program with the Apple Watch Series 5 or later, Anti-Coagulation Adherence Module with the Apple Watch Series 5 or later
Device
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
65 Years and older
Enrollment
34,244 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
San Mateo, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Stroke Feasibility Study

NCT01997905
View directory record Official record
Conditions
Atrial Fibrillation, AFib
Interventions
AtriClip LAA Exclusion Device
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
7
States / cities
St. Helena, California • Miami, Florida • Indianapolis, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF

NCT06099730
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulsed Field Ablation (PFA)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
6
States / cities
Jonesboro, Arkansas • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Withdrawn No phase listed Observational

PVI Using Cryoablation Alone in Paroxysmal AF Patients Converted From Persistent AF With Dofetilide

NCT01877486
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
Ablation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Oct 21, 2026, 2:03 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Empowering Veterans in Research Effectively Using Virtual Engagement Tools

NCT07741955
View directory record Official record
Conditions
Atrial Fibrillation (AF), Cardiovascular Diseases
Interventions
AI-Generated Avatar Videos for Clinical Trial Outreach
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 21, 2026, 2:03 PM EDT
Completed Phase 3 Interventional

Effect of Amiodarone on the Procedure Outcome in Long-standing Persistent Atrial Fibrillation Undergoing Pulmonary Vein Antral Isolation

NCT01173809
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Amiodarone
Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2014 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting No phase listed Observational

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation

NCT06056271
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
AF Ablation
Device
Lead sponsor
Volta Medical
Industry
Eligibility
21 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Evanston, Illinois • Overland Park, Kansas • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting No phase listed Observational

MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)

NCT05978466
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
CorVita Science Foundation
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 21, 2026, 2:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BoxX-NoAF Clinical Trial

NCT06989775
View directory record Official record
Conditions
Post Operative Atrial Fibrillation, Atrial Fibrillation, Postoperative
Interventions
Isolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
65 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
33
States / cities
Scottsdale, Arizona • Jonesboro, Arkansas • San Diego, California + 27 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 21, 2026, 2:03 PM EDT