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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Acute Ischemic Stroke Clear all
Completed Not applicable Interventional

pRESET for Occlusive Stroke Treatment

NCT03994822
View directory record Official record
Conditions
Brain Diseases, Cardiovascular Diseases, Central Nervous System Diseases, Cerebrovascular Disorders, Ischemia, Nervous System Diseases, Pathologic Processes, Stroke, Ischemic, Stroke, Acute, Vascular Diseases
Interventions
Mechanical Thrombectomy using the pRESET Thrombectomy device, Mechanical Thrombectomy using the Solitaire Revascularization Device
Device
Lead sponsor
phenox Inc.
Industry
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
19
States / cities
Scottsdale, Arizona • Santa Monica, California • Coral Gables, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Not applicable Interventional

Shared Decision Making to Improve Goals-of-Care Decisions for Families of Severe Acute Brain Injury Patients

NCT03833375
View directory record Official record
Conditions
Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage
Interventions
Decision Aid
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
New Haven, Connecticut • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 2 Interventional Results available

A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel

NCT03766581
View directory record Official record
Conditions
Acute Ischemic Stroke, Transient Ischemic Attack (TIA)
Interventions
BMS-986177, Placebo, Clopidogrel, Aspirin
Drug · Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
40 Years and older
Enrollment
2,366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
66
States / cities
Birmingham, Alabama • Glendale, California • Long Beach, California + 51 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2023 · Synced Jun 7, 2026, 7:59 AM EDT
Suspended Phase 3 Interventional

Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina

NCT00353067
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
veliflapon (DG-031)
Drug
Lead sponsor
deCODE genetics
Industry
Eligibility
35 Years and older
Enrollment
3,450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
11
States / cities
Montgomery, Alabama • Jacksonville, Florida • Melrose Park, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2006 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 2 Interventional Results available

Glucose Regulation in Acute Stroke Patients (GRASP) Study

NCT00282867
View directory record Official record
Conditions
Stroke, Hyperglycemia
Interventions
IV glucose insulin and potassium, GIK, standard care
Drug · Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Augusta, Georgia • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2009 · Synced Jun 7, 2026, 7:59 AM EDT
Active, not recruiting Phase 3 Interventional

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

NCT05702034
View directory record Official record
Conditions
Ischemic Stroke; Ischemic Attack, Transient
Interventions
Milvexian, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
40 Years and older
Enrollment
12,532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
127
States / cities
Mesa, Arizona • Tucson, Arizona • Fayetteville, Arkansas + 102 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 1 Interventional Results available

The Capillary Index Score Trial

NCT02618031
View directory record Official record
Conditions
Acute Stroke, Brain Ischemia, Ischemic Stroke
Interventions
Endovascular Treatment (EVT)
Procedure
Lead sponsor
Firas Al-Ali
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
6
States / cities
Atlanta, Georgia • New York, New York • Rochester, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jun 7, 2026, 7:59 AM EDT
Recruiting Not applicable Interventional

Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe

NCT06825897
View directory record Official record
Conditions
Stroke, Acute
Interventions
Conventional Triage for Mechanical Thrombectomy, Direct Transfer to Angiography Suite (DTAS
Other
Lead sponsor
Santiago Ortega Gutierrez
Other
Eligibility
18 Years and older
Enrollment
2,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
6
States / cities
Iowa City, Iowa • Detroit, Michigan • Wyoming, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 2Phase 3 Interventional

ACTISAVE: ACuTe Ischemic Stroke Study Evaluating Glenzocimab Used as Add-on Therapy Versus placEbo

NCT05070260
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Intravenous glenzocimab (ACT017) 1000 mg, Intravenous Placebo
Drug
Lead sponsor
Acticor Biotech
Industry
Eligibility
18 Years and older
Enrollment
438 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
9
States / cities
Bradenton, Florida • St. Petersburg, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jun 7, 2026, 7:59 AM EDT
Terminated Not applicable Interventional Results available

TEAMS-BP (The Enhancement of Social Networks to Augment Management of Stroke-Blood Pressure)

NCT05258890
View directory record Official record
Conditions
Stroke, Acute Ischemic, Hypertension
Interventions
Social Network Group Counseling, Individual Counseling
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Not applicable Interventional

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion

NCT00624000
View directory record Official record
Conditions
Ischemic Stroke
Interventions
IV tpa (Alteplase) vs IA tpa (Alteplase)
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
19 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2011 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator)

NCT00044057
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
YM872 (zonampanel), t-PA (alteplase)
Drug
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
94
States / cities
Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 78 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2006 · Synced Jun 7, 2026, 7:59 AM EDT
Withdrawn Phase 1 Interventional

Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention

NCT05032781
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
Intra-arterial cold saline, minocycline, and magnesium
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Not applicable Interventional Results available

Enoxaparin Versus Aspirin in Patients With Cancer and Stroke

NCT01763606
View directory record Official record
Conditions
Cancer Patients First-ever Acute Ischemic Stroke
Interventions
Enoxaparin, Aspirin
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 3 Interventional Results available

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin

NCT01225562
View directory record Official record
Conditions
Myocardial Infarction, Cardiovascular Death, Atherothrombosis, Stroke
Interventions
Ticagrelor 90 mg, Ticagrelor 60 mg, Ticagrelor Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
50 Years to 130 Years
Enrollment
21,379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
250
States / cities
Alexander City, Alabama • Athens, Alabama • Birmingham, Alabama + 247 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2016 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Not applicable Interventional Results available

Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke

NCT06042179
View directory record Official record
Conditions
Stroke, Stroke, Acute, Stroke, Ischemic
Interventions
Frequent PT, Intense PT
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jun 7, 2026, 7:59 AM EDT
Withdrawn Phase 1 Interventional

IVIG in Acute Ischemic Stroke: A Pilot Study

NCT01628055
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Privigen, Normal Saline
Biological · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
45 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 10, 2013 · Synced Jun 7, 2026, 7:59 AM EDT
Recruiting Not applicable Interventional

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

NCT06094478
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke, Acute, Hemorrhagic Stroke
Interventions
HI-SPEED Protocol
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
8
States / cities
New Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Not applicable Interventional

REperfusion With Cooling in CerebraL Acute IscheMia II

NCT03804060
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Thermogard XP3, Recanalization only
Device · Procedure
Lead sponsor
ZOLL Circulation, Inc., USA
Industry
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
8
States / cities
Marietta, Georgia • Honolulu, Hawaii • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jun 7, 2026, 7:59 AM EDT
Completed No phase listed Observational

Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)

NCT02014896
View directory record Official record
Conditions
Ischemic Stroke, Atrial Fibrillation, Transient Ischemic Attacks, Transient Cerebrovascular Events, Thrombotic Stroke, Stroke of Basilar Artery, Cardioembolic Stroke
Interventions
Biomarker blood draw
Other
Lead sponsor
Ischemia Care LLC
Industry
Eligibility
18 Years and older
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
22
States / cities
Sacramento, California • San Francisco, California • Detroit, Michigan + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Not applicable Interventional

Stroke Telemedicine for Arizona Rural Residents Trial

NCT00829361
View directory record Official record
Conditions
Stroke, Cerebral Infarction, Vascular Diseases, Brain Ischemia, Brain Infarction, Brain Diseases, Cerebrovascular Disorders
Interventions
Telemedicine
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years
Enrollment
447 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Jun 7, 2026, 7:59 AM EDT
Completed Phase 4 Interventional Results available

SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke

NCT03263117
View directory record Official record
Conditions
Stroke
Interventions
Sedation, General Anesthesia (GA), Intra-arterial Thrombectomy
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 90 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
11
States / cities
Indianapolis, Indiana • Iowa City, Iowa • Louisville, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jun 7, 2026, 7:59 AM EDT
Recruiting No phase listed Observational

Stroke Recovery Initiative - Registry for Stroke Research Studies

NCT03318432
View directory record Official record
Conditions
Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke, Subarachnoid Hemorrhage, Cerebral Ischemia, Cerebral Infarction, Cerebral Stroke, Cerebral Vascular Accident
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jun 7, 2026, 7:59 AM EDT
Completed No phase listed Observational

Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

NCT02446587
View directory record Official record
Conditions
Stroke, Ischemic Stroke
Interventions
Mechanical Thrombectomy
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
9
States / cities
Stanford, California • Orlando, Florida • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jun 7, 2026, 7:59 AM EDT