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Showing 1–24 of 294 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Acute Ischemic Stroke Clear all
Completed Phase 3 Interventional

A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke

NCT05686070
View directory record Official record
Conditions
Prevention of Ischemic Stroke, Acute Non-cardioembolic Ischemic Stroke, High-risk Transient Ischemic Attack
Interventions
Asundexian (BAY2433334), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
12,327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
108
States / cities
Fairhope, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 87 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 22, 2026, 4:22 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

A Feasibility Study for Randomization of Code Stroke Imaging Strategies

NCT06270927
View directory record Official record
Conditions
Brain Ischemia
Interventions
MRI, CT
Diagnostic Test
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 120 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 22, 2026, 4:22 PM EDT
Recruiting Not applicable Interventional

SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

NCT03737786
View directory record Official record
Conditions
Acute Stroke
Interventions
Tight control of end-tidal CO2 levels
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 110 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Jul 22, 2026, 4:22 PM EDT
Terminated Phase 3 Interventional Results available

Interventional Management of Stroke (IMS) III Trial

NCT00359424
View directory record Official record
Conditions
Stroke
Interventions
IV rt-PA alone, endovascular therapy
Drug · Other
Lead sponsor
Joseph Broderick
Other
Eligibility
18 Years to 82 Years
Enrollment
656 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
49
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 39 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2013 · Synced Jul 22, 2026, 4:22 PM EDT
Completed Not applicable Interventional

Cranial Ultrasound for Prehospital ICH Diagnosis

NCT05492474
View directory record Official record
Conditions
Intracerebral Hemorrhage, Acute Ischemic Stroke
Interventions
Cranial Point of Care Ultrasound
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Jul 22, 2026, 4:22 PM EDT
Completed No phase listed Observational Results available

Systematic Evaluation of Patients Treated With Stroke Devices for Acute Ischemic Stroke (STRATIS) Registry

NCT02239640
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Not listed
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
Not listed
Enrollment
984 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
55
States / cities
Phoenix, Arizona • Tucson, Arizona • Irvine, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Jul 22, 2026, 4:22 PM EDT
Completed No phase listed Observational

Telestroke for Comprehensive Transient Ischemic Attack Care in Acute Stroke Ready Hospitals

NCT03724110
View directory record Official record
Conditions
Transient Ischemic Attack
Interventions
Telestroke
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
5
States / cities
Burnsville, Minnesota • Grand Rapids, Minnesota • Hibbing, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Jul 22, 2026, 4:22 PM EDT
Not yet recruiting Phase 2 Interventional

Safety and Efficacy of J147 in Acute Ischemic Stroke

NCT07430917
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
J147 Emulsion for Injection, Placebo
Drug · Other
Lead sponsor
Abrexa Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 22, 2026, 4:22 PM EDT
Withdrawn Phase 1 Interventional

IVIG in Acute Ischemic Stroke: A Pilot Study

NCT01628055
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Privigen, Normal Saline
Biological · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
45 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 10, 2013 · Synced Jul 22, 2026, 4:22 PM EDT
Completed Phase 1 Interventional

Safety Study of Interferon Beta 1a to for Acute Stroke

NCT00097318
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Interferon beta-1a
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 4:22 PM EDT
Recruiting Phase 2 Interventional

A Study of TAK-755 in Adults With Acute Ischemic Stroke

NCT07392450
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
TAK-755, Placebo
Biological · Other
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 80 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 22, 2026, 4:22 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Hypothermia in Acute Stroke With Thrombolysis Imaging Evaluation of Revascularization

NCT01778855
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
IV t-PA and normothermia, IV-tPA and hypothermia
Other · Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
22 Years to 82 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Los Angeles, California • San Diego, California • Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Jul 22, 2026, 4:22 PM EDT
Completed Not applicable Interventional Results available

Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage

NCT04027049
View directory record Official record
Conditions
Intracerebral Hemorrhage, Acute Ischemic Stroke
Interventions
Supine cycle ergometry of the lower extremities
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Jul 22, 2026, 4:22 PM EDT
Withdrawn Phase 2 Interventional

Study to Evaluate The Safety and Efficacy of Balovaptan in Participants With Acute Ischemic Stroke at a High Risk of Developing Malignant Brain Edema

NCT05399550
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Balovaptan, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Jul 22, 2026, 4:22 PM EDT
Completed Not applicable Interventional Results available

The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System

NCT04129125
View directory record Official record
Conditions
Ischemic Stroke, Acute Stroke
Interventions
Zoom Reperfusion System
Device
Lead sponsor
Imperative Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
28
States / cities
Huntsville, Alabama • Tucson, Arizona • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jul 22, 2026, 4:22 PM EDT
Completed No phase listed Observational

Predicting the Development of Myocardial Depression in Acute Neurological Patients

NCT03801694
View directory record Official record
Conditions
Myocardial Depression, Takotsubo Syndrome, Subarachnoid Hemorrhage, Acute Ischemic Stroke
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
50 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Jul 22, 2026, 4:22 PM EDT
Not yet recruiting No phase listed Observational

Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)

NCT07013396
View directory record Official record
Conditions
Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke, Acute Ischemic Stroke, Cardioembolic Stroke, Vasogenic Cerebral Edema
Interventions
Transcranial Doppler (TCD) examination
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 4:22 PM EDT
Completed Not applicable Interventional

Concentric Retriever Device (CRD) in Acute Ischemic Stroke

NCT00203710
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Concentric Retriever Device
Device
Lead sponsor
Sidney Starkman
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Jul 22, 2026, 4:22 PM EDT
Recruiting Not applicable Interventional

Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe

NCT06825897
View directory record Official record
Conditions
Stroke, Acute
Interventions
Conventional Triage for Mechanical Thrombectomy, Direct Transfer to Angiography Suite (DTAS
Other
Lead sponsor
Santiago Ortega Gutierrez
Other
Eligibility
18 Years and older
Enrollment
2,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
6
States / cities
Iowa City, Iowa • Detroit, Michigan • Wyoming, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 22, 2026, 4:22 PM EDT
Not yet recruiting No phase listed Observational

Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital

NCT07474675
View directory record Official record
Conditions
Stroke Code, Large Vessel Occlusion, Acute Ischemic Stroke
Interventions
Point of Care Rapid Assay
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Years to 21 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 22, 2026, 4:22 PM EDT
Completed No phase listed Observational

The PERFusion Use in Stroke Evaluation Study

NCT01387113
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Computed tomography perfusion imaging
Other
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Jul 22, 2026, 4:22 PM EDT
Withdrawn Not applicable Interventional

Reperfusion With Cooling in Cerebral Acute Ischemia II

NCT01728649
View directory record Official record
Conditions
Ischemic Stroke, Hypothermia
Interventions
Mild Hypothermia
Other
Lead sponsor
WellStar Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Jul 22, 2026, 4:22 PM EDT
Completed Phase 2 Interventional Results available

Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain.

NCT04304508
View directory record Official record
Conditions
Acute Non-cardioembolic Ischemic Stroke
Interventions
BAY2433334, BAY2433334 matching placebo
Drug · Other
Lead sponsor
Bayer
Industry
Eligibility
45 Years and older
Enrollment
1,808 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Tampa, Florida • Golden Valley, Minnesota • Kansas City, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Jul 22, 2026, 4:22 PM EDT
Not listed Phase 2 Interventional

Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular Intervention

NCT01455935
View directory record Official record
Conditions
Stroke
Interventions
Anti-platelets and statin, alteplase, intra arterial intervention
Drug · Procedure
Lead sponsor
Jacobs Neurological Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2012 · Synced Jul 22, 2026, 4:22 PM EDT