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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alzheimers Clear all
Recruiting Not applicable Interventional

Brain Stimulation and Cognitive Training for MCI

NCT07526740
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Mild Neurocognitive Disorder, Neurocognitive Disorders, Cognitive Dysfunction, Cognition Disorders
Interventions
Accelerated iTBS, Computerized Cognitive Training, Sham Computerized Cognitive Training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
60 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Terminated Not applicable Interventional

Treating Alzheimer's and Dementia With D-ribose

NCT02260141
View directory record Official record
Conditions
Alzheimers, Dementia
Interventions
d-ribose
Dietary Supplement
Lead sponsor
Practitioners Alliance Network
Other
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Kailua, Hawaii
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of the SmartPrompt for Improving Everyday Function in Dementia

NCT04313582
View directory record Official record
Conditions
Dementia, Dementia, Vascular, Dementia Alzheimers, Dementia, Mixed, Dementia, Mild, Dementia of Alzheimer Type, Mild Cognitive Impairment, Mild Dementia
Interventions
SmartPrompt smartphone application
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

The STEP 4Life Trial

NCT05069155
View directory record Official record
Conditions
Alzheimer Disease, At Risk, Alzheimer Disease, Protection Against, Dementia
Interventions
Gamification
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
55 Years to 75 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 25, 2026, 5:55 AM EDT
Terminated Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Gantenerumab in Participants at Risk for or at the Earliest Stages of Alzheimer's Disease (AD)

NCT05256134
View directory record Official record
Conditions
Alzheimers Disease
Interventions
Gantenerumab, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
60 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
32
States / cities
Phoenix, Arizona • Sun City, Arizona • Tucson, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MASC: Reducing Stress for Caregivers

NCT05847153
View directory record Official record
Conditions
Alzheimer Disease and Related Dementias, Dementia Alzheimers
Interventions
MASC
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Use of [123I] AV39 and SPECT Imaging as a Marker of Protein Disposition in Subjects With Alzheimer Disease Compared to Healthy Subjects

NCT00439010
View directory record Official record
Conditions
Alzheimers Disease
Interventions
[123I] AV 39
Drug
Lead sponsor
Molecular NeuroImaging
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 23, 2008 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Phase 2Phase 3 Interventional

Enhanced CBTi for Older Adult Sleep and Cognition

NCT05015803
View directory record Official record
Conditions
Insomnia, Alzheimers Disease Related Dementias
Interventions
CBTi with Application, CBTi, Sleep Hygiene Education
Combination Product · Behavioral
Lead sponsor
Penn State University
Other
Eligibility
60 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Sep 25, 2026, 5:55 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

NCT05552157
View directory record Official record
Conditions
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Interventions
Remternetug (SC), Matching Placebo (Remternetug)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2034
U.S. locations
13
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Recruiting Phase 2 Interventional

Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease

NCT04902703
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Sargramostim, Saline - placebo comparator
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
60 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Enrolling by invitation Not applicable Interventional

The Nightlight Falls Prevention Study

NCT05973448
View directory record Official record
Conditions
Aging, Alzheimer Disease, Dementia Alzheimers, Dementia of Alzheimer Type, Fall Injury
Interventions
Novel Lighting Condition, Control Lighting Condition
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Persons With Dementia and Their Extended Family Caregivers

NCT04863859
View directory record Official record
Conditions
Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type, Dementia Severe
Interventions
Not listed
Lead sponsor
Karen Roberto
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia

NCT06922188
View directory record Official record
Conditions
Financial Hardship, Alzheimer's Disease (AD), Alzheimer's Disease and Related Dementia (ADRD)
Interventions
Not listed
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
2,460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Phase 4 Interventional Results available

Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care

NCT01993836
View directory record Official record
Conditions
Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
Interventions
Total intravenous anesthesia with propofol, General anesthesia with isoflurane
Drug
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 25, 2026, 5:55 AM EDT
Recruiting Phase 3 Interventional

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

NCT07169578
View directory record Official record
Conditions
Alzheimers Disease
Interventions
Trontinemab, Placebo
Drug · Other
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
50 Years to 90 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
35
States / cities
Birmingham, Alabama • Sun City, Arizona • Irvine, California + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Polyphenols and Cognitive Decline

NCT06507254
View directory record Official record
Conditions
Cognitive Decline, Cognitive Dysfunction
Interventions
Polyphenol Supplement, Placebo Supplement
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Phase 4 Interventional Results available

The Feasibility of Florbetapir Quantitation

NCT01946243
View directory record Official record
Conditions
Alzheimers Disease
Interventions
Florbetapir F18
Drug
Lead sponsor
Avid Radiopharmaceuticals
Industry
Eligibility
Not listed
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2015 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Advance Planning for Home Services for Seniors

NCT02256072
View directory record Official record
Conditions
Alzheimers, Falls, Aging in Place
Interventions
Plan Your Lifespan Website, Go4Life Website
Other
Lead sponsor
Northwestern University
Other
Eligibility
65 Years and older
Enrollment
385 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Chicago, Illinois • Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 25, 2026, 5:55 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Assessing Cognitive Decline at Home

NCT06704971
View directory record Official record
Conditions
Mild Cognitive Impairment, Mild Dementia, Dementia Alzheimers, Dementia, Memory Impairment, NPS
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

A Community-Based Screening Program to Identify Participants at High Risk for Amyloid Pathology

NCT06043700
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
No Intervention
Other
Lead sponsor
Eisai Limited
Industry
Eligibility
50 Years to 80 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Clermont, Florida • Lady Lake, Florida • District Heights, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Behavioral and Psychological Symptoms of Dementia: Family Caregivers (Aim 1)

NCT04481568
View directory record Official record
Conditions
Alzheimer's Disease and Related Dementias
Interventions
PES-4-BPSD Model, The attention control condition
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
65 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Glen Oaks, New York • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment

NCT00422981
View directory record Official record
Conditions
Mild Cognitive Impairment, So Stated
Interventions
AL-108, Placebo
Drug
Lead sponsor
Allon Therapeutics
Industry
Eligibility
55 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
17
States / cities
Peoria, Arizona • Garden Grove, California • National City, California + 13 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2012 · Synced Sep 25, 2026, 5:55 AM EDT
Recruiting Phase 3 Interventional

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

NCT07177352
View directory record Official record
Conditions
Alzheimers Disease
Interventions
No Intervention
Other
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
50 Years to 90 Years
Enrollment
80,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
68
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sun City, Arizona + 60 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 25, 2026, 5:55 AM EDT
Completed Phase 1 Interventional

Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia

NCT01640275
View directory record Official record
Conditions
General Anesthesia
Interventions
Propofol, Isoflurane
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Sep 25, 2026, 5:55 AM EDT