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ClinicalTrials.gov public records Last synced Oct 26, 2026, 10:10 AM EDT

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Showing 697–720 of 1,191 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Back Pain Clear all
Completed Not applicable Interventional Results available

Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain

NCT04009837
View directory record Official record
Conditions
Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
Interventions
Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
60 Years to 85 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Newark, Delaware • Durham, North Carolina • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

CAFE Study - Cancer Patient Fracture Evaluation

NCT00211237
View directory record Official record
Conditions
Cancer, Spinal Fractures
Interventions
Balloon Kyphoplasty, Non Surgical Management
Device · Other
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
9
States / cities
Escondido, California • Boulder, Colorado • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 26, 2026, 10:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain

NCT03709901
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Active Allograft, Placebo
Other
Lead sponsor
VIVEX Biologics, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
13
States / cities
Santa Monica, California • Walnut Creek, California • Tampa, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional

The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain

NCT04246281
View directory record Official record
Conditions
Low Back Pain, Back Pain
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System, Standard interventional management of low back pain
Device · Procedure
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
18
States / cities
Little Rock, Arkansas • Walnut Creek, California • Greenwood Village, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Repetitive Transcranial Magnetic Stimulation on Pain Thresholds in Patients With Chronic Low Back Pain

NCT03973788
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
repetitive transcranial magnetic stimulation (rTMS)
Procedure
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Feasibility and Efficacy of Remotely Monitored Home-based Listening to Preferred Music for Pain in Older Adults With Low Back Pain

NCT04644757
View directory record Official record
Conditions
Lower Back Pain
Interventions
Music Listening
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Oct 26, 2026, 10:10 AM EDT
Terminated Phase 4 Interventional

Comparison of Intraspinal Nerve Root Stimulation With Dorsal Column Stimulation

NCT00370773
View directory record Official record
Conditions
Back Pain
Interventions
Precision Spinal Cord Stimulation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Daphne, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 5, 2008 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Phase 2 Interventional

Psychosocial Treatment for Acute Low Back Pain

NCT00000418
View directory record Official record
Conditions
Acute Low Back Pain
Interventions
Psychosocial intervention
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1977 – 2001
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 6, 2013 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Phase 2 Interventional

Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain

NCT01290367
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Single Dose MPCs Injection, Single injection of saline solution, Single injection of hyaluronic acid
Biological · Procedure
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
13
States / cities
Scottsdale, Arizona • Sacramento, California • Santa Monica, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2020 · Synced Oct 26, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

Brown Adipose Tissue Activation by Spinal Cord Stimulation

NCT04326192
View directory record Official record
Conditions
Pain, Back, Obesity, Morbid, Type 2 Diabetes
Interventions
Research electrode
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Recruiting No phase listed Observational

The Prevalence of Directional Preference in the Lumbar Stenosis Population

NCT07007663
View directory record Official record
Conditions
Lumbar Stenosis
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
48 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lake Success, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Phase 3 Interventional Results available

A Phase 3 Study of Tanezumab for Chronic Low Back Pain

NCT02528253
View directory record Official record
Conditions
Low Back Pain
Interventions
Placebo to Week 16; tanezumab 5mg SC, Placebo to Week 16, tanezumab 10 mg SC, Tanezumab 5 mg SC, Tanezumab 10 mg SC, Tramadol PR oral
Biological
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
1,832 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
179
States / cities
Birmingham, Alabama • Mobile, Alabama • Saraland, Alabama + 124 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2020 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional

TENS for Back Pain Emergency Department

NCT04227067
View directory record Official record
Conditions
Back Pain
Interventions
TENS, SHAM TENS
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Oct 26, 2026, 10:10 AM EDT
Recruiting Early Phase 1 Interventional

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

NCT05461092
View directory record Official record
Conditions
Delirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane Block
Interventions
Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring, Generalized Anxiety Disorder 7-item (GAD-7) scale, Numerical Rating Score (NRS), PROMIS-Pain Interference, Oswestry Disability Index (ODI), Saint Louis University Mental Status Examination (SLUMs), Delirium Rating Scale-Revised-98 (DRS), Telephone Interview for Cognitive Status - Modified (TICS-M), Opioid Equivalents measured by Morphine Milligram Equivalents (MME), Patient Health Questionnaire depression scale (PHQ-8), Pain Catastrophizing, Fear Avoidance Beliefs Questionnaire (FABQ), Opioid Side Effects and Likeability Questionnaire, Daily Pain Trajectory, Tampa Scale of Kinesiophobia, Quality of Recovery 15
Drug · Diagnostic Test · Other
Lead sponsor
University of Iowa
Other
Eligibility
65 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Phase 4 Interventional Results available

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

NCT01502644
View directory record Official record
Conditions
Chronic Low Back Pain, Degenerative Disc Disease, Depression, Anxiety
Interventions
Oxycodone, Morphine, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 26, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.

NCT07130812
View directory record Official record
Conditions
Low Back Pain
Interventions
blood flow restriction, Heavy load resistance training
Other
Lead sponsor
Loma Linda University
Other
Eligibility
13 Years to 20 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain

NCT00899600
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Ketamine, Normal saline
Drug · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Oct 26, 2026, 10:10 AM EDT
Not listed Not applicable Interventional

A Prospective Study of Clinical Outcomes Following a Single Intradiscal Injection of Bone Marrow Aspirate Concentrate (BMAC) for Single Level Discogenic Low Back Pain

NCT03912454
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Degeneration
Interventions
Autologous Bone Marrow Aspirate Concentrate (BMAC) Injection
Other
Lead sponsor
Bone and Joint Clinic of Baton Rouge
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Oct 26, 2026, 10:10 AM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

NCT05052541
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
THC/CBD, THC, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 84 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2010 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional

Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain

NCT03597191
View directory record Official record
Conditions
Low Back Pain, Chronic Low Back Pain, Subacute Low Back Pain
Interventions
Exercises
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Phase 2 Interventional

Thrust Manipulation Versus Non-Thrust Manipulation

NCT01438203
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Thrust manipulation, Non-thrust manipulation
Procedure
Lead sponsor
Walsh University
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
North Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 5, 2012 · Synced Oct 26, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

Discogen for Low Back Pain

NCT06611397
View directory record Official record
Conditions
Disc Herniation
Interventions
Discogen Low pulsed ultrasound treatment, Discogen Sham Treatment
Device
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 26, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Restorative Exercise for Strength Training and Operational Resilience (RESTORE) for Chronic or Recurrent Low Back Pain

NCT02132910
View directory record Official record
Conditions
Lower Back Pain
Interventions
RESTORE Intervention
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 68 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 26, 2026, 10:10 AM EDT