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ClinicalTrials.gov public records Last synced Oct 19, 2026, 5:11 AM EDT

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Showing 1–24 of 913 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Brain Ischemia Clear all
Terminated Phase 4 Interventional

Rosuvastatin in African Americans With Cerebrovascular Disease

NCT01975194
View directory record Official record
Conditions
Stroke, Transient Ischemic Attack
Interventions
Rosuvastatin
Drug
Lead sponsor
Wayne State University
Other
Eligibility
30 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety Trial of Transcranial Laser Therapy Within 24 Hours From Stroke Onset (NEST-3)

NCT01120301
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
NeuroThera® Laser System
Device
Lead sponsor
PhotoThera, Inc
Industry
Eligibility
40 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
26
States / cities
Birmingham, Alabama • Fort Smith, Arkansas • Encinitas, California + 23 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2013 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury

NCT03496545
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Subdural Hematoma, Traumatic Brain Injury, Ischemic Stroke, Fever, Intracerebral Hemorrhage
Interventions
Bromocriptine 5 MG, Acetaminophen 650 MG
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 19, 2026, 5:11 AM EDT
Not listed Not applicable Interventional

Cryptogenic Stroke Study

NCT00861133
View directory record Official record
Conditions
Cryptogenic Stroke
Interventions
Sleuth AT Implantable ECG Monitoring System
Device
Lead sponsor
Transoma Medical
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 5, 2009 · Synced Oct 19, 2026, 5:11 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities

NCT03996317
View directory record Official record
Conditions
Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure, Meconium Aspiration Syndrome, Intracranial Hemorrhages, Neonatal Hypotension
Interventions
Room air
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Not applicable Interventional

Comparison of Lower vs Upper Extremity Injection Agitated Saline to Identify Patent Foramen Ovale With Echocardiography

NCT07009678
View directory record Official record
Conditions
Patent Foramen Ovale, Cryptogenic Stroke, Embolic Infarction
Interventions
intravenous access in greater saphenous vein compared to upper extremity site.
Diagnostic Test
Lead sponsor
St. John's Hospital
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Maple Grove, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology

NCT04141774
View directory record Official record
Conditions
Stroke
Interventions
Functional Electric Stimulation (FES), Behavioral Assessments, Magnetic Resonance Imaging, EEG
Device · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Not applicable Interventional

pRESET for Occlusive Stroke Treatment

NCT03994822
View directory record Official record
Conditions
Brain Diseases, Cardiovascular Diseases, Central Nervous System Diseases, Cerebrovascular Disorders, Ischemia, Nervous System Diseases, Pathologic Processes, Stroke, Ischemic, Stroke, Acute, Vascular Diseases
Interventions
Mechanical Thrombectomy using the pRESET Thrombectomy device, Mechanical Thrombectomy using the Solitaire Revascularization Device
Device
Lead sponsor
phenox Inc.
Industry
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
19
States / cities
Scottsdale, Arizona • Santa Monica, California • Coral Gables, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 19, 2026, 5:11 AM EDT
Not listed Not applicable Interventional

Stroke Recovery and Music or No Music

NCT03608904
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Music listening, Spoken word (language) listening
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 19, 2026, 5:11 AM EDT
Not yet recruiting No phase listed Observational

Stenting for Ischemic Strokes Secondary to Medically Refractory Intracranial Atherosclerotic Disease

NCT06790147
View directory record Official record
Conditions
ICAD - Intracranial Atherosclerotic Disease, Ischemic Stroke
Interventions
Not listed
Lead sponsor
Nitin Goyal
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Not applicable Interventional Results available

Nasal EPAP for Stroke Patients With Sleep Apnea: a Pilot Trial.

NCT01703663
View directory record Official record
Conditions
Ischemic Stroke, Obstructive Sleep Apnea
Interventions
EPAP
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Oct 19, 2026, 5:11 AM EDT
Completed No phase listed Observational

Markers of Atrial Fibrillation

NCT02734758
View directory record Official record
Conditions
Stroke, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Phase 4 Interventional Results available

Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke

NCT00924638
View directory record Official record
Conditions
Cryptogenic Symptomatic Transient Ischemic Attack, Cryptogenic Ischemic Stroke
Interventions
Reveal® XT Insertable Cardiac Monitor
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
40 Years and older
Enrollment
447 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
19
States / cities
Mountain View, California • Denver, Colorado • Chicago, Illinois + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2014 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Systolic Blood Pressure Intervention Trial

NCT01206062
View directory record Official record
Conditions
Hypertension
Interventions
Intensive control of SBP, Standard control of SBP
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
50 Years and older
Enrollment
9,361 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 19, 2026, 5:11 AM EDT
Active, not recruiting Not applicable Interventional

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

NCT05035823
View directory record Official record
Conditions
Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis, Muscular Dystrophies, Spinal Cord Injuries, Stroke, Lacunar, Stroke Brainstem, Cervical Spinal Cord Injury, Spinal Muscular Atrophy, Tetraplegic; Paralysis, Quadriplegia/Tetraplegia
Interventions
Motor Neuroprosthesis (MNP)
Device
Lead sponsor
Synchron Medical, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
3
States / cities
Buffalo, New York • New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 19, 2026, 5:11 AM EDT
Completed No phase listed Observational

Diabetes, Lipoproteins and Accelerated Vascular Disease

NCT00005479
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis, Carotid Artery Diseases, Diabetes Mellitus, Non-insulin Dependent, Diabetes Mellitus
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 75 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 28, 2015 · Synced Oct 19, 2026, 5:11 AM EDT
Completed No phase listed Observational

Intracranial Atherosclerosis and Depression After Coronary Artery Bypass Graft

NCT01838356
View directory record Official record
Conditions
Depression, Intracranial Atherosclerosis, Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
40 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
New Haven, Connecticut • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 19, 2026, 5:11 AM EDT
Completed No phase listed Observational

Acute Kidney Injury Genomics and Biomarkers in TAVR Study

NCT02791880
View directory record Official record
Conditions
Acute Kidney Injury, Renal Insufficiency, Chronic, Heart Failure, Myocardial Infarction, Arrhythmias, Cardiac, Stroke
Interventions
Transcatheter Aortic Valve Replacement
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
3
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Darbe Administration in Newborns Undergoing Cooling for Encephalopathy

NCT01471015
View directory record Official record
Conditions
Hypoxic Ischemic Encephalopathy
Interventions
Darbepoetin alfa, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
Up to 24 Hours
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
7
States / cities
Albuquerque, New Mexico • Nashville, Tennessee • Ogden, Utah + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 19, 2026, 5:11 AM EDT
Enrolling by invitation Not applicable Interventional

Endovascular Therapy for Large Core Patients With Uncertain Response to Thrombectomy

NCT06961487
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke, Acute
Interventions
EndovascularThrombectomy, Endovascular thrombectomy with any FDA-approved device
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 19, 2026, 5:11 AM EDT
Recruiting Not applicable Interventional

Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Ischemic Stroke Recovery (Pro00061930)

NCT06148285
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Hyperbaric Oxygen Therapy
Device
Lead sponsor
LCMC Health
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Phase 4 Interventional

Quality Improvement in Stroke Prevention (QUISP)

NCT00328640
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Optimal treatment
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2007 · Synced Oct 19, 2026, 5:11 AM EDT
Terminated Phase 2 Interventional Results available

Study Evaluating The Safety And Efficacy Of PF-03049423 In Subjects With Ischemic Stroke

NCT01208233
View directory record Official record
Conditions
Ischemic Stroke
Interventions
PF-03049423, Placebo
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 85 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
32
States / cities
Birmingham, Alabama • Deerfield Beach, Florida • Fort Lauderdale, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2016 · Synced Oct 19, 2026, 5:11 AM EDT
Completed Not applicable Interventional

Goal-directed CPR Using Cerebral Oximetry

NCT04924985
View directory record Official record
Conditions
Ischemia, Reperfusion Injury
Interventions
Non-Physiological Feedback CPR, Physiological Feedback CPR
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 19, 2026, 5:11 AM EDT