- Conditions
- Opioid-induced Constipation
- Interventions
- Naldemedine, Placebo
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 553 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 49
- States / cities
- Birmingham, Alabama • Homewood, Alabama • Goodyear, Arizona + 46 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 110
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Constipation, Chronic Idiopathic Constipation, CIC
- Interventions
- BLI400 Laxative, BLI400 Placebo
- Drug
- Lead sponsor
- Braintree Laboratories
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,020 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 51
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 43 more
- Conditions
- Chronic Constipation
- Interventions
- RM-131, Placebo
- Drug
- Lead sponsor
- Motus Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Chronic Constipation
- Interventions
- ATI-7505
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 214 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 20
- States / cities
- Anaheim, California • San Carlos, California • San Diego, California + 17 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Naldemedine, Placebo
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 547 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 37
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Fresno, California + 34 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Placebo, Naldemedine
- Drug
- Lead sponsor
- Shionogi
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 49
- States / cities
- Phoenix, Arizona • Sun Lakes, Arizona • Little Rock, Arkansas + 46 more
- Conditions
- Opioid-induced Constipation
- Interventions
- RDC-1036 (ALKS 37), Placebo
- Drug
- Lead sponsor
- Alkermes, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 11
- States / cities
- Sheffield, Alabama • Anaheim, California • Pasadena, California + 8 more
- Conditions
- Chronic Constipation
- Interventions
- Kiwifruit, Fiber, Prunes
- Dietary Supplement
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Chronic Constipation, Diabete Mellitus
- Interventions
- linaclotide or placebo
- Drug
- Lead sponsor
- Texas Tech University Health Sciences Center, El Paso
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2027
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- Constipation
- Interventions
- PEG 3350, PEG-3350 with electrolytes, Glycerin
- Drug
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 2 Years to 18 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 2
- States / cities
- Carmel, Indiana • Indianapolis, Indiana
- Conditions
- Advanced Illness Patients With Opioid Induced Constipation
- Interventions
- SC Methylnaltrexone, SC Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 1
- States / cities
- Tarrytown, New York
- Conditions
- Constipation
- Interventions
- MD-1100 Acetate
- Drug
- Lead sponsor
- Ironwood Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 14
- States / cities
- Huntsville, Alabama • North Little Rock, Arkansas • Boynton Beach, Florida + 11 more
- Conditions
- Opioid-induced Constipation
- Interventions
- Tegaserod
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Timeline
- 2006 – 2007
- U.S. locations
- 57
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 49 more
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- Vibrating capsule
- Device
- Lead sponsor
- Vibrant Ltd.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 349 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 8
- States / cities
- Foley, Alabama • Tucson, Arizona • Augusta, Georgia + 5 more
- Conditions
- Constipation
- Interventions
- Tegaserod
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 670 participants
- Timeline
- 2006 – 2007
- U.S. locations
- 59
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 52 more
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- Elobixibat 10 mg/day, Elobixibat 5 mg/day, Placebo
- Drug
- Lead sponsor
- Ferring Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 314 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 45
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 41 more
- Conditions
- Functional Constipation (FC)
- Interventions
- plecanatide, Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Constipation Chronic Idiopathic, Cystic Fibrosis
- Interventions
- Maralixibat 9.5 MG/ML [Livmarli]
- Drug
- Lead sponsor
- Children's Hospital Los Angeles
- Other
- Eligibility
- 1 Year to 18 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Chronic Constipation
- Interventions
- TD-5108
- Drug
- Lead sponsor
- Alfasigma S.p.A.
- Industry
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Constipation
- Interventions
- Survey
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- Lubiprostone, Placebo
- Drug
- Lead sponsor
- Anchen Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 808 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 79
- States / cities
- Dothan, Alabama • Huntsville, Alabama • Mobile, Alabama + 76 more
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- Plecanatide
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 3
- States / cities
- North Hollywood, California • Tamarac, Florida • Raleigh, North Carolina
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- Lubiprostone
- Drug
- Lead sponsor
- Texas Tech University Health Sciences Center, El Paso
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 37 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- SP-304 0.3 mg, SP-304 1.0 mg, SP-304 3.0 mg, SP-304 9.0 mg, Placebo
- Drug
- Lead sponsor
- Bausch Health Americas, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 14
- States / cities
- Mesa, Arizona • Tucson, Arizona • Anaheim, California + 11 more