- Conditions
- Chronic Heart Failure
- Interventions
- Neurostimulation + Medication Management (Standard of Care), Standard of Care (Control)
- Device · Drug
- Lead sponsor
- Jerry Estep, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2018
- U.S. locations
- 1
- States / cities
- Houston, Texas
Search Results
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Showing 1–24
of 363
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Chronic Heart Failure
- Interventions
- RLX030 (serelaxin), Placebo
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 321 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 9
- States / cities
- Anaheim, California • Colorado Springs, Colorado • Jacksonville, Florida + 5 more
- Conditions
- Heart Failure
- Interventions
- Ertugliflozin, Metolazone, Placebo
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Congestive Heart Failure, Diabetes, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease, Cancer, Cerebrovascular Disease, Alzheimer's Disease, Psychotic Disorder, Major Depression
- Interventions
- Care Coordination
- Behavioral
- Lead sponsor
- Mathematica Policy Research, Inc.
- Other
- Eligibility
- Not listed
- Enrollment
- 18,277 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2016
- U.S. locations
- 15
- States / cities
- Phoenix, Arizona • Washington D.C., District of Columbia • Sunrise, Florida + 12 more
- Conditions
- Heart Failure, Systolic
- Interventions
- Sacubitril/Valsartan
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 402 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Lower Extremity Edema, Congestive Heart Failure(CHF), Chronic Venous Insufficiency (CVI), Kidney Disease
- Interventions
- Pedal Pump, Pedal Pump Sham
- Device
- Lead sponsor
- David McVay
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Tulsa, Oklahoma
- Conditions
- Heart Failure
- Interventions
- Cenderitide
- Drug
- Lead sponsor
- Capricor Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Tustin, California
- Conditions
- Stem Cell Transplantation, Ventricular Dysfunction, Left
- Interventions
- Autologous human mesenchymal cells (hMSCs), Autologous human bone marrow cells (hBMCs), Placebo
- Biological
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 21 Years to 90 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Heart Failure, ADHF, Chronic Heart Failure, CHF
- Interventions
- Cenderitide, Placebo
- Drug · Other
- Lead sponsor
- Nile Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011
- U.S. locations
- 5
- States / cities
- Tustin, California • Jacksonville, Florida • Lenexa, Kansas + 2 more
- Conditions
- Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease, Hypertension, Hypertension (HTN), Hypertrophic Cardiomyopathy Patients, Hypertrophic Cardiomyopathy Without Obstruction, Hypertrophic Cardiomyopathy, Obstructive, Dilated Cardiomyopathy (DCM), Dilated Cardiomyopathy, Dilated Cardiomyopathy, Familial
- Interventions
- Not listed
- Lead sponsor
- Prolaio
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 5,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Heart Failure
- Interventions
- carvedilol
- Drug
- Lead sponsor
- Cardiovascular Clinical Sciences Inc
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 54
- States / cities
- Mobile, Alabama • Sierra Vista, Arizona • Anaheim, California + 49 more
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Arthritis, COPD, Depression
- Interventions
- Homing in on Health
- Behavioral
- Lead sponsor
- Agency for Healthcare Research and Quality (AHRQ)
- Federal
- Eligibility
- 40 Years and older
- Enrollment
- 415 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease, COPD Exacerbation, CHF, Congestive Heart Failure
- Interventions
- Data collection
- Other
- Lead sponsor
- Sensorum Health Inc.
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Neptune City, New Jersey
- Conditions
- Heart Failure
- Interventions
- Neladenoson bialanate (BAY1067197), Placebo
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 305 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 4
- States / cities
- Chicago, Illinois • St Louis, Missouri • Lincoln, Nebraska + 1 more
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Emphysema, Pulmonary Fibrosis, Interstitial Lung Disease
- Interventions
- ADAPT Intervention
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 306 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Seattle, Washington
- Conditions
- Chronic Kidney Diseases, Chronic Heart Failure, Iron Deficiency Anemia
- Interventions
- Iron Sucrose
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 251,831 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Congestive Heart Failure, Left Ventricular (LV) Systolic Dysfunction
- Interventions
- CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT)
- Device
- Lead sponsor
- CardioKinetix, Inc
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 331 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 67
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 53 more
- Conditions
- Heart Failure
- Interventions
- Medtronic PrimeADVANCED Neurostimulator
- Device
- Lead sponsor
- Medtronic Cardiac Rhythm and Heart Failure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 6
- States / cities
- Miami, Florida • Indianapolis, Indiana • Allentown, Pennsylvania + 3 more
- Conditions
- Heart Failure
- Interventions
- Empagliflozin, Placebo to Empagliflozin
- Drug
- Lead sponsor
- Boehringer Ingelheim
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 530 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 30
- States / cities
- Los Angeles, California • Orange, California • Torrance, California + 25 more
- Conditions
- Chronic Heart Failure
- Interventions
- conivaptan, placebo
- Drug
- Lead sponsor
- Cumberland Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2004
- U.S. locations
- 26
- States / cities
- Huntsville, Alabama • Los Angeles, California • Manteca, California + 22 more
- Conditions
- Heart Failure, Congestive Heart Failure, Chronic Heart Disease, CHF
- Interventions
- Optimizer Smart System
- Device
- Lead sponsor
- Impulse Dynamics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 106 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 17
- States / cities
- Mesa, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 10 more
- Conditions
- Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
- Interventions
- CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment
- Device
- Lead sponsor
- XSpline S.p.A.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 4
- States / cities
- Chicago, Illinois • Boston, Massachusetts • Durham, North Carolina
- Conditions
- Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Medtronic
- Industry
- Eligibility
- Not listed
- Enrollment
- 366 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2021
- U.S. locations
- 48
- States / cities
- Gilbert, Arizona • Little Rock, Arkansas • Rancho Mirage, California + 42 more