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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional

A Study to Evaluate the Efficacy, Safety, and Tolerability in Participants With Obesity or Overweight With Weight-Related Comorbidities

NCT07002905
View directory record Official record
Conditions
Chronic Weight Management
Interventions
ASC30 tablets or ASC30 tablets A1 or placebo
Drug
Lead sponsor
Ascletis Pharma (China) Co., Limited
Industry
Eligibility
18 Years to 75 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
6
States / cities
Rogers, Arkansas • Fort Myers, Florida • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Phase 3 Interventional Results available

A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program

NCT04657016
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Tirzepatide, Placebo
Drug · Other
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
579 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
45
States / cities
Huntington Park, California • Los Angeles, California • Montclair, California + 42 more
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Jun 26, 2026, 4:15 PM EDT
Completed No phase listed Observational

TODAY2 Phase 2 Follow-up

NCT02310724
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
TODAY cohort
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
15 Years and older
Enrollment
517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
15
States / cities
Los Angeles, California • Aurora, Colorado • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Jun 26, 2026, 4:15 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?

NCT06616363
View directory record Official record
Conditions
POTS - Postural Orthostatic Tachycardia Syndrome
Interventions
Questionnaires to be competed, Provide list of medication and lifetime events, Use phone App to record new life events, Will wear an activity monitor, Periodic 24-hour urine sodium check, A fMRI scan, A bedside tilt test will be performed, IV placed to collect blood samples, Stool Sample
Behavioral · Device · Other + 1 more
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 21 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Psychological Treatment of Overweight Binge Eaters

NCT01208272
View directory record Official record
Conditions
Binge Eating Disorder, Cognitive Therapy/Methods, Mental Disorders/Epidemiology, Obesity/Epidemiology, Obesity/Therapy
Interventions
Cognitive Behavioral Therapy (CBT), Interpersonal Therapy (IPT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 1999
U.S. locations
2
States / cities
New Haaven, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2010 · Synced Jun 26, 2026, 4:15 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetic Basis of Rosacea

NCT02787616
View directory record Official record
Conditions
Rosacea
Interventions
buccal swab
Genetic
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Improving Delivery of Mental Health Services for Patients With Drug Use and Other Behavioral and Emotional Problems

NCT00787735
View directory record Official record
Conditions
Study Focusing on Integrated Versus Non-integrated Psychiatric Care in, Opioid-dependent and Methadone Treated Patients With Other Psychiatric, Diagnoses
Interventions
Counseling compliance
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Jun 26, 2026, 4:15 PM EDT
Active, not recruiting Phase 2 Interventional

A Phase 2b, Dose-range Finding Study of the Efficacy and Safety of Multiple Doses of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity

NCT06693843
View directory record Official record
Conditions
Obesity, Overweight, or Chronic Weight Management
Interventions
Aleniglipron or Placebo, Aleniglipron
Drug
Lead sponsor
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Industry
Eligibility
18 Years to 79 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
39
States / cities
Phoenix, Arizona • Anaheim, California • Los Angeles, California + 33 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Withdrawn Not applicable Interventional

The Impact of Mindfulness Meditation in Veterans With Epilepsy

NCT03589755
View directory record Official record
Conditions
Epilepsy
Interventions
Mindfulness meditation
Behavioral
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Implementing, a Mobile Health Application for HIV Infected and Uninfected Women With Co-morbidities in the Outpatient Setting

NCT04810260
View directory record Official record
Conditions
Mobile Health, Asthma, Diabetes Mellitus
Interventions
Use mobile health app (WellXcel) to increase knowledge
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Jun 26, 2026, 4:15 PM EDT
Recruiting Phase 1 Interventional

A Study to Evaluate the Safety and Tolerability of Different Doses of CX11 Tablets

NCT07652047
View directory record Official record
Conditions
Obesity & Overweight
Interventions
CX11, Placebo
Drug · Other
Lead sponsor
Corxel Pharmaceuticals
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Las Vegas, Nevada • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Care Coordination to Assess Improvement in Outcomes in Hospital Readmissions

NCT04905160
View directory record Official record
Conditions
Heart Failure, ADHF, Acute MI
Interventions
COMPASSION Digital Biomarker
Other
Lead sponsor
Aventyn, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Alcohol & Metabolic Comorbidities in PLWHA: Evidence Driven Interventions

NCT03299205
View directory record Official record
Conditions
HIV/AIDS, Dysglycemia, Alcohol Use Disorder
Interventions
Exercise
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Jun 26, 2026, 4:15 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Congenital Heart Initiative-Redefining Outcomes and Navigation to Adult Centered Care

NCT05185232
View directory record Official record
Conditions
Congenital Heart Disease, Comorbidities and Coexisting Conditions
Interventions
Impact of gaps in care/loss to healthcare follow-up
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
16
States / cities
San Francisco, California • Aurora, Colorado • Washington D.C., District of Columbia + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project Wellness Enhancement: Increasing Health Care Choice and Outcomes for People With Mental Illness

NCT02263742
View directory record Official record
Conditions
Mental Health Wellness 1, Mental Illnesses, Other Diagnoses, Comorbidities, and Complications | Patient
Interventions
Peer whole health intervention, EBPs at Wellness Center
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Phase 2 Interventional

A Weight Loss Study Evaluating Subcutaneous Treatment With AZD9550 and AZD6234 in Combination Against Placebo or Each of the Drugs Alone

NCT06862791
View directory record Official record
Conditions
Obesity or Overweight
Interventions
AZD9550, AZD6234, Placebo comparator
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 75 Years
Enrollment
377 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
29
States / cities
Dothan, Alabama • Vestavia Hills, Alabama • Cerritos, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Completed No phase listed Observational

EMERALD - AssEssment of CoMorbidities & Atrial ArRhythmiA Burden in DuaL-Chamber PaceD Patients

NCT01188356
View directory record Official record
Conditions
Atrial Arrhythmia
Interventions
Not listed
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
4,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
32
States / cities
Mesa, Arizona • Peoria, Arizona • Phoenix, Arizona + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Not applicable Interventional

Research on Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders

NCT01117753
View directory record Official record
Conditions
Substance-Related Disorders, Depressive Disorder, Anxiety Disorder
Interventions
OutPatient Treatment for Adolescents (OPT-A), Treatment As Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
10 Years to 17 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Active, not recruiting Phase 2 Interventional

A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

NCT07281937
View directory record Official record
Conditions
Obesity, Overweight
Interventions
VRB-101, Placebo
Drug
Lead sponsor
Verdiva Bio Dev Limited
Industry
Eligibility
18 Years to 80 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
22
States / cities
Anniston, Alabama • Cullman, Alabama • Phoenix, Arizona + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Not yet recruiting Phase 3 Interventional

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

NCT07654361
View directory record Official record
Conditions
Obesity, Overweight, Chronic Weight Management
Interventions
Aleniglipron, Placebo
Drug
Lead sponsor
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Industry
Eligibility
18 Years to 79 Years
Enrollment
3,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
71
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sun City West, Arizona + 64 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Completed No phase listed Observational

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty

NCT02711709
View directory record Official record
Conditions
Sepsis
Interventions
Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics, Mobility Monitors
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Phase 1Phase 2 Interventional

Therapy for Depression With Co-occurring Panic or Anxiety Symptoms

NCT00051207
View directory record Official record
Conditions
Depression, Anxiety Disorders, Panic Disorder
Interventions
Interpersonal Psychotherapy (IPT), IPT for Depression with Co-occurring Panic and Anxiety Symptoms (IPT-PS)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2013 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pulse CO-Oximetry Noninvasive Monitoring and Laboratory Measurements of Subject Blood Samples

NCT01638455
View directory record Official record
Conditions
Various Comorbidities
Interventions
Noninvasive device
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
Not listed
Enrollment
2,776 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Jun 26, 2026, 4:15 PM EDT
Completed Phase 2 Interventional

Gemcitabine and Carboplatin Followed by Paclitaxel in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

NCT00276588
View directory record Official record
Conditions
Lung Cancer
Interventions
carboplatin, gemcitabine hydrochloride, paclitaxel
Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 8, 2010 · Synced Jun 26, 2026, 4:15 PM EDT