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ClinicalTrials.gov public records Last synced Oct 29, 2026, 1:30 PM EDT

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Showing 937–960 of 13,349 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Intracranial CNS Disorder Clear all
Completed Not applicable Interventional Results available

RELAXaHEAD for Headache Patients (Phase II)

NCT05466682
View directory record Official record
Conditions
Migraine, Headache, Multiple Sclerosis, Insomnia
Interventions
Smartphone-Based Progressive Muscle Relaxation Therapy (PMR), Monitored Usual Care (MUC)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Oct 29, 2026, 1:30 PM EDT
Recruiting Phase 2 Interventional

Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue

NCT05584124
View directory record Official record
Conditions
Stroke, Stroke, Chronic, Fatigue
Interventions
High frequency repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
34 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Decatur, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

Technology Intervention to Support Caregiving for Alzheimer's Disease (I-CARE)

NCT03119259
View directory record Official record
Conditions
Dementia, Alzheimer Type
Interventions
ABC Clinical Program, BCN
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 29, 2026, 1:30 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effectiveness of Alzheimer's Universe (Www.AlzU.Org) on Knowledge and Behavior

NCT03149380
View directory record Official record
Conditions
Alzheimer Disease, Alzheimer Disease, Late Onset, Memory Loss, Patient Education as Topic
Interventions
Web-based education
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
14 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 29, 2026, 1:30 PM EDT
Recruiting Not applicable Interventional

Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke

NCT05591196
View directory record Official record
Conditions
Stroke, Ischemic, Chronic Stroke
Interventions
Non-invasive Electrical Spinal Cord Stimulation, Activity Based Rehabilitation
Device · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

STAR Caregivers - Virtual Training and Follow-up

NCT04271046
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Caregiver Burnout
Interventions
STAR-C-VTF, Control
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
65 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 29, 2026, 1:30 PM EDT
Terminated Phase 1 Interventional Results available

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

NCT02255461
View directory record Official record
Conditions
Childhood Choroid Plexus Tumor, Childhood Ependymoblastoma, Childhood Grade III Meningioma, Childhood High-grade Cerebellar Astrocytoma, Childhood High-grade Cerebral Astrocytoma, Childhood Medulloepithelioma, Recurrent Childhood Anaplastic Astrocytoma, Recurrent Childhood Anaplastic Oligoastrocytoma, Recurrent Childhood Anaplastic Oligodendroglioma, Recurrent Childhood Brain Stem Glioma, Recurrent Childhood Cerebellar Astrocytoma, Recurrent Childhood Cerebral Astrocytoma, Recurrent Childhood Giant Cell Glioblastoma, Recurrent Childhood Glioblastoma, Recurrent Childhood Gliomatosis Cerebri, Recurrent Childhood Gliosarcoma, Recurrent Childhood Medulloblastoma, Recurrent Childhood Pineoblastoma, Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions
palbociclib isethionate, pharmacological study, laboratory biomarker analysis
Drug · Other
Lead sponsor
Pediatric Brain Tumor Consortium
Network
Eligibility
4 Years to 21 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
11
States / cities
Los Angeles, California • Palo Alto, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 29, 2026, 1:30 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Brain Stimulation to Improvement After Cerebellar Damage

NCT07838961
View directory record Official record
Conditions
Cerebellar Stroke, Autoimmune Cerebellar Disorders
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
George Wittenberg
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 29, 2026, 1:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the Risk of Stroke

NCT00417586
View directory record Official record
Conditions
Carotid Stenosis, Cerebrovascular Accident
Interventions
Specialized Doppler Ultrasound Instrument
Device
Lead sponsor
DVX, LLC
Industry
Eligibility
65 Years and older
Enrollment
984 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Phase 3 Interventional

The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme

NCT00076986
View directory record Official record
Conditions
Glioblastoma Multiforme
Interventions
IL13-PE38QQR, surgery and catheter placement (2 procedures), prolifespan 20 with carmustine implant (GLIADEL® Wafer), surgery and wafer placement (1 procedure)
Drug · Procedure
Lead sponsor
INSYS Therapeutics Inc
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
40
States / cities
Birmingham, Alabama • Duarte, California • Los Angeles, California + 30 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2011 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Phase 2 Interventional

Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD)

NCT00104273
View directory record Official record
Conditions
Dementia, Alzheimer's Disease
Interventions
Rasagiline
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
31
States / cities
Huntsville, Alabama • Tucson, Arizona • Little Rock, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2009 · Synced Oct 29, 2026, 1:30 PM EDT
Completed No phase listed Observational Results available

Follow Up Study for Treatment of Parkinson's Disease With Deep Brain Stimulation

NCT01022073
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 95 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
12
States / cities
Los Angeles, California • San Francisco, California • West Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2016 · Synced Oct 29, 2026, 1:30 PM EDT
Terminated Phase 2 Interventional Results available

Pilot Study of DFN-11 Injection in Medication Overuse Headache

NCT02583425
View directory record Official record
Conditions
Medication Overuse Headache
Interventions
DFN-11 Injection
Drug
Lead sponsor
Dr. Reddy's Laboratories Limited
Industry
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Oct 29, 2026, 1:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Activity During Birth for Prediction of Newborns at Risk for Brain Injury

NCT02445417
View directory record Official record
Conditions
Encephalopathy, Asphyxia Newborns
Interventions
Not listed
Lead sponsor
Sharp HealthCare
Other
Eligibility
36 Weeks to 44 Weeks
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2018 · Synced Oct 29, 2026, 1:30 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

A Single and Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of PU-AD in Healthy Subjects

NCT03935568
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
PU-AD, Placebo
Drug
Lead sponsor
Samus Therapeutics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 29, 2026, 1:30 PM EDT
Withdrawn Not applicable Interventional

Application of TMS Coupled With VR for Slowing the Rate of Cognitive Decline in Patients With Alzheimer's Disease

NCT04440891
View directory record Official record
Conditions
Alzheimer Disease
Interventions
TMS stimulation with X-Torp task, TMS-Stimulation with MindMotion Go, TMS-Sham with X-Torp task, TMS-Sham with MindMotion Go
Device
Lead sponsor
Ali Rezai
Other
Eligibility
50 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Phase 1 Interventional

Study to Evaluate the Safety, Tolerability and the Effect of BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects With Mild Alzheimer's Disease

NCT01492374
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
BMS-241027, Placebo matching BMS-241027
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
50 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
15
States / cities
Anaheim, California • Long Beach, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Phase 3 Interventional Results available

A Study To Evaluate The Safety And Efficacy Of IPX066 In Advanced Parkinson's Disease (ADVANCE-PD).

NCT00974974
View directory record Official record
Conditions
Parkinson's Disease
Interventions
IPX066, IR CD-LD
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
30 Years and older
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
35
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 30 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Oct 29, 2026, 1:30 PM EDT
Not yet recruiting Phase 2 Interventional

Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)

NCT07528690
View directory record Official record
Conditions
Hepatic Encephalopathy, Cirrhosis
Interventions
Microbiota transplant therapy (MTT) capsules, Placebo capsule
Biological · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
West Haven, Connecticut • Dallas, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy of Galantamine in Patients With Dementia With Lewy Bodies

NCT00230997
View directory record Official record
Conditions
Lewy Body Disease
Interventions
Galantamine
Drug
Lead sponsor
Neurological Research Center
Industry
Eligibility
51 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
5
States / cities
Indianapolis, Indiana • Buffalo, New York • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2005 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease

NCT04946760
View directory record Official record
Conditions
Parkinson Disease
Interventions
Sham Manipulation
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
50 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia)

NCT05697380
View directory record Official record
Conditions
Aphasia, Primary Progressive Aphasia, Dementia, Communication, Alzheimer Disease
Interventions
Communication Bridge™
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 29, 2026, 1:30 PM EDT
Completed Not applicable Interventional

Enhancing Written Communication in Persons With Aphasia

NCT01790880
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
ORLA, ORLA + Writing
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 29, 2026, 1:30 PM EDT
Not listed No phase listed Observational

Relationship Between Vestibular Function and Topographic Memory

NCT01780896
View directory record Official record
Conditions
Normal Elderly Population
Interventions
Not listed
Lead sponsor
Biomedical Development Corporation
Industry
Eligibility
70 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2013 · Synced Oct 29, 2026, 1:30 PM EDT