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ClinicalTrials.gov public records Last synced Oct 30, 2026, 3:34 AM EDT

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Showing 721–744 of 3,902 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adult Clear all
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) Compared With Egg-Based Quadrivalent Influenza Vaccine (IIV4) in Participants Aged 3 to 8 Years

NCT05513391
View directory record Official record
Conditions
Influenza Immunization
Interventions
Recombinant influenza vaccine (RIV4), Quadrivalent influenza vaccine (IIV4)
Biological
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
3 Years to 8 Years
Enrollment
366 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
18
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety Skills Training: Parents of School-Aged Children

NCT02329340
View directory record Official record
Conditions
Injuries
Interventions
Am Academy of Pediatrics print materials, Family safety 1-2-3
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 31, 2014 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training to Improve Physical Function in the Elderly

NCT01385475
View directory record Official record
Conditions
Physical Function
Interventions
RT
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
65 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 30, 2011 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional

A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures

NCT01589692
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Open Reduction and Internal Fixation, External Fixation, Percutaneous Pinning, Closed Reduction and casting
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
20
States / cities
Farmington, Connecticut • Louisville, Kentucky • Baltimore, Maryland + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 1 Interventional

Intervention for Anxiety After Falls

NCT01268657
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Specific Phobia, Anxiety
Interventions
Education, Relaxation Training, Cognitive Restructuring, Behavioral Activation, Exposure
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years to 105 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional Results available

Measuring Brain Amyloid Plaque Load in Older Adults Using BAY 94-9172

NCT01222351
View directory record Official record
Conditions
Late Onset Alzheimer Disease
Interventions
BAY 94-9172 (Florbetaben)
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
65 Years and older
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Immunogenicity & Safety of GSK's Influenza Vaccine 1557484A Given to Adults Aged ≥18 Years

NCT00616928
View directory record Official record
Conditions
Influenza
Interventions
Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted, Placebo
Biological
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
4,561 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
30
States / cities
Huntsville, Alabama • Phoenix, Arizona • Anaheim, California + 27 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2018 · Synced Oct 30, 2026, 3:34 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults

NCT07727577
View directory record Official record
Conditions
Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Colby-Sawyer College
Other
Eligibility
55 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New London, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional Results available

Increasing Physical Activity in Older Adults With Osteoarthritis Pain: Examining a Brief Behavioral Intervention

NCT04490395
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Engage PA, Treatment as Usual plus (TAU+)
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Buprenorphine Used With Treatment Resistant Depression in Older Adults

NCT02181231
View directory record Official record
Conditions
Major Depressive Disorder, Depression
Interventions
venlafaxine XR, buprenorphine, Placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 30, 2026, 3:34 AM EDT
Withdrawn Phase 1 Interventional

A Pharmacokinetic, Pharmacodynamic, Safety and Tolerability Study of CERC-006 in Adults With Complex Lymphatic Malformations

NCT04994002
View directory record Official record
Conditions
Lymphatic Malformation
Interventions
CERC-006
Drug
Lead sponsor
Avalo Therapeutics, Inc.
Industry
Eligibility
18 Years to 31 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Aurora, Colorado • Atlanta, Georgia • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA

NCT05562037
View directory record Official record
Conditions
Angina, Stable, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Interventions
Stepped Care
Other
Lead sponsor
Peter Lindenauer, MD
Other
Eligibility
60 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Pittsfield, Massachusetts • Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain

NCT05373745
View directory record Official record
Conditions
Chronic Pain, Mild Cognitive Impairment, Older Adults, Physical Activity
Interventions
Active Brains 1, Active Brains 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years

NCT04899336
View directory record Official record
Conditions
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
Interventions
ExPEC9V, Placebo
Biological · Other
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
60 Years and older
Enrollment
17,797 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
142
States / cities
Guntersville, Alabama • Phoenix, Arizona • Sun City West, Arizona + 100 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 30, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

NCT02703207
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA COPD Overlap Syndrome
Interventions
Positive airway pressure, NIPPV and /or oxygen
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of SHP465 in Adults Aged 18-55 Years With Attention-deficit/ Hyperactivity Disorder (ADHD)

NCT02604407
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD)
Interventions
SHP465 12.5mg capsules (one capsule daily), Placebo, SHP465 12.5mg, 25mg, or 37.5mg capsules (one capsule daily)
Drug · Other
Lead sponsor
Shire
Industry
Eligibility
18 Years to 55 Years
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
45
States / cities
Encino, California • Los Alamitos, California • Newport Beach, California + 40 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 30, 2026, 3:34 AM EDT
Completed No phase listed Observational

Parkinson's Genes and Environment Study

NCT00367900
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
50 Years and older
Enrollment
3,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2021 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Adjuvanted Seasonal Recombinant Quadrivalent Virus-Like Particles (QVLP) Influenza Vaccine in Adults 65 Years of Age and Older

NCT04622592
View directory record Official record
Conditions
Influenza
Interventions
Instramuscular vaccine
Biological
Lead sponsor
Medicago
Industry
Eligibility
65 Years and older
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
14
States / cities
Huntsville, Alabama • Chandler, Arizona • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Not applicable Interventional

BHS5 - Testing the Effectiveness of the Exercise Plus Program

NCT00389844
View directory record Official record
Conditions
Hip Fracture
Interventions
Exercise Trainer component of the Exercise Plus Program, Plus component (motivation) of the Exercise Plus Program, Exercise Plus Program (exercise + motivation)
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
65 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
5
States / cities
Baltimore, Maryland • Glen Burnie, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above

NCT07204964
View directory record Official record
Conditions
Influenza, Human
Interventions
Flu mRNA (Formulation B1), Flu mRNA (Formulation B3), Flu mRNA(Formulation A), Comparator 1, Comparator 2, Comparator 3
Biological · Combination Product
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
971 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
15
States / cities
Guntersville, Alabama • Canoga Park, California • Walnut Creek, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 30, 2026, 3:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Quantifying the Attentive Behaviors of Older Adults During Over-the-counter Drug Selection

NCT02188134
View directory record Official record
Conditions
Older Adults (65 Years and Older)
Interventions
Not listed
Lead sponsor
Michigan State University
Other
Eligibility
65 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 30, 2026, 3:34 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

NCT02565511
View directory record Official record
Conditions
Alzheimers Disease
Interventions
CAD106 Immunotherapy, Placebo to CAD106, CNP520, Placebo to CNP520, Alum
Biological · Other · Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
60 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
78
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Sun City, Arizona + 67 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 30, 2026, 3:34 AM EDT
Completed Phase 3 Interventional Results available

Safety Study of Entocort for Children With Crohn's Disease

NCT01444092
View directory record Official record
Conditions
Crohn's Disease
Interventions
Entocort
Drug
Lead sponsor
Padagis LLC
Industry
Eligibility
5 Years to 17 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
11
States / cities
Aurora, Colorado • Atlanta, Georgia • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2022 · Synced Oct 30, 2026, 3:34 AM EDT
Completed No phase listed Observational

EMPOWER-PULM (PULMonary Outcomes in Older Adults Empowered With Movement to Prevent Obesity and Weight Regain)

NCT03621098
View directory record Official record
Conditions
Obesity, Pulmonary Disease, Dyspnea
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 30, 2026, 3:34 AM EDT