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Showing 1–24 of 594 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Peripheral Artery Occlusion Clear all
Completed Not applicable Interventional Results available

Evaluating Plaque Photoablation Using an Excimer Laser in Patients With Lower Extremity Vascular Disease

NCT02653456
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
RA-308 Excimer Laser and DABRA Catheter
Device
Lead sponsor
Ra Medical Systems
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
El Centro, California • San Diego, California • Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Static Muscular Stretching for Treatment of PAD

NCT04222751
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Ankle Splint
Device
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 100 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 19, 2026, 10:08 PM EDT
Completed No phase listed Observational

Patient and Provider Assessment of Lipid Management Registry

NCT02341664
View directory record Official record
Conditions
Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes, Chronic Kidney Disease (CKD), Hypertension, Smoking, Myocardial Infarction (MI), Unstable Angina, Angina, Coronary Artery Disease (CAD), Stroke, Transient Ischemic Attack (TIA), Carotid Stenosis, Peripheral Arterial Disease, Atherosclerosis, Claudication
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
7,658 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
14
States / cities
Little Rock, Arkansas • San Pedro, California • Ventura, California + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

The DETOUR 2 Clinical Trial

NCT03119233
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
DETOUR System
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years to 90 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
30
States / cities
Scottsdale, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 27 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the GORE TIGRIS Vascular Stent

NCT01576055
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
TIGRIS Vascular Stent, BARD LifeStent
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
21 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
34
States / cities
Mobile, Alabama • Little Rock, Arkansas • Oceanside, California + 30 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Sep 19, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

NCT05811364
View directory record Official record
Conditions
Aortoiliac Occlusive Disease, Peripheral Arterial Disease
Interventions
Stenting of the Common and/or External Iliac Arteries with the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis, Stenting of the Common and/or External Iliac Arteries with Bare Metal Stent
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
26
States / cities
Little Rock, Arkansas • Long Beach, California • Denver, Colorado + 20 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 19, 2026, 10:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Functional MRI of the Lower Extremities

NCT03423316
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Supervised exercise therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 19, 2026, 10:08 PM EDT
Completed No phase listed Observational

Outcomes in Femoropopliteal Disease Stratified by Translesional Pressure Gradient

NCT02387658
View directory record Official record
Conditions
Peripheral Arterial Disease, Claudication
Interventions
translesional gradient measurement
Procedure
Lead sponsor
North Texas Veterans Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

Zilver® PTX® V Clinical Study

NCT01901289
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Zilver® PTX® Drug-Eluting Peripheral Stent
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
17
States / cities
Palo Alto, California • Stanford, California • Washington D.C., District of Columbia + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Activity To Improve Outcomes in Peripheral Arterial Disease

NCT02189018
View directory record Official record
Conditions
Peripheral Arterial Occlusive Disease
Interventions
Active Exercise, Neuromuscular electrical stimulation, Weight loss and active exercise, Ad lib activity at home
Other
Lead sponsor
Baltimore VA Medical Center
Federal
Eligibility
21 Years to 90 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Phase 2 Interventional

Zibotentan, an Endothelin Receptor Antagonist, Patients With Intermittent Claudication

NCT01890135
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Zibotentan (ZD4054), placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
40 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional

SoundBite™ Crossing System Pivotal Peripheral CTO Crossing Study

NCT03266835
View directory record Official record
Conditions
Chronic Total Occlusion of Arteries of the Extremities
Interventions
SoundBite™ Crossing System - Peripheral
Device
Lead sponsor
SoundBite Medical Solutions, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery

NCT01118117
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Misago™ Self-Expanding Stent System
Device
Lead sponsor
Terumo Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
31
States / cities
Birmingham, Alabama • Fairhope, Alabama • Little Rock, Arkansas + 27 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2017 · Synced Sep 19, 2026, 10:08 PM EDT
Terminated No phase listed Observational

Evaluating the Effects of EECP on Circulation, Blood Glucose Level and Blood Pressure in Type 2 Diabetes Mellitus

NCT02040025
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Not listed
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Drug Eluting Stent for the Management of PERipheral Arterial Disease Of the SFA (DESPERADO-SFA Study)

NCT02734836
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Balloon Angioplasty, Optical Coherence Tomography
Device · Other
Lead sponsor
Arkansas Heart Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Sep 19, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional

Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

NCT04228978
View directory record Official record
Conditions
Peripheral Artery Disease, Overweight or Obesity
Interventions
Weight loss, Exercise
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Chicago, Illinois • New Orleans, Louisiana • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Imaging of Peripheral Arteries by Optical Coherence Tomography and Intravascular Ultrasound Imaging

NCT03480685
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
IVUS and OCT Imaging
Device
Lead sponsor
Avinger, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
Hinsdale, Illinois • Pottstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Phase 2 Interventional Results available

Phase IIa: Safety, PK, & Tolerability of Sodium Nitrite in Patients With Peripheral Arterial Disease-SONIC

NCT01401517
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
sodium nitrite
Drug
Lead sponsor
TheraVasc Inc.
Industry
Eligibility
35 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
10
States / cities
Aurora, Colorado • Atlanta, Georgia • Iowa City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Phase 1 Interventional

Gene Expression and Tolerability Study of NV1FGF in Patients With Peripheral Artery Occlusive Disease Planned to Undergo Major Amputation

NCT01157143
View directory record Official record
Conditions
Peripheral Arterial Occlusive Disease
Interventions
XRP0038 (NV1FGF)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 4, 2010 · Synced Sep 19, 2026, 10:08 PM EDT
Recruiting Not applicable Interventional

BEETroot Juice to Reverse Functional Impairment in PAD

NCT05624125
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Beetroot juice, Placebo
Other
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
4
States / cities
Chicago, Illinois • Minneapolis, Minnesota • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Phase 2 Interventional

A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic Claudication

NCT01131013
View directory record Official record
Conditions
Intermittent Claudication, Peripheral Artery Disease
Interventions
Placebo, 375 mg CK-2017357, 500 mg CK-2017357
Drug
Lead sponsor
Cytokinetics
Industry
Eligibility
40 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
14
States / cities
Phoenix, Arizona • Santa Ana, California • Stanford, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Phase 2 Interventional Results available

Patients With Intermittent Claudication Injected With ALDH Bright Cells

NCT01774097
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
ALD-301, Placebo (vehicle)
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
40 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Stanford, California • Gainesville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 19, 2026, 10:08 PM EDT
Completed No phase listed Observational

Comparative Effectiveness Research Study of Peripheral Arterial Disease (PAD)

NCT01378260
View directory record Official record
Conditions
Peripheral Arterial Disease, Claudication
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
21 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
12
States / cities
Bellevue, Washington • Bellingham, Washington • Everett, Washington + 6 more
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Sep 19, 2026, 10:08 PM EDT
Completed Phase 4 Interventional

The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral Artery Disease

NCT05009862
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Rivaroxaban 2.5 Mg Oral Tablet, Placebo, Aspirin 81Mg Ec Tab
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 19, 2026, 10:08 PM EDT