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ClinicalTrials.gov public records Last synced Sep 28, 2026, 8:38 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Population at Risk Clear all
Terminated Phase 4 Interventional Results available

Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging

NCT02114697
View directory record Official record
Conditions
Atherosclerosis
Interventions
Statin therapy, Lifestyle modification
Drug · Behavioral
Lead sponsor
Emory University
Other
Eligibility
22 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Results available

Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)

NCT01897532
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Placebo, Linagliptin
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
6,991 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
197
States / cities
Huntsville, Alabama • Scottsboro, Alabama • Tuscumbia, Alabama + 150 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Sep 28, 2026, 8:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Aging With a Ketone Ester for Function in Frailty

NCT06645847
View directory record Official record
Conditions
Frail Elderly, Aging, Immune Function, Muscle Function
Interventions
Ketone ester, Placebo Comparator: Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Novato, California • Farmington, Connecticut • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 28, 2026, 8:38 AM EDT
Enrolling by invitation Not applicable Interventional

Centralized Lung Cancer Screening Engagement in At-Risk Populations

NCT07216144
View directory record Official record
Conditions
Lung Cancer Screening
Interventions
Centralized patient outreach for lung cancer screening
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years to 80 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Not applicable Interventional

A Video-Based HCV Curriculum for Active Injection Drug Users

NCT00241943
View directory record Official record
Conditions
Hepatitis C, Opiate Dependence
Interventions
Hepatitis C educational video
Procedure
Lead sponsor
Organization to Achieve Solutions in Substance Abuse (OASIS)
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2008 · Synced Sep 28, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County

NCT06387797
View directory record Official record
Conditions
At Risk for Type 2 Diabetes Mellitus, Pre Diabetes
Interventions
Cooking Matters for Adults (CMA)
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 28, 2026, 8:38 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia

NCT02569398
View directory record Official record
Conditions
Asymptomatic Amyloid-positive
Interventions
Atabecestat, 5 mg, Atabecestat, 25 mg, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
60 Years to 85 Years
Enrollment
557 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
64
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sun City, Arizona + 61 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Phase 3 Interventional

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

NCT01516541
View directory record Official record
Conditions
Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions
Background care, Placebo, dalcetrapib
Other · Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
45 Years and older
Enrollment
2,220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
121
States / cities
Birmingham, Alabama • Huntsville, Alabama • Anaheim, California + 112 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

SARS-COV-2 Screening in Dialysis Facilities

NCT05225298
View directory record Official record
Conditions
End-stage Renal Disease, SARS-CoV-2 Acute Respiratory Disease, Dialysis; Complications
Interventions
Offering SARS-CoV-2 test
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
2,389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Phase 3 Interventional

A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)

NCT06077864
View directory record Official record
Conditions
Obesity
Interventions
survodutide, Placebo
Combination Product
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
5,531 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
153
States / cities
Birmingham, Alabama • Daphne, Alabama • Mobile, Alabama + 135 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 28, 2026, 8:38 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

NCT03131453
View directory record Official record
Conditions
Alzheimers Disease
Interventions
CNP520 50mg, CNP520 15mg, Matching placebo
Drug · Other
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
60 Years to 75 Years
Enrollment
1,145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
95
States / cities
Phoenix, Arizona • Sun City, Arizona • Tucson, Arizona + 83 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Sep 28, 2026, 8:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

QuadraMune(TM) for Prevention of COVID-19

NCT04421391
View directory record Official record
Conditions
Covid19, Coronavirus, SARS-CoV 2
Interventions
QuadraMune(TM)
Dietary Supplement
Lead sponsor
Therapeutic Solutions International
Industry
Eligibility
18 Years to 120 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Oceanside, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 28, 2026, 8:38 AM EDT
Withdrawn Not applicable Interventional

Does Supplementing of Quadriceps Strength With Exoskeleton After Total Knee Arthroplasty in High Risk Population Reduce Transfer to Extended Care Facility (ECF)

NCT03762603
View directory record Official record
Conditions
Primary Knee Replacement Surgery
Interventions
Robotic exoskeleton device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 28, 2026, 8:38 AM EDT
Recruiting Not applicable Interventional

Telehealth Cognitive Behavioral Therapy for Youth at Risk for Psychosis

NCT05968560
View directory record Official record
Conditions
Clinical High Risk for Psychosis (CHR)
Interventions
CBT Skills Group for CHR Youth, Individual CBT sessions, CBT Skills Group for Families
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
14 Years to 25 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 28, 2026, 8:38 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

fFN Clinical Evaluation in Asymptomatic Women at High Risk for Preterm Birth

NCT01955148
View directory record Official record
Conditions
Pre-term Birth
Interventions
Not listed
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
1,210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
16
States / cities
Birmingham, Alabama • San Diego, California • Newark, Delaware + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2015 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HOPE (Harnessing Online Peer Education): Using Online Social Networks for HIV Prevention and Testing

NCT01701206
View directory record Official record
Conditions
HIV
Interventions
HIV knowledge Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
558 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Not applicable Interventional

Group-Based Lifestyle Intervention in Measuring Biomarker Levels in Participants at High Risk for Breast Cancer

NCT01874184
View directory record Official record
Conditions
Atypical Ductal Breast Hyperplasia, Atypical Lobular Breast Hyperplasia, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
Interventions
counseling intervention, behavioral dietary intervention, exercise intervention, questionnaire administration, laboratory biomarker analysis
Other · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
35 Years to 65 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 19, 2016 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digital Mental Health Care for COVID-19 High-Risk Populations

NCT04964570
View directory record Official record
Conditions
Stigma, Social, Help-Seeking Behavior
Interventions
Video _ behavioral change module
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 80 Years
Enrollment
4,134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Sep 28, 2026, 8:38 AM EDT
Completed No phase listed Observational

Comparison of Aneuploidy Risk Evaluations

NCT01663350
View directory record Official record
Conditions
Pregnancy, Down Syndrome, Edwards Syndrome, Patau Syndrome, Turners Syndrome
Interventions
Not listed
Lead sponsor
Verinata Health, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
26
States / cities
San Diego, California • Atlanta, Georgia • Chicago, Illinois + 22 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2013 · Synced Sep 28, 2026, 8:38 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Wisconsin Brain Donor Program

NCT00585572
View directory record Official record
Conditions
Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
9,999 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2050
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 28, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Strong Foundations 2.0: A Digitally Delivered Fall Prevention Program.

NCT05910606
View directory record Official record
Conditions
Fall Prevention, Bone Health, Balance
Interventions
Digital Exercise
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
60 Years to 99 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 28, 2026, 8:38 AM EDT
Completed No phase listed Observational

Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk Population

NCT03327870
View directory record Official record
Conditions
Sjogren's Syndrome, Oral Health
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Sep 28, 2026, 8:38 AM EDT
Completed Not applicable Interventional

Targeted Lifestyle Change Group Prenatal Care

NCT04090307
View directory record Official record
Conditions
Pregnancy, Gestational Diabetes
Interventions
TLC Group Prenatal Care
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years and older · Female only
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
St Louis, Missouri • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 28, 2026, 8:38 AM EDT