- Conditions
- Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury
- Interventions
- (MC-1) Pyridoxal 5'-phosphate
- Drug
- Lead sponsor
- Medicure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 3,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 63
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Ischemia/Reperfusion Injury After Neonatal Cardiac Surgery, Inflammatory Reaction After Neonatal Cardiac Surgery
- Interventions
- Inhaled Nitric Oxide, placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 1 Day to 30 Days
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Oak Lawn, Illinois
- Conditions
- Postoperative Hemorrhage
- Interventions
- Aprotinin (Trasylol, BAYA0128)
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 17
- States / cities
- Decatur, Alabama • Glendale, California • Pismo Beach, California + 13 more
- Conditions
- Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
- Interventions
- Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS), Sham LLVNS
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Vasoplegia
- Interventions
- Ascorbic Acid
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Cognitive Disorders, Delirium, Acute Kidney Injury
- Interventions
- Ketamine, Propofol
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 75 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Reperfusion Injury
- Interventions
- Ascorbic Acid, 5 % Dextrose Water or Normal Saline
- Drug · Other
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 1
- States / cities
- New Brunswick, New Jersey
- Conditions
- Cardiovascular Surgery, Pain, Postoperative, Block
- Interventions
- Liposomal bupivacaine, Normal Saline Flush, 0.9% Injectable Solution_#1
- Drug
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Preoperative Care, Surgery--Complications, Myocardial Infarction
- Interventions
- Not listed
- Lead sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 15,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 5
- States / cities
- Winston-Salem, North Carolina • Cleveland, Ohio • Houston, Texas
- Conditions
- Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
- Interventions
- DrugSorb-ATR system, Sham comparator
- Device
- Lead sponsor
- CytoSorbents, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 22
- States / cities
- Sacramento, California • New Haven, Connecticut • Washington D.C., District of Columbia + 18 more
- Conditions
- Delirium
- Interventions
- Dexmedetomidine, Propofol, Midazolam
- Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2004
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Glycemic Control, Surgical Site Infections, Cardiac Complications, Length of Stay, Cost
- Interventions
- standard insulin protocol post-op (continuous IV insulin)
- Drug
- Lead sponsor
- University of Vermont Medical Center
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 89 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Surgical Site Infection, Sternal Infection, Cardiac Surgery
- Interventions
- D-PLEX, Standard of Care
- Drug · Other
- Lead sponsor
- PolyPid Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 2
- States / cities
- Rochester, Minnesota • Huston, Texas
- Conditions
- Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
- Interventions
- Not listed
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Surgical Wound Infection, Cystitis, Bacteremia, Pneumonia, Enterocolitis, Pseudomembranous
- Interventions
- Synbiotic 2000
- Drug
- Lead sponsor
- Beth Israel Medical Center
- Other
- Eligibility
- Not listed
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Residual Neuromuscular Blockade
- Interventions
- Sugammadex, neostigmine/glycopyrolate
- Drug
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Vasoplegia, Hypotension, Coronary Artery Disease, Cardiac Valve Disease
- Interventions
- Hydroxocobalamin, Methylene Blue, Normal saline
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Ischemia-reperfusion Injury.
- Interventions
- Vardenafil
- Drug
- Lead sponsor
- McGuire Research Institute
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Coronary Artery Disease, Pain, Postoperative
- Interventions
- Exparel, Placebo
- Drug
- Lead sponsor
- Peter A Knight
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
- Interventions
- EEG Monitoring, Ropivacaine, Ketamine, Remifentanil, Dexmedetomidine, Rocuronium, Propofol
- Device · Drug
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Surgical Wound Infection
- Interventions
- TELFA™ A.M.D. Island dressing
- Device
- Lead sponsor
- Tyco Healthcare Group
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,100 participants
- Timeline
- 2004 – 2006
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Respiratory Failure, Respiratory Arrest, Respiratory Distress Syndrome, Acute Respiratory Failure, Acute Respiratory Failure With Hypoxia, Acute Respiratory Failure With Hypercapnia, Acute Respiratory Failure Post Surgical, Acute Respiratory Failure Postprocedural, Acute Respiratory Failure Following Trauma and Surgery, Acute Respiratory Failure Requiring Reintubation, Acute Respiratory Failure Post Traumatic, Acute Respiratory Decompensation, Shock, Shock, Septic, Shock, Cardiogenic, Acute Cardiac Failure, Multi Organ Failure, Acute Kidney Failure
- Interventions
- Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data
- Other
- Lead sponsor
- Efficacy Care R&D Ltd
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 50,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Atrial Fibrillation
- Interventions
- Ascorbic Acid, Identical Placebo
- Drug · Other
- Lead sponsor
- Regional Hospital of Scranton
- Other
- Eligibility
- 50 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Scranton, Pennsylvania
- Conditions
- Congenital Heart Defects
- Interventions
- CY-1503
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- Up to 45 Days
- Enrollment
- 242 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 2001
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts