- Conditions
- Flexion Contracture Following Total Knee Replacement
- Interventions
- Botox, placebo
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 2
- States / cities
- Bryn Mawr, Pennsylvania • Lankenau, Pennsylvania
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–48
of 368
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Arthroplasty, Replacement, Knee, Thromboembolism
- Interventions
- Dabigatran Dose 1 - day 2 to completion, Dabigatran Dose 1 - day 1, Dabigatran Dose 2 - day 2 to completion, Dabigatran Dose 2 - day 1, Enoxaparin
- Drug
- Lead sponsor
- Boehringer Ingelheim
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2,615 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2004
- U.S. locations
- 59
- States / cities
- Birmingham, Alabama • Northport, Alabama • Tucson, Arizona + 48 more
- Conditions
- Knee Arthroplasty
- Interventions
- Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System
- Procedure · Device
- Lead sponsor
- Northwest Surgical Specialists, Vancouver
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2023
- U.S. locations
- 1
- States / cities
- Vancouver, Washington
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism
- Interventions
- Enoxaparin + Placebo, Apixaban + Placebo
- Drug
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 3,608 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 25
- States / cities
- Birmingham, Alabama • Tuscaloosa, Alabama • Little Rock, Arkansas + 17 more
- Conditions
- Total Knee Replacement, Genicular Nerve Block, Opioid Use
- Interventions
- Bupivacaine Injection, Dexamethasone injection, Fentanyl, Mepivacaine
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Arthroplasty, Replacement, Knee, Total Knee Arthroplasty
- Interventions
- Lidocaine IV, Saline IV
- Drug
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Venous Thromboembolism, Bleeding
- Interventions
- Pharmacogenetic-based warfarin dosing, Usual care warfarin dosing
- Genetic · Other
- Lead sponsor
- Gwen McMillin
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 263 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Osteoarthritis
- Interventions
- AGG-523 (Aggrecanase Inhibitor)
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 5
- States / cities
- Boston, Massachusetts • Newton, Massachusetts • Winchester, Massachusetts + 1 more
- Conditions
- Knee Arthroplasty, Total
- Interventions
- ConforMIS custom total knee
- Device
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Surgery
- Interventions
- VR
- Behavioral
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Postoperative Recovery
- Interventions
- GRF6021, Placebo
- Biological · Other
- Lead sponsor
- Alkahest, Inc.
- Industry
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Total Knee Replacement
- Interventions
- Fondaparinux Sodium (Arixtra)
- Drug
- Lead sponsor
- Paul Di Cesare,MD
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Total Knee Arthroplasty
- Interventions
- Exercises plus walking program, Walking only program
- Other
- Lead sponsor
- Texas Woman's University
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA, Chronic Kidney Diseases, Diabetes, Autoimmune Diseases, Inflammatory Disease, Tobacco Use
- Interventions
- Cephalexin, Doxycycline, Cefadroxil
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 4,618 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2028
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Rochester, Minnesota
- Conditions
- Postoperative Pain, Knee Osteoarthritis
- Interventions
- Total knee replacement, COOLIEF
- Procedure · Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 65 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Inflammatory Arthritis
- Interventions
- Platelet Rich Plasma
- Biological
- Lead sponsor
- Exactech
- Industry
- Eligibility
- Not listed
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 2
- States / cities
- Lewiston, Maine • Salisbury, Maryland
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Comprehensive Behavioral Intervention, Standard of Care Exercise Program
- Behavioral · Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Total Knee Replacement Surgery
- Interventions
- Adductor Canal Catheter
- Device
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- San Leandro, California
- Conditions
- Total Knee Replacement, Postoperative Pain
- Interventions
- Bupivacaine HCl, F14 (celecoxib)
- Drug
- Lead sponsor
- Arthritis Innovation Corporation
- Industry
- Eligibility
- 45 Years to 80 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 3
- States / cities
- Denver, Colorado • Dayton, Ohio • San Antonio, Texas
- Conditions
- Arthritis of Knee
- Interventions
- Not listed
- Lead sponsor
- Athens Orthopedic Clinic, P.A.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 2
- States / cities
- Athens, Georgia
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- (Bupivacaine Liposome Injectable Suspension), Standard Preparation
- Drug
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Orange, California
- Conditions
- Osteoporosis, Arthroplasties, Knee Replacement
- Interventions
- Abaloparatide
- Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon® CR Total Knee System
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 419 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2017
- U.S. locations
- 11
- States / cities
- Phoenix, Arizona • Miami, Florida • Columbus, Georgia + 8 more