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ClinicalTrials.gov public records Last synced Oct 31, 2026, 7:53 AM EDT

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Showing 1–24 of 96 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ACP Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

S0000D: Effect of Vitamin E and/or Selenium on Colorectal Polyps in Men Enrolled on SELECT Trial SWOG-S0000

NCT00706121
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Condition
Interventions
Vitamin E, Selenium, Vitamin E placebo, selenium placebo
Drug
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
50 Years to 120 Years · Male only
Enrollment
8,094 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED)

NCT04931797
View directory record Official record
Conditions
Emergencies
Interventions
video decision aid, control arm ACP information sheet
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
598 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Davis, California • Boston, Massachusetts • Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 31, 2026, 7:53 AM EDT
Active, not recruiting Not applicable Interventional

Group Advanced Care Planning Pilot for Veterans

NCT06646614
View directory record Official record
Conditions
Cancer
Interventions
Group Advance Care Planning Education
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Preparing Spanish-speaking Older Adults for Advance Care Planning and Medical Decision Making (PREPARE)

NCT02072941
View directory record Official record
Conditions
Chronic Disease
Interventions
PREPARE Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years and older
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Oct 31, 2026, 7:53 AM EDT
Recruiting Not applicable Interventional

Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors

NCT07174661
View directory record Official record
Conditions
Advanced Malignant Solid Neoplasm, Malignant Brain Neoplasm, Recurrent Advanced Malignant Solid Neoplasm
Interventions
Advance Care Planning, Educational Intervention, Electronic Health Record Review, Survey Administration
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Phase 2 Interventional Results available

ACP-01 in Patients With Critical Limb Ischemia

NCT02551679
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
ACP-01, Placebo
Biological
Lead sponsor
Hemostemix
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
16
States / cities
Sacramento, California • Aurora, Colorado • Gainesville, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Longitudinal Pediatric Palliative Care: Quality of Life & Spiritual Struggle

NCT01289444
View directory record Official record
Conditions
HIV
Interventions
FAmily CEntered (FACE) ACP, Healthy Living Control
Behavioral
Lead sponsor
Maureen Lyon
Other
Eligibility
14 Years to 21 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Fort Lauderdale, Florida • Miami, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 31, 2026, 7:53 AM EDT
Active, not recruiting Phase 3 Interventional Results available

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

NCT04988295
View directory record Official record
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
Lazertinib, Amivantamab, Pemetrexed, Carboplatin
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years and older
Enrollment
776 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
28
States / cities
Mobile, Alabama • Tucson, Arizona • Duarte, California + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Disseminating a Digital ACP Platform (Our Care Wishes) to Hospitalized Patients

NCT03727685
View directory record Official record
Conditions
Hospitalism
Interventions
Our Care Wishes
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
16,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

AMPLATZER Cardiac Plug Clinical Trial

NCT01118299
View directory record Official record
Conditions
Atrial Fibrillation, Ischemic Stroke, Peripheral Thromboembolism
Interventions
AMPLATZER Cardiac Plug
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
18
States / cities
Los Angeles, California • Aurora, Colorado • Littleton, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Results available

Integrated Multidisciplinary Patient and Family Advance Care Planning Trial

NCT03609658
View directory record Official record
Conditions
Advance Care Planning
Interventions
Nurse Navigator Pathway, Usual Care
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
9
States / cities
Asheboro, North Carolina • Claremont, North Carolina • Conover, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 31, 2026, 7:53 AM EDT
Terminated Not applicable Interventional Results available

Integrating Conservative Kidney Management Options and Advance Care Planning Into a Pre-Dialysis Educational Program

NCT03229811
View directory record Official record
Conditions
Advance Care Planning, Chronic Kidney Diseases, Conservative Kidney Management
Interventions
ESRD education + conservative kidney management and ACP education
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2025 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy Study of Diabetes Group Visits

NCT01497301
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Group Visits
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 31, 2026, 7:53 AM EDT
Terminated Phase 3 Interventional

Consumer Engagement to Increase Advance Care Planning

NCT02208947
View directory record Official record
Conditions
Advance Care Planning
Interventions
Consumer financial incentive, PREPARE
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fairfield, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Videos for Advance Care Planning in Young Adults

NCT04149704
View directory record Official record
Conditions
Advanced Cancer
Interventions
ACP video decision aid, Usual Care-
Behavioral · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Preparing Family Caregivers to Make Medical Decisions for Their Loved Ones

NCT02429479
View directory record Official record
Conditions
Neoplasms, Heart Failure, Kidney Diseases, Lung Diseases
Interventions
Making Your Wishes Known, Standard advance care planning
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2024 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Phase 3 Interventional Results available

A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

NCT04435366
View directory record Official record
Conditions
Geographic Atrophy, Macular Degeneration
Interventions
Avacincaptad Pegol, Sham
Drug
Lead sponsor
IVERIC bio, Inc.
Industry
Eligibility
50 Years and older
Enrollment
448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
96
States / cities
Beverly Hills, California • Campbell, California • Fresno, California + 86 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 31, 2026, 7:53 AM EDT
Active, not recruiting Not applicable Interventional

ACP Video Intervention for Patients With Life-Limiting Illness

NCT04778761
View directory record Official record
Conditions
Health Care Utilization, End Stage Disease
Interventions
Home ACP Video
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Jersey City, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 31, 2026, 7:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Advance Care Planning: Communicating With Outpatients for Vital Informed Decision

NCT04660422
View directory record Official record
Conditions
Advanced Care Planning, Shared Decision Making, Video Decision Aids, Communication Skills, Advance Directives, Natural Language Processing, Covid19
Interventions
VitalTalk communication skills training, ACP Decisions Video Program, Intervention training:, Medical Record Review
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
65 Years and older
Enrollment
42,019 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sharing and Talking About my Preferences

NCT03103828
View directory record Official record
Conditions
Chronic Disease
Interventions
Computer-Tailored Intervention, Motivational Interviewing, Motivational Enhancement Therapy
Behavioral
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
55 Years and older
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Reducing Disparities in the Quality of Advance Care Planning for Older Adults

NCT03516994
View directory record Official record
Conditions
Metastatic Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Parkinson Disease, Interstitial Lung Disease, Amyotrophic Lateral Sclerosis, End Stage Liver Disease, End Stage Renal Disease, Diabetes Complications
Interventions
Respecting Choices First Steps, Five Wishes Form
Behavioral
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
790 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Birmingham, Alabama • Atlanta, Georgia • Columbia, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study

NCT02424097
View directory record Official record
Conditions
Dental White Spots, Dental Caries
Interventions
CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste, 1,100pm F-toothpaste and 0.5%NaF rinse
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
11 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 31, 2026, 7:53 AM EDT
Completed Not applicable Interventional

Advance Care Planning (ACP) in Primary Care for Dementia

NCT05322317
View directory record Official record
Conditions
Dementia, Advance Care Planning
Interventions
ADVANCE-PC training via ECHO
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 105 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 18, 2022 · Synced Oct 31, 2026, 7:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health

NCT01890889
View directory record Official record
Conditions
Cholesterol, Hyperlipidemia, Hypercholesteremia
Interventions
Ad-Chol-Pre, Half-dose Ad-Chol-Pre, Defatted egg yolk without the active ingredient of the other two interventions
Dietary Supplement · Other
Lead sponsor
Integrative Health Technologies, Inc.
Network
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 31, 2026, 7:53 AM EDT