- Conditions
- Carcinoma, Hepatocellular, Liver Cancer, Liver Cirrhosis, Hepatitis B
- Interventions
- GALAD, Liver Ultrasound with or without AFP
- Diagnostic Test
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 5,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2034
- U.S. locations
- 19
- States / cities
- Los Angeles, California • Redwood City, California • Roseville, California + 14 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 32
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Anal Fistula, Crohn's Disease
- Interventions
- Surgisis Biodesign Anal Fistula Plug (SurgiSIS AFP)
- Device
- Lead sponsor
- Cook Group Incorporated
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 3
- States / cities
- Los Angeles, California • New York, New York • Cleveland, Ohio
- Conditions
- Adult Primary Liver Cancer, Hepatitis C Infection
- Interventions
- S-adenosyl-L-methionine disulfate p-toluene-sulfonate, placebo, laboratory biomarker analysis, immunoenzyme technique, high performance liquid chromatography
- Drug · Other
- Lead sponsor
- Chao Family Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 5
- States / cities
- Tucson, Arizona • Long Beach, California • Los Angeles, California + 2 more
- Conditions
- Fistula in Ano, Crohn Disease
- Interventions
- MSC-AFP
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 12 Years to 17 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- PROM
- Interventions
- Use of Rapid Immunoassay Tests for the Detection of PROM
- Device
- Lead sponsor
- Clinical Innovations, LLC
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 324 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 3
- States / cities
- Newark, Delaware • Camden, New Jersey • Salt Lake City, Utah
- Conditions
- Anal Fistula
- Interventions
- Ligation of intersphincteric fistula track procedure, anal fistula plug
- Procedure
- Lead sponsor
- Colon and Rectal Surgery Associates, Ltd.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 124 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2009
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • Minneapolis, Minnesota • Philadelphia, Pennsylvania
- Conditions
- Carcinoma, Hepatocellular, Cirrhosis
- Interventions
- Abbreviated Magnetic Resonance Imaging with serum AFP, Abdominal Ultrasound Screening with serum AFP
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 4,700 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2031
- U.S. locations
- 34
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 31 more
- Conditions
- Hepatocellular Carcinoma
- Interventions
- Atezolizumab, Bevacizumab, Y^90 Radioembolization
- Drug · Radiation
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Hepatocellular Carcinoma
- Interventions
- Ramucirumab, Placebo
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 399 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 8
- States / cities
- Daly City, California • Los Angeles, California • Washington D.C., District of Columbia + 5 more
- Conditions
- Down Syndrome, Chromosome Abnormalities
- Interventions
- Ultrasound, Serum screen
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 16 Years to 45 Years · Female only
- Enrollment
- 38,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- U.S. locations
- 10
- States / cities
- Denver, Colorado • Boston, Massachusetts • Royal Oak, Michigan + 6 more
- Conditions
- Liver Cancer
- Interventions
- AFP
- Biological
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2008
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Liver Cancer
- Interventions
- AFP gene hepatocellular carcinoma vaccine
- Biological
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2002
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Perianal Fistula
- Interventions
- Only 1 arm: treatment with MSC-AFP
- Drug
- Lead sponsor
- William A. Faubion, M.D.
- Other
- Eligibility
- 12 Years to 17 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Thrombosis, Deep Vein, Iliofemoral; Thrombosis
- Interventions
- Perivascular dexamethasone, Perivascular sham
- Combination Product
- Lead sponsor
- Mercator MedSystems, Inc.
- Industry
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2028
- U.S. locations
- 15
- States / cities
- Orange, California • Darien, Connecticut • Atlantis, Florida + 12 more
- Conditions
- Hepatic Cancer
- Interventions
- Seravue
- Diagnostic Test
- Lead sponsor
- ImCare Biotech
- Industry
- Eligibility
- 21 Years to 84 Years
- Enrollment
- 1,392 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Metastatic Hepatocellular Carcinoma, Local Advanced Hepatocellular Carcinoma, Alpha-fetoprotein (AFP)-Producing Gastric Cancer, Extragonadal Yolk Sac Tumors, Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
- Interventions
- BGB-B2033, Tislelizumab, Bevacizumab
- Drug
- Lead sponsor
- BeOne Medicines
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 392 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 7
- States / cities
- Goodyear, Arizona • Duarte, California • Zion, Illinois + 4 more
- Conditions
- Hepatocellular Cancer, AFP Expressing Tumors
- Interventions
- Autologous genetically modified AFPᶜ³³²T cells
- Genetic
- Lead sponsor
- Adaptimmune
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2025
- U.S. locations
- 12
- States / cities
- Phoenix, Arizona • Los Angeles, California • Miami, Florida + 7 more
- Conditions
- Carcinoma, Hepatocellular, Liver Neoplasms
- Interventions
- Outreach with patient education and patient navigation services
- Behavioral
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 2,871 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Perianal Fistula, Cryptoglandular Perianal Fistula
- Interventions
- MSC-AFP
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Fistula Vagina, Crohn Disease
- Interventions
- MSC-AFP
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Attenuated Familial Adenomatous Polyposis, Deleterious Familial Adenomatous Polyposis
- Interventions
- Chart Review
- Other
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- Not listed
- Enrollment
- 1,500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2022
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Hepatocellular Carcinoma, Hepatoma, Liver Cancer, Adult, Liver Cell Carcinoma, Liver Cell Carcinoma, Adult, Cancer of Liver, Cancer of the Liver, Cancer, Hepatocellular, Hepatic Cancer, Hepatic Neoplasms, Hepatocellular Cancer, Liver Cancer, Neoplasms, Hepatic, Neoplasms, Liver
- Interventions
- AFP + GM-CSF Plasmid Prime and AFP Adenoviral Vector Boost
- Drug
- Lead sponsor
- Lisa H. Butterfield, Ph.D.
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Pittsburgh, Pennsylvania
- Conditions
- Hepatocellular Carcinoma, Cirrhosis, Liver, Hepatitis B
- Interventions
- Ultrasound or abbreviated MRI
- Diagnostic Test
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Tahlequah, Oklahoma
- Conditions
- Cirrhosis, End Stage Liver Disease, Hepatitis C
- Interventions
- Screening
- Procedure
- Lead sponsor
- Minneapolis Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2021
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota