- Conditions
- Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
- Interventions
- Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
- Other · Drug
- Lead sponsor
- University Health Network, Toronto
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6,250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 26
- States / cities
- Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
Search Results
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Showing 1–10
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- Conditions
- Respiratory Distress Syndrome
- Interventions
- spontaneous breathing trial
- Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 48 Hours to 14 Weeks
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 2
- States / cities
- Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania
- Conditions
- Morbid Obesity
- Interventions
- Esophageal Balloon, Cstat
- Device · Other
- Lead sponsor
- East Carolina University
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Greenville, North Carolina
- Conditions
- Acute Hypoxemic Respiratory Failure, Obesity
- Interventions
- PEEP Titration Using Electrical Impedance Tomography (EIT), Body Positioning: Supine and Prone
- Other · Procedure
- Lead sponsor
- Maurizio F. Cereda, MD
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2028 – 2030
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Healthy Adult Volunteers
- Interventions
- HFNC, CPAP
- Device
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Lung Injury, Preterm Birth
- Interventions
- Positive End-Expiratory Pressure (PEEP)
- Procedure
- Lead sponsor
- Murdoch Childrens Research Institute
- Other
- Eligibility
- 23 Weeks to 28 Weeks
- Enrollment
- 906 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2028
- U.S. locations
- 4
- States / cities
- Little Rock, Arkansas • San Diego, California • Indianapolis, Indiana + 1 more
- Conditions
- Spinal Cord Injuries
- Interventions
- High tidal volume, Low tidal volume
- Device
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 2
- States / cities
- Englewood, Colorado • Houston, Texas
- Conditions
- Status Asthmaticus
- Interventions
- NPPV plus standard of care
- Other
- Lead sponsor
- Southern Illinois University
- Other
- Eligibility
- 1 Year to 18 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Springfield, Illinois
- Conditions
- Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
- Interventions
- Application of positive-end-expiratory pressure
- Other
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 3 Months to 18 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- New Hyde Park, New York
- Conditions
- Acute Respiratory Distress Syndrome, Respiratory Failure
- Interventions
- Precision ventilation, Guided usual care ventilation
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 33
- States / cities
- Tucson, Arizona • Little Rock, Arkansas • La Jolla, California + 25 more