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ClinicalTrials.gov public records Last synced Oct 9, 2026, 5:50 AM EDT

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Showing 49–72 of 202 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Implantable Cardioverter Defibrillator (ICD) Clear all
Completed Not applicable Interventional

EnSite NavX-Guided Coronary Sinus Mapping During CRT Implant

NCT01615835
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
EnSite NavX System
Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
2
States / cities
Augusta, Georgia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 9, 2026, 5:50 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety Evaluation of Azimilide Dihydrochloride in Patients With Implantable Cardioverter Defibrillators

NCT00035490
View directory record Official record
Conditions
Arrhythmia
Interventions
Azimilide Dihydrochloride, placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
633 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
78
States / cities
Mobile, Alabama • Mesa, Arizona • Little Rock, Arkansas + 67 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2011 · Synced Oct 9, 2026, 5:50 AM EDT
Completed No phase listed Observational

Precision Event Monitoring for Patients With Heart Failure Using HeartLogic

NCT03579641
View directory record Official record
Conditions
Heart Failure, Defibrillators, Implantable, Monitoring, Physiologic, Cardiac Resynchronization Therapy, Cardiovascular Disease, Heart Disease
Interventions
HeartLogic Sensors
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
56
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 9, 2026, 5:50 AM EDT
Withdrawn Not applicable Interventional

Effect of Right Ventricular Lead Position on Defibrillation Threshold

NCT02844127
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation
Interventions
Implantable Cardioverter Defibrillator (ICD)
Procedure
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Oct 9, 2026, 5:50 AM EDT
Completed Not applicable Interventional

D2-EPG Study: Evaluation of New Sensing Circuitry and Capture Management

NCT00328705
View directory record Official record
Conditions
Heart Diseases
Interventions
Implantable Cardioverter Defibrillator
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
Tampa, Florida • Coon Rapids, Minnesota • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2008 · Synced Oct 9, 2026, 5:50 AM EDT
Terminated Phase 1 Interventional

A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT)

NCT05532046
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
BAY2413555 Dose 1, BAY2413555 Dose 2, Placebo to BAY2413555
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 79 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Atlanta, Georgia • Silver Spring, Maryland • Camp Hill, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 9, 2026, 5:50 AM EDT
Recruiting No phase listed Observational

Pacemaker and Defibrillator Lead Extraction Registry

NCT03847025
View directory record Official record
Conditions
Lead Extraction Procedures
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 9, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers

NCT04994782
View directory record Official record
Conditions
Implantable Defibrillator User, Terminal Illness
Interventions
GAME-EOL
Behavioral
Lead sponsor
Debra Moser
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 9, 2026, 5:50 AM EDT
Recruiting No phase listed Observational

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

NCT00271180
View directory record Official record
Conditions
Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
Interventions
Device
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1983 – 2040
U.S. locations
113
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 110 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 9, 2026, 5:50 AM EDT
Terminated Not applicable Interventional Results available

DEfibrillators To REduce Risk by MagnetIc ResoNance Imaging Evaluation

NCT00487279
View directory record Official record
Conditions
Coronary Artery Disease, Left Ventricular Dysfunction, Sudden Cardiac Death
Interventions
Defibrillator, Control
Device · Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
56
States / cities
Anchorage, Alaska • Tucson, Arizona • Glendale, California + 42 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 9, 2026, 5:50 AM EDT
Completed No phase listed Observational

Ventricular Tachyarrhythmia (VT) Storm, Gene Expression in Implantable Cardioverter Defibrillator (ICD) Patients With Electrical Storm

NCT00284453
View directory record Official record
Conditions
Arrhythmias
Interventions
Peripheral blood sampling
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2019 · Synced Oct 9, 2026, 5:50 AM EDT
Completed No phase listed Observational

Implantable Cardiac Defibrillators for the Prevention of Sudden Death in Patients With Cardiac Sarcoidosis

NCT01013311
View directory record Official record
Conditions
Sarcoidosis of the Heart, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 9, 2026, 5:50 AM EDT
Terminated No phase listed Observational

Study of Paced QRS Duration as a Marker of Sudden Cardiac Death

NCT01948206
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Not listed
Lead sponsor
Pocono Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
East Stroudsburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 13, 2016 · Synced Oct 9, 2026, 5:50 AM EDT
Terminated Not applicable Interventional Results available

ST Monitoring to Detect Acute Coronary Syndrome Events in Implantable Cardioverter Defibrillator Patients

NCT01424722
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Fortify® ST, Fortify Assura® ST, Ellipse® ST family of devices
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
97
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mesa, Arizona + 85 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Oct 9, 2026, 5:50 AM EDT
Recruiting Phase 4 Interventional

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

NCT06964464
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction (HFrEF), Sudden Cardiac Death, Ventricular Arrhythmia, Implantable Cardioverter Defibrillator (ICD), Beta-blocker Therapy, Cardiomyopathy
Interventions
Metoprolol Succinate, Carvedilol
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
13
States / cities
Scottsdale, Arizona • Rome, Georgia • Shawnee Mission, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 9, 2026, 5:50 AM EDT
Not listed No phase listed Observational

Does Lung Impedance Correlate With Changes in BNP in Stable and Acutely Decompensated Heart Failure Patients?

NCT00560339
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Southern New Jersey Cardiac Specialists
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
6
States / cities
Glendale, California • Voorhees Township, New Jersey • Roslyn, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2007 · Synced Oct 9, 2026, 5:50 AM EDT
Not listed No phase listed Observational

Gut Microbiome and Ventricular Arrhythmias

NCT04466072
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Gut Microbiome
Interventions
Stool test for microbial analysis
Diagnostic Test
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Oct 9, 2026, 5:50 AM EDT
Not listed No phase listed Observational

SCD-HeFT 10 Year Follow-up

NCT01058837
View directory record Official record
Conditions
Left Ventricular Systolic Dysfunction, Congestive Heart Failure, Ischemic and Non-ischemic Cardiomyopathy, Sudden Cardiac Death Primary Prevention
Interventions
Not listed
Lead sponsor
Seattle Institute for Cardiac Research
Other
Eligibility
18 Years to 90 Years
Enrollment
1,855 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Feb 11, 2010 · Synced Oct 9, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Left vs Left Randomized Clinical Trial

NCT05650658
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB, RBBB, Intraventricular Conduction Delay, Pacing-Induced Cardiomyopathy
Interventions
His/LBBP, BiVP
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
2,136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
57
States / cities
Gilbert, Arizona • Tucson, Arizona • Little Rock, Arkansas + 46 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 9, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Safety and Clinical Performance of the Protecta ICD and CRT-D

NCT00982397
View directory record Official record
Conditions
Tachyarrhythmias, Heart Failure, Ventricular Dysfunction
Interventions
Protecta VR-ICD, Protecta DR-ICD or CRT-D
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
2,770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
29
States / cities
Birmingham, Alabama • Mesa, Arizona • Fort Smith, Arkansas + 26 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 9, 2026, 5:50 AM EDT
Completed No phase listed Observational

Safety of Sports for Patients With Implantable Cardioverter-Defibrillators

NCT00637754
View directory record Official record
Conditions
Heart Arrhythmias
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
10 Years to 60 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
31
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2015 · Synced Oct 9, 2026, 5:50 AM EDT
Completed Phase 4 Interventional Results available

OptiVol® Care Pathway

NCT00847288
View directory record Official record
Conditions
Heart Failure
Interventions
Monthly Review Arm, Quarterly Review Arm
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
108
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 105 more
Source: ClinicalTrials.gov public record
Updated May 3, 2013 · Synced Oct 9, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

NCT03588286
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Electrophysiology study (EPS), Standard Care, Cardiac Magnetic Resonance (CMR)
Procedure · Other
Lead sponsor
Western Sydney Local Health District
Other
Eligibility
18 Years to 85 Years
Enrollment
1,058 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 9, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillators

NCT03374891
View directory record Official record
Conditions
Heart Failure, Systolic, Heart Failure
Interventions
Educational video and/or handout
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
790 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 9, 2026, 5:50 AM EDT