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ClinicalTrials.gov public records Last synced Oct 5, 2026, 3:43 PM EDT

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Showing 25–48 of 130 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Negative Pressure Wound Therapy (NPWT) Clear all
Completed Not applicable Interventional Results available

PICO Breast Reduction Clinical Study Looking at Incision Healing Complications

NCT01640366
View directory record Official record
Conditions
Delayed Healing
Interventions
PICO
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • The Bronx, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 5, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Incisional Wound Vac in Obese Patients

NCT00789659
View directory record Official record
Conditions
Wound Infection, Postoperative Complication
Interventions
Negative pressure dressing
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional

Wound Vac Polypropylene Suture Pilot Study

NCT02929238
View directory record Official record
Conditions
Wound Vac, Suture
Interventions
Polypropylene Suture Right Side, Polypropylene Suture Left Side
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 13, 2018 · Synced Oct 5, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Negative Pressure Wound Therapy vs Standard Care Dressing

NCT03566641
View directory record Official record
Conditions
Negative-Pressure Wound Therapy
Interventions
Negative pressure wound therapy, standard care dressing
Device · Other
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 5, 2026, 3:43 PM EDT
Recruiting Phase 3 Interventional

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

NCT05615844
View directory record Official record
Conditions
Open tíbia Fracture
Interventions
Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy
Drug · Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
30
States / cities
Chandler, Arizona • Tucson, Arizona • Davis, California + 25 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 5, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Results available

VAC Bioburden Wound Care Assessment

NCT04826965
View directory record Official record
Conditions
Upper Extremity Wound, Lower Extremity Wound, Soft Tissue Abscesses, Traumatic Wounds
Interventions
Wound Vac is applied
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2023 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prophylactic Incisional Care in Obese Women at Cesarean

NCT02578745
View directory record Official record
Conditions
Wound Infections
Interventions
Prophylactic NPWT (PICO system), Standard Dressing
Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Use of EZCare/V1STA in the Management of Acute and Chronic Wounds

NCT00994162
View directory record Official record
Conditions
Wounds
Interventions
EZCare/V1STA Negative Pressure Wound Therapy System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 5, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Incisional Negative Pressure Dressing on Clean Closed Groin Incisions

NCT02006511
View directory record Official record
Conditions
Complication of Surgical Procedure
Interventions
Incisional Neg Pressure Wound Therapy (Prevena™), Standard of Care wound therapy
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 5, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Results available

Standard Versus PICO Dressings in Lower-Extremity Bypass Patients

NCT02492854
View directory record Official record
Conditions
Of Bypass Graft of the Extremities, Peripheral Arterial Disease, Vascular Diseases, Cardiovascular Diseases
Interventions
PICO Single-Use Negative Pressure Dressings, Sterile Gauze Dressings
Device · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
35 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 5, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery

NCT02799667
View directory record Official record
Conditions
Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
Interventions
Standard Dressing, Negative Pressure Wound Therapy Dressing
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 5, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

The Role of VAC Therapy Devices in Promoting Closure of Enterocutaneous Fistulae

NCT02519192
View directory record Official record
Conditions
Fistulae
Interventions
V.A.C.Ulta™ Negative Pressure Wound Therapy System, Vac sponge irrigations, ostomy bag, wet to dry dressings
Device · Procedure
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Oct 5, 2026, 3:43 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Needle-Aspirated Compression Dressing Following Ostomy Reversal

NCT03703661
View directory record Official record
Conditions
Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
Interventions
Needle-Aspirated Negative Pressure Dressing, Control
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 5, 2026, 3:43 PM EDT
Active, not recruiting Not applicable Interventional

Delayed Primary Closure Using Negative Pressure Wound Therapy

NCT04042259
View directory record Official record
Conditions
Infection Abdominal
Interventions
Abthera, Open adbdomen for post-laparotomy without NPWT device
Device · Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study Evaluating the Safety and Efficacy of a Patient-Specific Enteroatmospheric Fistula Isolation and Management Device Independent of Negative Pressure Wound Therapy

NCT04978090
View directory record Official record
Conditions
Fistula, Abdominal Injury, Negative Pressure Wound Therapy
Interventions
3D printed EAF management device
Device
Lead sponsor
Andrew Bernard
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 5, 2026, 3:43 PM EDT
Terminated Not applicable Interventional Results available

Negative Pressure Wound Therapy With Instillation of Saline Solution Versus Collagenase Ointment in Full-thickness Wounds

NCT03722485
View directory record Official record
Conditions
Wounds and Injuries, Wound Healing, Granulation Tissue
Interventions
Negative Pressure Therapy w/ instillation and dwell (NPWTi-d), Collagenase Ointment
Device · Biological
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
10
States / cities
Phoenix, Arizona • Tucson, Arizona • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)

NCT00952120
View directory record Official record
Conditions
Wound Healing
Interventions
GSUC, VAC
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

NCT02020018
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Prevena Incision Management System, Conventional sterile dry wound dressing
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
1,869 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT)

NCT02470806
View directory record Official record
Conditions
Venous Leg Ulcers, Diabetic Foot Ulcers
Interventions
PICO System, tNPWT System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
15
States / cities
Carlsbad, California • Fresno, California • Martinez, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 5, 2026, 3:43 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Regenn® Therapy System Safety Study

NCT06259409
View directory record Official record
Conditions
Surgical Wound
Interventions
Regenn® Negative Pressure Therapy System, Prevena™ Incision Management System
Device
Lead sponsor
Progenerative Medical, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 5, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR

NCT04906408
View directory record Official record
Conditions
Abdomen Hernia
Interventions
Prevena, Prineo, Traditional
Device · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 5, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Comparison of Two Methods of Negative Pressure Wound Therapy

NCT00724750
View directory record Official record
Conditions
Acute Wounds From Trauma, Dehiscence or Surgical Complications
Interventions
Gauze suction (G-SUC), Vacuum Assisted Closure Device (VAC)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Oct 5, 2026, 3:43 PM EDT
Withdrawn Not applicable Interventional

Clinical Evaluation of the SNaP Wound Care System

NCT01113658
View directory record Official record
Conditions
Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers, Venous Stasis Ulcers
Interventions
SNaP Wound Care System
Device
Lead sponsor
3M
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Daly City, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Oct 5, 2026, 3:43 PM EDT
Not listed No phase listed Observational

Assess the Efficacy of Prevena Plus vs SOC to Closed Incision in Pts Undergoing CAWR and Other Laparotomy Procedures.

NCT04539015
View directory record Official record
Conditions
Hernia
Interventions
Prevena Plus
Device
Lead sponsor
New York Medical College
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 5, 2026, 3:43 PM EDT