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ClinicalTrials.gov public records Last synced Oct 29, 2026, 5:49 PM EDT

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Showing 553–576 of 1,740 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pressure control Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Exercise & Diet Effects on CV Risk in Firefighters

NCT03344198
View directory record Official record
Conditions
Cardiovascular Risk Factor, Blood Pressure, Exercise, Diet Modification, Health Promotion
Interventions
Circuit Training exercise & Modified Mediterranean diet
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Follow-up Comparison of Active Versus Passive Manual Therapy in Patients With Low Back Pain

NCT03758807
View directory record Official record
Conditions
Low Back Pain, Manual Therapy, Education
Interventions
Manual Therapy with Traditional Biomechanical Explanation, Manual Therapy with Neuroplastiicity Explanation
Other
Lead sponsor
St. Ambrose University
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 29, 2026, 5:49 PM EDT
Not yet recruiting Not applicable Interventional

Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension

NCT07679984
View directory record Official record
Conditions
Hypertension, Essential (Primary) Hypertension
Interventions
Mindfulness in Motion
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 29, 2026, 5:49 PM EDT
Not yet recruiting Not applicable Interventional

Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA

NCT05618444
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Automated Management (AM)
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Fontana, California • Kansas City, Kansas • Danville, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 29, 2026, 5:49 PM EDT
Suspended Phase 1 Interventional

Trazodone Dose Tolerance and APAP Adherence

NCT02945644
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Trazodone, Placebo
Drug
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Phase 2 Interventional Results available

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

NCT05103332
View directory record Official record
Conditions
Hypertension
Interventions
Indapamide, Amlodipine, Olmesartan, Placebo, Zilebesiran
Drug
Lead sponsor
Alnylam Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
663 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
74
States / cities
Mesa, Arizona • Tempe, Arizona • Bell Gardens, California + 62 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional

ASPIRE: Adapting Self-Blood Pressure Monitoring to Reduce Health Disparities

NCT06175793
View directory record Official record
Conditions
Hypertension
Interventions
ASPIRE Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Phase 2 Interventional

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)

NCT06272487
View directory record Official record
Conditions
High Cardiovascular Risk, Hypertension
Interventions
Zilebesiran, Placebo
Drug
Lead sponsor
Alnylam Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
139
States / cities
Alexander City, Alabama • Daphne, Alabama • Foley, Alabama + 115 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury

NCT03602014
View directory record Official record
Conditions
Hypotension, Orthostatic, Hypotension, Spinal Cord Injuries
Interventions
Northera, Placebo
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 29, 2026, 5:49 PM EDT
Terminated Not applicable Interventional Results available

POSITIVE Stroke Clinical Trial

NCT01852201
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Endovascular Mechanical Thrombectomy
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
20
States / cities
Phoenix, Arizona • Los Angeles, California • Englewood, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional

A Case-Control Study of Negative Pressure Platform Wound Devices (NP-PWD) for Skin and Soft Tissue Defects

NCT06552481
View directory record Official record
Conditions
Skin Wound, Soft Tissue Injuries
Interventions
NP-PWD, Wound Vac
Device
Lead sponsor
The Metis Foundation
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Oct 29, 2026, 5:49 PM EDT
Terminated Not applicable Interventional

Noninvasive Estimation of Work of Breathing

NCT02867228
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome
Interventions
changes in ventilator settings
Other
Lead sponsor
Respironics, California, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot

NCT04265807
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional

MI-BP: mHealth to Improve Blood Pressure Control

NCT02955537
View directory record Official record
Conditions
Hypertension
Interventions
MI-BP
Other
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 70 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 29, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

Lifestyle Intervention In CKD

NCT07633145
View directory record Official record
Conditions
Chronic Kidney Disease, Hypertension
Interventions
Multi-component lifestyle intervention, Usual Care Control
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 29, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems

NCT06959277
View directory record Official record
Conditions
Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy With Type 2 Diabetes, Balance Control in Elderly, Gait Disorders
Interventions
Walkasins, Fall Prevention Training
Device · Other
Lead sponsor
RxFunction Inc.
Industry
Eligibility
55 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Mesa, Arizona • Boston, Massachusetts • Saint Paul, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 29, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exercise, Hypertension, and Gut Dysbiosis in African Americans

NCT03897777
View directory record Official record
Conditions
Hypertension
Interventions
Exercise Training effect on Hypertension and Gut Dysbiosis
Behavioral
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
30 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2030
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 29, 2026, 5:49 PM EDT
Withdrawn Not applicable Interventional

Team Based Equity Conscious Telemedicine Approach to Hypertension

NCT06424730
View directory record Official record
Conditions
Hypertension
Interventions
Feasibility Interview, Team Based Equity Conscious Telemedicine Hypertension Intervention, Usual Care
Other · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Heel Offloading Devices for Reducing Heel Contact Pressures in Healthy Volunteers

NCT02811965
View directory record Official record
Conditions
Heel Pressure Ulceration Prevention Strategies
Interventions
Pillow Condition 1, Pillow Condition 2, Heel Foam Pillow, Offloading Device A, Offloading Device B, Offloading Device C
Other · Device
Lead sponsor
DeRoyal Industries, Inc.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Smart Phone Medication Adherence Saves Kidneys--SMASK

NCT02827695
View directory record Official record
Conditions
Kidney Transplantation, Medication Adherence, Hypertension
Interventions
SMASK, EnhancedSC
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Hypertension With Unsatisfactory Sleep Health

NCT02508129
View directory record Official record
Conditions
Insomnia, Hypertension
Interventions
Brief Behavioral Treatment for Insomnia, Sleep Healthy Using the Internet, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
542 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

CPAP (Continuous Positive Airway Pressure) Study Educational Materials and Usage Feedback to Promote CPAP Adherence

NCT02195531
View directory record Official record
Conditions
Adherence
Interventions
Education and feedback
Behavioral
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
6
States / cities
Glendale, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 29, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Impact of Pleural Manometry on Chest Discomfort After Therapeutic Thoracentesis

NCT02677883
View directory record Official record
Conditions
Pleural Effusion
Interventions
Manometry-guided thoracentesis, Symptom-guided thoracentesis
Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
19 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 29, 2026, 5:49 PM EDT
Not listed No phase listed Observational

Gut Permeability-related Inflammation and Cardiovascular Disease Risk in Normal-weight and Metabolically Healthy Obesity

NCT05308394
View directory record Official record
Conditions
Obesity
Interventions
No experimental intervention will take place - the study is cross-sectional. Each participant will provide biological samples.
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Timeline
2022
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 15, 2022 · Synced Oct 29, 2026, 5:49 PM EDT