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ClinicalTrials.gov public records Last synced Oct 30, 2026, 5:45 PM EDT

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Showing 433–456 of 1,170 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Control Group Clear all
Not yet recruiting Phase 4 Interventional

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

NCT07387315
View directory record Official record
Conditions
Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
Interventions
Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask
Drug · Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Phase 2 Interventional

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT

NCT04862468
View directory record Official record
Conditions
Thrombosis, Deep Vein, Iliofemoral; Thrombosis
Interventions
Perivascular dexamethasone, Perivascular sham
Combination Product
Lead sponsor
Mercator MedSystems, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
20
States / cities
Scottsdale, Arizona • Orange, California • Darien, Connecticut + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Not applicable Interventional

Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

NCT03992378
View directory record Official record
Conditions
Septic Shock
Interventions
Low Level Transcutaneous Vagus Nerve Stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
14
States / cities
Tucson, Arizona • New Haven, Connecticut • Weston, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Role of 905-nm Laser Light in the Delay of Muscle Fatigue

NCT03461731
View directory record Official record
Conditions
Muscle Fatigue
Interventions
Control, 800 nm laser, combination laser, 905 nm laser
Device
Lead sponsor
College of Charleston
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Oct 30, 2026, 5:45 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke

NCT04013256
View directory record Official record
Conditions
Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
Interventions
Cigarette Smoke, Clean Air and Clean Clothing/Sham exposure
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers

NCT02355002
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia

NCT02226796
View directory record Official record
Conditions
Aphasia
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
20 Years to 85 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 30, 2026, 5:45 PM EDT
Terminated No phase listed Interventional Results available

Vestibular Stimulation to Trigger Adipose Loss Clinical Trial

NCT03138369
View directory record Official record
Conditions
Obesity, Obesity, Abdominal, Metabolic Syndrome, Weight Loss
Interventions
Vestibular nerve stimulator, Sham vestibular stimulation
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Not applicable Interventional

Investigation of PEMF Therapy for Female Patients With IC/BPS

NCT05149573
View directory record Official record
Conditions
Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
Interventions
Pulsed Electromagnetic Field (PEMF) Device, Sham Pulsed Electromagnetic Field (PEMF) Device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Not applicable Interventional

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

NCT06559891
View directory record Official record
Conditions
Hypertension
Interventions
TIVUS™ Renal Denervation System, Sham
Device · Other
Lead sponsor
SoniVie Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
34
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Jonesboro, Arkansas + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Beta Events and Sensory Perception

NCT04062318
View directory record Official record
Conditions
Beta Rhythm, Tactile Perception
Interventions
Online Active SI-Hand TMS, Online Sham SI-Hand TMS, Online Active Control TMS
Device
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Shifting Sleep Timing in Teens

NCT05808179
View directory record Official record
Conditions
Sleep Insufficiency, Sleep, Adolescent Behavior
Interventions
Light, CBT, Sham Light
Device · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 18 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing and Interactive Concussion Education Platform to Current Education Standards

NCT04122274
View directory record Official record
Conditions
Concussion, Brain
Interventions
NCAA education sheet, Sham Intervention, Decision-based interactive concussive education platform
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acupuncture and Acupressure for Postoperative Nausea and Vomiting in Children Undergoing Outpatient Middle Ear Surgery

NCT03380182
View directory record Official record
Conditions
Nausea, Vomiting, PONV
Interventions
Acupressure Band, Sham Band
Other
Lead sponsor
University of California, Davis
Other
Eligibility
2 Years to 18 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Phase 3 Interventional Results available

Clinical Study Comparing Two Models of a Travoprost Intraocular Implant

NCT03868124
View directory record Official record
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
G2-TR intraocular implant containing travoprost, Sham surgery + active-comparator eye drops
Combination Product · Drug
Lead sponsor
Glaukos Corporation
Industry
Eligibility
18 Years and older
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 30, 2026, 5:45 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Cranial Electric Stimulation to Modify Suicide Risk Factors in Psychiatric Inpatients.

NCT02846740
View directory record Official record
Conditions
Suicide, Depression, Anxiety, Insomnia, Agitation
Interventions
Alpha-Stim®., Montgomery-Åsberg Depression Rating Scale, Hamilton Anxiety Rating Scale, The Pittsburgh Sleep Quality Index and agitated behavior Scale
Device · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Breathe for Hot Flashes Randomized Controlled Trial

NCT00819182
View directory record Official record
Conditions
Hot Flashes
Interventions
Paced respiration, Sham comparator: fast shallow breathing
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Phase 2 Interventional

Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma

NCT07120503
View directory record Official record
Conditions
Asthma
Interventions
WIN378, Placebo
Drug
Lead sponsor
Windward Bio
Industry
Eligibility
18 Years to 75 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
21
States / cities
Los Angeles, California • San Jose, California • Melbourne, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 30, 2026, 5:45 PM EDT
Withdrawn Not applicable Interventional

Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations

NCT01497691
View directory record Official record
Conditions
Asthma
Interventions
NIPPV (PALMtop PTV), Volumetric CO2 (NM3), USCOM
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Oct 30, 2026, 5:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Following Hip Arthroscopy

NCT04113759
View directory record Official record
Conditions
Labral Tear, Glenoid, Femoral Acetabular Impingement
Interventions
Blood Flow Restriction Rehabilitative Therapy, Sham BFR Rehabilitative Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acupuncture for Post-Operative Pain Control for Patients Undergoing Gynecological Surgery

NCT02855567
View directory record Official record
Conditions
Post-operative Pain, Gynecological Surgery, Acupuncture
Interventions
Acupuncture needles
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 30, 2026, 5:45 PM EDT
Completed Phase 2 Interventional Results available

Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)

NCT06011798
View directory record Official record
Conditions
Diabetic Macular Edema, Retinal Disease, Macular Edema, Diabetes Mellitus, Diabetic Retinopathy, Retinal Degeneration, Retinal Diseases, Eye Diseases, Edema
Interventions
Aflibercept, foselutoclax
Drug
Lead sponsor
Unity Biotechnology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
19
States / cities
Bakersfield, California • Beverly Hills, California • Huntington Beach, California + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 30, 2026, 5:45 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Interactions Between Placebo Effects and Mindful Awareness State

NCT07108101
View directory record Official record
Conditions
Placebo Effect, Mindfulness, Pain, Transcranial Direct Current Stimulation (tDCS)
Interventions
tDCS stimulation (sham), tDCS stimulation (real), Mindful state induction, No minfulness induction
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 30, 2026, 5:45 PM EDT