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ClinicalTrials.gov public records Last synced Sep 22, 2026, 4:36 PM EDT

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Showing 1–24 of 112 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham laser treatment Clear all
Not yet recruiting Not applicable Interventional

Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain

NCT07832422
View directory record Official record
Conditions
Low Back Pain, Myofascial Pain Syndromes
Interventions
Ischemic Compression, Low-Level Laser Therapy, Exercise Program, Sham Low-Level Laser Therapy
Other · Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Recruiting Not applicable Interventional

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

NCT07509177
View directory record Official record
Conditions
Epilepsy
Interventions
Photobiomodulation
Other
Lead sponsor
Cynthia Kerson
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
North Miami, Florida • Cincinnati, Ohio • Warren, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Recruiting Phase 1Phase 2 Interventional

Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains

NCT06795451
View directory record Official record
Conditions
Depression - Major Depressive Disorder
Interventions
transcutaneous spinal direct current stimulation
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 60 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Treatment of Androgenetic Alopecia in Males With Theradome™ LH80 PRO

NCT02528552
View directory record Official record
Conditions
Androgenetic Alopecia
Interventions
LH80 PRO, Sham Device
Device
Lead sponsor
Theradome, Inc.
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Los Angeles, California • Newnan, Georgia • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2016 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional Results available

Pediatric Laser Acupuncture and Renal Biopsy

NCT01879826
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Aculaser applied to kidney points, Aculaser applied to sham points
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 22, 2026, 4:36 PM EDT
Terminated Not applicable Interventional Results available

Safety and Effectiveness of Ozurdex Steroid Implants for DME After Vitrectomy Surgery

NCT01788475
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Dexamethasone
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Peabody, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Phase 3 Interventional Results available

Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension

NCT02507687
View directory record Official record
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
Bimatoprost SR, Sham Bimatoprost SR, Selective Laser Trabeculoplasty, Sham Selective Laser Trabeculoplasty
Drug · Procedure
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
51
States / cities
Dothan, Alabama • Glendale, Arizona • Phoenix, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Phase 1Phase 2 Interventional Results available

HORNBILL: A Study to Test Different Doses of BI 764524 in Patients Who Have Had Laser Treatment for a Type of Diabetic Eye Disease Called Diabetic Retinopathy With Diabetic Macular Ischemia

NCT04424290
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
BI 764524, Sham control of BI 764524
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
13
States / cities
Dothan, Alabama • Beverly Hills, California • Palo Alto, California + 10 more
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Sep 22, 2026, 4:36 PM EDT
Withdrawn Phase 2 Interventional

Laser Therapy for Diabetic Peripheral Neuropathic Pain

NCT02328911
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Laser treatment, Sham treatment
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 27, 2015 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional

MacTel Laser Study

NCT03321916
View directory record Official record
Conditions
Macular Telangiectasia
Interventions
577-nm PASCAL laser
Device
Lead sponsor
The Lowy Medical Research Institute Limited
Other
Eligibility
21 Years to 79 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Sep 22, 2026, 4:36 PM EDT
Recruiting Not applicable Interventional

Effects of Transcranial Photobiomodulation in ADHD

NCT07203092
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Active transcranial photobiomodulation, Sham transcranial photobiomodulation
Device
Lead sponsor
Francisco Gonzalez-Lima, PhD
Other
Eligibility
18 Years to 44 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Low Level Laser Therapy to Reduce Body Circumference in Obese Individuals

NCT01821352
View directory record Official record
Conditions
Obesity
Interventions
Erchonia Obesity Laser, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Noblesville, Indiana • Bloomfield Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 10, 2015 · Synced Sep 22, 2026, 4:36 PM EDT
Withdrawn Not applicable Interventional

Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia

NCT03390049
View directory record Official record
Conditions
Vestibulodynia
Interventions
Fractional CO2 Laser Treatment, Sham Laser Treatment
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2019 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Phase 2Phase 3 Interventional Results available

A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.

NCT00605280
View directory record Official record
Conditions
Macular Edema Associated With Diabetes Mellitus
Interventions
Standard of Care, Macugen
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
28
States / cities
Phoenix, Arizona • Tucson, Arizona • Los Angeles, California + 24 more
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Sep 22, 2026, 4:36 PM EDT
Terminated Not applicable Interventional

Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy

NCT02898233
View directory record Official record
Conditions
Depression
Interventions
Deprexis, Active low-level light therapy, Sham low-level light therapy
Other · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MonaLisa Touch Randomized Double-Blind Placebo Controlled Study

NCT03331328
View directory record Official record
Conditions
Genitourinary Syndrome of Menopause
Interventions
MonaLisa Touch
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Sep 22, 2026, 4:36 PM EDT
Not yet recruiting Not applicable Interventional

Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)

NCT07079969
View directory record Official record
Conditions
Chronic Knee Pain
Interventions
Photobiomodulation therapy (PBM) device, Sham PBM device
Device
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Intervention With Near Infrared Stimulation

NCT03551392
View directory record Official record
Conditions
Aging
Interventions
Medx Console System, Sham Medx Console System, Vielight 810 intranasal stand alone unit, Sham Vielight 810 intranasal stand alone unit
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Efficacy of a Dual-Frequency LLLT Device With a Sham Device as a Therapy for Adipose Tissue Loss

NCT03811093
View directory record Official record
Conditions
Obesity, Body Weight, Fat Burn, Cellulite, Abdominal Fat, Adipose Tissue Atrophy
Interventions
Care as Usual Group, Sham Group
Device
Lead sponsor
IR Technology, LLC
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Hixson, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Vascular and Neurocognitive Health

NCT06497413
View directory record Official record
Conditions
Cognitive Decline, Cognitive Dysfunction, Alzheimer Disease, Vascular Disease, Peripheral
Interventions
Transcranial Photobiomodulation, Transcranial Photobiomodulation helmet (Neuradiant 1070 Plus) with no light administered
Device
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 22, 2026, 4:36 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of LASER Photobiomodulation Therapy on Chronic Pain and Opioid Weaning

NCT03437967
View directory record Official record
Conditions
Chronic Pain
Interventions
LightForce EXPi
Device
Lead sponsor
LiteCure LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2019 · Synced Sep 22, 2026, 4:36 PM EDT
Not listed Not applicable Interventional

Phoenix Thera-Lase for Treating Chronic Pain in Patients Taking Opioid on a PRN Basis

NCT02964000
View directory record Official record
Conditions
Pain
Interventions
Low level 1 Watt, Phoenix Thera-Lase System 42, Phoenix Thera-Lase System 74
Device
Lead sponsor
Phoenix Thera-lase Systems, LLC
Industry
Eligibility
25 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 22, 2026, 4:36 PM EDT
Not yet recruiting Not applicable Interventional

Treatment of Chronic Lower Back Pain With a Combination of Electrical Stimulation, LED, and Laser Therapy

NCT07313826
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Active Neurolumen, Inactive Neurolumen
Device
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 22, 2026, 4:36 PM EDT
Completed Phase 4 Interventional Results available

Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation

NCT04187053
View directory record Official record
Conditions
DENT IMPLANTS, LASER
Interventions
Conventional mechanical therapy, Saline, Methylene Blue, Light emitting laser, Non-light emitting laser
Procedure · Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Sep 22, 2026, 4:36 PM EDT