- Conditions
- Hypertension
- Interventions
- Renal Denervation
- Device
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 3
- States / cities
- Springfield, Illinois • Minneapolis, Minnesota • Cleveland, Ohio
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Showing 1–10
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- Conditions
- Hypertension, Vascular Diseases, Cardiovascular Diseases
- Interventions
- Symplicity Spyral™ multi-electrode renal denervation system, Sham Procedure
- Device · Procedure
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 20 Years to 80 Years
- Enrollment
- 337 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 32
- States / cities
- Huntsville, Alabama • Stanford, California • New Haven, Connecticut + 26 more
- Conditions
- Atrial Fibrillation, Hypertension
- Interventions
- Symplicity Spyral™ Multi-Electrode Renal Denervation Catheter, Arctic Front Advance™ Cardiac Cryoablation System
- Device
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 9
- States / cities
- Sacramento, California • Burlington, Massachusetts • Marquette, Michigan + 5 more
- Conditions
- Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
- Interventions
- Renal Denervation (Symplicity Spyral™)
- Device
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,899 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2029
- U.S. locations
- 76
- States / cities
- Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 67 more
- Conditions
- Hypertension, Vascular Diseases, Cardiovascular Diseases
- Interventions
- Renal Denervation (Symplicity Spyral™)
- Device
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 20 Years to 80 Years
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 3
- States / cities
- Stanford, California • Atlanta, Georgia • Dallas, Texas
- Conditions
- Hypertension, Vascular Diseases, Cardiovascular Diseases
- Interventions
- Symplicity Spyral™ multi-electrode renal denervation system, Sham Procedure
- Device · Procedure
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 20 Years to 80 Years
- Enrollment
- 366 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2023
- U.S. locations
- 30
- States / cities
- Huntsville, Alabama • Scottsdale, Arizona • Los Angeles, California + 26 more
- Conditions
- Hypertension, Cardiovascular Diseases, Vascular Diseases
- Interventions
- Renal Denervation (Symplicity Spyral™)
- Device
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Heart Failure
- Interventions
- Symplicity Renal Denervation
- Device
- Lead sponsor
- Adrian Hernandez
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 12
- States / cities
- Atlanta, Georgia • Boston, Massachusetts • Rochester, Minnesota + 5 more
- Conditions
- Hypertension, Vascular Diseases, Cardiovascular Diseases
- Interventions
- Renal Denervation using the Symplicity Renal Denervation System, Sham Renal Denervation, Renal Angiography
- Device · Other
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 3
- States / cities
- Atlanta, Georgia • Durham, North Carolina • Charleston, South Carolina
- Conditions
- Uncontrolled Hypertension
- Interventions
- Renal denervation (Symplicity Catheter System), Renal angiogram
- Device · Diagnostic Test
- Lead sponsor
- Medtronic Vascular
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 535 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 79
- States / cities
- Birmingham, Alabama • La Jolla, California • Los Angeles, California + 61 more