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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:36 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2689–2712 of 3,113 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Treatment of depression Clear all

Conditions: Heart Failure, Pulmonary Disease, Chronic Obstructive, Interstitial Lung Disease
Interventions: Virtual Nurse and Social Worker Palliative Care Team, Enhanced Implementation Support, Standard Implementation Support; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 7
States / cities: Phoenix, Arizona • Long Beach, California • Aurora, Colorado + 4 more

Conditions: Antidepressant Induced Sexual Dysfunction
Interventions: Maca Root, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Disordered Eating Behaviors
Interventions: The BEET Diabetes Program, Cognitive Behavioral Therapy Guided Self-Help; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Depressive Symptoms
Interventions: Syrenity App; Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
Interventions: Real LED Treatment, Sham LED Treatment; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 38 Years to 65 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: San Francisco, California • Boston, Massachusetts

Conditions: Heart Failure, Depression
Interventions: sertraline; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Major Depressive Disorder
Interventions: CP-601,927, Placebo; Drug · Other
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 297 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 58
States / cities: Little Rock, Arkansas • Beverly Hills, California • Garden Grove, California + 44 more

Conditions: Bipolar Disorder
Interventions: JNJ-55308942, Placebo; Drug
Lead sponsor: Janssen Pharmaceutica N.V., Belgium; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 18
States / cities: Huntsville, Alabama • Little Rock, Arkansas • Lemon Grove, California + 15 more

Conditions: Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions: Transcranial Magnetic Stimulation (TMS), Task, fMRI-guided TMS target; Device · Behavioral · Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Chronic Kidney Diseases, Major Depressive Disorder, End Stage Kidney Disease (ESRD)
Interventions: Bupropion, Behavioral activation therapy, Placebo, Clinical Management; Drug · Behavioral · Other
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 4
States / cities: Stony Brook, New York • Dallas, Texas • Seattle, Washington

Conditions: MDD
Interventions: Transcranial Magnetic Stimulation; Device
Lead sponsor: Neuronetics; Other
Eligibility: 12 Years to 21 Years
Enrollment: 7,690 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Malvern, Pennsylvania

Conditions: Depression
Interventions: Riluzole, placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 3
States / cities: New Haven, Connecticut • Boston, Massachusetts • Houston, Texas

Conditions: Major Depressive Disorder
Interventions: eCBT Mood; Behavioral
Lead sponsor: MindApps; Industry
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Leesburg, Florida • Orlando, Florida

Conditions: Alcohol Abuse
Interventions: ABCT_Military; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Acute Coronary Syndrome, Heart Failure, Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions: Collaborative Care; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 3
States / cities: Boston, Massachusetts • Salem, Massachusetts

Conditions: Depression
Interventions: BioKefir, Non-fermented milk; Dietary Supplement
Lead sponsor: Rush University Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Bipolar Disorder
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Not listed
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Depression
Interventions: Neurofeedback; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 13 Years to 15 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Major Depressive Disorder, Depression
Interventions: TC-5214, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 2,409 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 79
States / cities: Birmingham, Alabama • Tucson, Arizona • Conway, Arkansas + 76 more

Conditions: Hepatitis C, Depressive Disorder, Major, Depressive Disorder, Depression, HIV Infections
Interventions: Hepatitis C educational support groups, Cognitive Behavioral Therapy skills based group sessions; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: Heart Disease, Ischemic Heart Disease, Coronary Artery Disease, Coronary Artery Disease (CAD)
Interventions: Cell Therapy; Other
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 85 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 2
States / cities: Bethesda, Maryland

Conditions: Depression, Depressive Disorder, Behavioral Symptoms, Mood Disorders, Mental Disorders
Interventions: Growth Mindset Online Single-Session Program, Self-Kindness Online Single-Session Program, Supportive Therapy Online Single-Session Program (Control); Behavioral
Lead sponsor: Child Mind Institute; Other
Eligibility: 11 Years to 17 Years
Enrollment: 501 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Acquired Immunodeficiency Syndrome, HIV Infections, Depression
Interventions: Massage Therapy; Procedure
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 16 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depression, Unipolar, Mental Health Disorder
Interventions: Engage-M, Wellness in Mind and Body; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 55 Years to 100 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD

Study of Maca Root for the Treatment of Antidepressant-Induced Sexual Dysfunction in Females

The BEET Diabetes Feasibility Trial

Syrenity App for Depression

Scalp Application of LED Therapy to Improve Thinking and Memory in Veterans With Gulf War Illness

Vascular Effects of Sertraline in Heart Failure

A Study Of The Efficacy And Safety Of CP-601,927 Augmentation Of Antidepressant Therapy In Major Depression

A Study of JNJ-55308942 in the Treatment of Bipolar Depression

Accelerated TMS to a Novel Brain Target in MDD and PTSD

Combination of Novel Therapies for CKD Comorbid Depression

A Retrospective Study to Evaluate NeuroStar® Advanced Therapy in Adolescents

Efficacy and Tolerability of Riluzole in Treatment Resistant Depression

Efficacy of Electronic Cognitive Behavioral Therapy Application to Treat Major Depressive Disorder

Adapting Alcohol Behavioral Couple Therapy for Service Members in Post-Deployment

Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety

Fermented Milk Product With Probiotic and Its Impact on Mood of Patients With Treatment Resistant Depression

The Treatment of Children and Adolescents With Treatment-Resistant Depression

Adolescent Attention to Emotion Study

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder

Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients

Stem Cell Injection to Treat Heart Damage During Open Heart Surgery

Targeting Adolescent Depressive Symptoms Via Brief, Web-Based Interventions

Treatment of Depression With Massage in HIV

Reaching and Engaging Depressed Senior Center Clients (REDS)