- Conditions
- Colorectal Adenoma, Stage 0 Colorectal Cancer AJCC v8, Stage I Colorectal Cancer AJCC v8, Stage II Colorectal Cancer AJCC v8, Stage IIA Colorectal Cancer AJCC v8, Stage IIB Colorectal Cancer AJCC v8, Stage IIC Colorectal Cancer AJCC v8, Stage III Colorectal Cancer AJCC v8, Stage IIIA Colorectal Cancer AJCC v8, Stage IIIB Colorectal Cancer AJCC v8, Stage IIIC Colorectal Cancer AJCC v8
- Interventions
- Linaclotide, Placebo
- Drug · Other
- Lead sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
- Other
- Eligibility
- 18 Years to 80 Years · Female only
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 3
- States / cities
- Philadelphia, Pennsylvania • Seattle, Washington
Search Results
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Showing 1–11
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Irritable Bowel Syndrome Characterized by Constipation
- Interventions
- Linaclotide, Placebo
- Drug
- Lead sponsor
- Ironwood Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 614 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 79
- States / cities
- Huntsville, Alabama • Phoenix, Arizona • Tucson, Arizona + 67 more
- Conditions
- Constipation
- Interventions
- MD-1100 Acetate
- Drug
- Lead sponsor
- Ironwood Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 14
- States / cities
- Huntsville, Alabama • North Little Rock, Arkansas • Boynton Beach, Florida + 11 more
- Conditions
- Irritable Bowel Syndrome With Constipation, Functional Constipation
- Interventions
- Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 and LIN-MD-64 completers), Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 381 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 65
- States / cities
- Birmingham, Alabama • Foley, Alabama • Saraland, Alabama + 50 more
- Conditions
- Functional Constipation, Irritable Bowel Syndrome With Constipation
- Interventions
- Linaclotide, Placebo
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 438 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 79
- States / cities
- Birmingham, Alabama • Foley, Alabama • Saraland, Alabama + 62 more
- Conditions
- Chronic Constipation, Diabete Mellitus
- Interventions
- linaclotide or placebo
- Drug
- Lead sponsor
- Texas Tech University Health Sciences Center, El Paso
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2027
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- Linaclotide, Matching Placebo
- Drug
- Lead sponsor
- Ironwood Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,223 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 95
- States / cities
- Huntsville, Alabama • Phoenix, Arizona • Tucson, Arizona + 81 more
- Conditions
- Irritable Bowel Syndrome With Constipation
- Interventions
- Linaclotide or Matching Placebo
- Drug
- Lead sponsor
- Ironwood Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 805 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 107
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 97 more
- Conditions
- Functional Constipation (FC), Chronic Idiopathic Constipation (CIC)
- Interventions
- Placebo for Linaclotide, Linaclotide
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 2 Years to 5 Years
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 38
- States / cities
- Foley, Alabama • Phoenix, Arizona • Hot Springs, Arkansas + 33 more
- Conditions
- Irritable Bowel Syndrome With Constipation
- Interventions
- Linaclotide Dose A, Linaclotide Dose B, Linaclotide Dose C, Linaclotide Approved Adult Dose, Matching Placebo
- Drug
- Lead sponsor
- Forest Laboratories
- Industry
- Eligibility
- 7 Years to 17 Years
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 46
- States / cities
- Hot Springs, Arkansas • Little Rock, Arkansas • Anaheim, California + 39 more
- Conditions
- Functional Constipation in Children Ages 6-17 Years
- Interventions
- Placebo, LIN Dose A, LIN Dose B, LIN Dose C, LIN 145 µg
- Drug
- Lead sponsor
- Forest Laboratories
- Industry
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 173 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 60
- States / cities
- Hot Springs, Arkansas • Little Rock, Arkansas • Anaheim, California + 51 more