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Clinical trials in Birmingham, Alabama

This page shows live ClinicalTrials.gov search results for Birmingham, Alabama, with direct links to official study records plus on-page filtering and sorting for broad location searches.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 11:00 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
1973
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12
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Birmingham, AL
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Showing 445–456 of 1,973 matching trials in Birmingham, AL.
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Institutions in Birmingham

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Conditions
Locally Advanced Cervical Cancer
Interventions
Placebo, Volrustomig
Other · Biological
Lead sponsor
AstraZeneca
Industry
Eligibility
15 Years and older · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 24 more
Conditions
Obesity
Interventions
Placebo, survodutide
Combination Product
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
5,531 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
153
States / cities
Birmingham, Alabama • Daphne, Alabama • Mobile, Alabama + 135 more
Conditions
Adenocarcinoma, Adenocarcinoma of Colon, Colo-rectal Cancer, Colon Cancer, Colonic Neoplasms, Colorectal Neoplasms, ER Positive Breast Cancer, Estrogen Receptor Positive Tumor, HER-2 Protein Overexpression, HER2 Low Breast Cancer, HER2 Low Breast Carcinoma, HER2 Mutation-Related Tumors, HER2-negative Breast Cancer, HER2-positive Breast Cancer, HER2-positive Metastatic Breast Cancer, HR Positive, Hormone Receptor Negative Breast Carcinoma, Hormone Receptor-positive Breast Cancer, Metastatic, Metastatic Breast Cancer, Metastatic Cancer, Minimal Residual Disease, Neoplasm, Residual, PR-positive Breast Cancer, Progesterone Receptor-positive Breast Cancer, Rectal Cancer, Rectal Neoplasms, Solid Carcinoma, Solid Tumor, Solid Tumor, Adult, Triple Negative Breast Cancer, ctDNA Monitoring
Interventions
ALX148, Fam-Trastuzumab Deruxtecan-Nxki, TTX-MC138, Tucatinib, Zanidatamab
Drug
Lead sponsor
QuantumLeap Healthcare Collaborative
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
10
States / cities
Birmingham, Alabama • Phoenix, Arizona • Aurora, Colorado + 7 more
Conditions
Asthma
Interventions
ELLIPTA, FF/UMEC/VI, FF/VI
Device · Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years to 17 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
28
States / cities
Birmingham, Alabama • Mobile, Alabama • Paradise Valley, Arizona + 23 more
Active, not recruiting No phase listed Observational Results available

Assessing the Time Demands of Cancer

NCT05708703
Conditions
Metastatic Breast Cancer, Ovarian Cancer
Interventions
Not listed
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
2
States / cities
Birmingham, Alabama • Minneapolis, Minnesota
Conditions
Endometrial Cancer
Interventions
Matching Placebo for selinexor, Selinexor
Drug
Lead sponsor
Karyopharm Therapeutics Inc
Industry
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
68
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 58 more
Conditions
Obesity
Interventions
Cagrilintide, Placebo cagrilintide, Placebo semaglutide, Semaglutide
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
Not listed
Enrollment
3,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
46
States / cities
Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 35 more
Conditions
COPD
Interventions
Ensifentrine, Placebo
Drug
Lead sponsor
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
Industry
Eligibility
40 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Birmingham, Alabama • Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Active, not recruiting Not applicable Interventional

Evolut™ EXPAND TAVR II Pivotal Trial

NCT05149755
Conditions
Moderate Aortic Valve Stenosis
Interventions
Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT)
Device
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
65 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2034
U.S. locations
52
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 47 more
Conditions
Bone Loss
Interventions
E-PRF only, E-PRF/ACS/rhBMP-2, E-PRF/rhBMP-2 (similar ratios), rhBMP-2/E-PRF
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Process Decompression, MILD
Device
Lead sponsor
Stryker Instruments
Industry
Eligibility
18 Years and older
Enrollment
8,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2382
States / cities
Athens, Alabama • Bay Minette, Alabama • Birmingham, Alabama + 1285 more
Conditions
Atopic Dermatitis
Interventions
Not listed
Lead sponsor
Sanofi
Industry
Eligibility
12 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
46
States / cities
Birmingham, Alabama • Montgomery, Alabama • Gilbert, Arizona + 43 more