- Conditions
- Bipolar Disorder Type I With Mania
- Interventions
- KarXT, Lithium, Valproate, Lamotrigine
- Drug
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 52
- States / cities
- Glendale, Arizona • Bentonville, Arkansas • Little Rock, Arkansas + 41 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 25–46
of 22
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Bipolar I Disorder, Mania, Depression
- Interventions
- Cariprazine, Placebo
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 901 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 46
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • Anaheim, California + 39 more
- Conditions
- Bipolar Disorder
- Interventions
- Lithium or Valproate with placebo (PBO), Lithium or Valproate with Aripiprazole
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 29
- States / cities
- Tuscaloosa, Alabama • Anaheim, California • Cerritos, California + 24 more
- Conditions
- Bipolar 1 Disorder
- Interventions
- Endoxifen enteric-coated tablet (8 mg), Placebo Tablets
- Drug
- Lead sponsor
- Jina Pharmaceuticals Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 490 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 12
- States / cities
- Cerritos, California • Los Angeles, California • Orange, California + 8 more
- Conditions
- Bipolar I Disorder, Schizophrenia
- Interventions
- Olanzapine, Standard behavioral weight intervention, Intense behavioral weight intervention
- Drug · Behavioral
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 203 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 4
- States / cities
- Lauderhill, Florida • Bloomfield Hills, Michigan • St Louis, Missouri + 1 more
- Conditions
- Bipolar Disorder
- Interventions
- Olanzapine, Paliperidone ER, Placebo
- Drug
- Lead sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 768 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 16
- States / cities
- Scottsdale, Arizona • Riverside, California • San Diego, California + 13 more
- Conditions
- Bipolar Disorder
- Interventions
- quetiapine SR, quetiapine sr placebo
- Drug
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Bipolar I Disorder, Manic Episode
- Interventions
- Brexpiprazole, Placebo
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 333 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 27
- States / cities
- Little Rock, Arkansas • Bellflower, California • Cerritos, California + 21 more
- Conditions
- Bipolar Disorder
- Interventions
- BHV-7000
- Drug
- Lead sponsor
- Biohaven Therapeutics Ltd.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 32
- States / cities
- Bentonville, Arkansas • Little Rock, Arkansas • Rogers, Arkansas + 26 more
- Conditions
- Bipolar Disorder
- Interventions
- Risperidone
- Drug
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Bipolar Disorder
- Interventions
- Ziprasidone oral capsules
- Drug
- Lead sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Industry
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 169 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 41
- States / cities
- Scottsdale, Arizona • San Diego, California • Aurora, Colorado + 33 more
- Conditions
- Bipolar I Disorder, Manic or Mixed
- Interventions
- divalproex sodium
- Drug
- Lead sponsor
- Abbott
- Industry
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2004
- U.S. locations
- 1
- States / cities
- North Chicago, Illinois
- Conditions
- Bipolar Disorder
- Interventions
- Divalproex Sodium (Depakote ER)
- Drug
- Lead sponsor
- Abbott
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 370 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2003
- U.S. locations
- 18
- States / cities
- Cerritos, California • Torrance, California • Washington D.C., District of Columbia + 15 more
- Conditions
- Bipolar Disorder, Manic
- Interventions
- Lumateperone, Placebo
- Drug
- Lead sponsor
- Intra-Cellular Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 351 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 22
- States / cities
- Bentonville, Arkansas • Little Rock, Arkansas • Anaheim, California + 15 more
- Conditions
- Bipolar-I Disorder With Mania or Mania With Mixed Features
- Interventions
- KarXT, Placebo
- Drug · Other
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 23
- States / cities
- Bentonville, Arkansas • Little Rock, Arkansas • Anaheim, California + 19 more
- Conditions
- Bipolar Disorder
- Interventions
- Lamotrigine + Aripiprazole, Lamotrigine + Placebo
- Drug
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,169 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 62
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Anaheim, California + 55 more
- Conditions
- Bipolar Disorder, Weight Gain
- Interventions
- Topiramate, Placebo
- Drug
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 10 Years to 18 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Bipolar Disorder Type I With Mania or Mania With Mixed Features
- Interventions
- KarXT, Placebo
- Drug · Other
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 28
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • Culver City, California + 23 more
- Conditions
- Bipolar I Disorder
- Interventions
- Extended-Release Carbamazepine
- Drug
- Lead sponsor
- Validus Pharmaceuticals
- Industry
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 161 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 26
- States / cities
- Altamonte Springs, Florida • Fort Lauderdale, Florida • Gainesville, Florida + 22 more
- Conditions
- Mixed Mania Bipolar Disorder
- Interventions
- Lamotrigine, Sodium Valproate
- Drug
- Lead sponsor
- Beth Israel Medical Center
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2007
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Bipolar 1 Disorder
- Interventions
- RAP-219, Placebo
- Drug · Other
- Lead sponsor
- Rapport Therapeutics Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 253 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 20
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • Chino, California + 17 more
- Conditions
- Bipolar Disorder, Mania, Mixed Mania
- Interventions
- Allopurinol
- Drug
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Los Angeles, California